Critically ill adult patient sub-population PK study: Multi-centre study of patients receiving life-support (ASAP-ECMO)
Clinical problem: There is an absence of data describing the PK of antimicrobials in critically ill adult patients requiring a form of life support called extra-corporeal membrane oxygenation (ECMO).
Generating new knowledge: ASAP-ECMO is a PK Study of patients receiving ECMO (6 ICUs in Australia, New Zealand, South Korea, Switzerland) and will describe the PK of ceftriaxone, meropenem, ciprofloxacin, piperacillin-tazobactam, vancomycin, caspofungin, oseltamivir.
Capacity building: A/Prof Kiran Shekar (funded by Metro North Fellowship; Mid-Career Researcher MCR1), Ms Vesa Cheng (CRE REDUCE-CRE ACTIONS co-funding; PhD2)
Collaborations: Led by CIA Roberts (NHMRC Fellow; UQ and RBWH) and Prof John Fraser (The Prince Charles Hospital; TPCH)
Funding: Confirmed Intensive Care Foundation, Australia and New Zealand College of Anaesthetists (ANZCA), CRE ACTIONS (led by Prof John Fraser, CIA Roberts is also a CI).
