Using laboratory-based infection models to develop better antibiotic dosing regimens

A domestic PhD scholarship is available from the NHMRC-funded Centre of Research Excellence in Redefining Antimicrobial Use to Reduce Resistance - CRE REDUCE - for a motivated and independent healthcare practitioner or scientist to use state-of-the-art laboratory based infection models to develop a better understanding of dosing regimens that can maximise bacterial killing and suppress the emergence of antibiotic resistance. This PhD will seek to describe the antibiotic concentrations associated with maximal antibiotic effects and will provide the opportunity for the student to learn advanced pharmacokinetic and pharmacodynamic modelling skills as well as develop skills in project design and management. Ideally the applicant should hold an Honours or Master’s degree with adequate previous research experience. The projects would be conducted at Centre for Translational Anti-Infective Pharmacodynamics at the School of Pharmacy, The University of Queensland in Brisbane, Australia.