Dose optimisation of antibacterials in patients post-lung transplant
A domestic PhD scholarship is available from the NHMRC-funded Centre of Research Excellence in Redefining Antimicrobials Use to Reduce Resistance - CRE REDUCE - at The University of Queensland for a motivated and independent healthcare practitioner to improve pharmacotherapy for patients that have received a lung transplant. Due to the significance of the transplant procedure and the associated immunosuppression, use of maximally effective antibacterial therapy is very important to improve patient outcomes. This PhD will seek to innovate antibacterial dosing in these patients using pharmacokinetic studies and will provide the opportunity for the student to learn advanced pharmacokinetic modelling skills as well as develop skills in project design, project management and statistical analysis. Ideally the applicant should hold an Honours or Master’s degree with adequate previous research experience. The projects would be conducted at The Prince Charles Hospital in Brisbane, Australia.
Dose optimisation of antifungals and antivirals in post-lung transplant patients
A domestic PhD scholarship is available from the NHMRC-funded Centre of Research Excellence in Redefining Antimicrobial Use to Reduce Resistance - CRE REDUCE - at The University of Queensland for a motivated and independent healthcare practitioner to improve pharmacotherapy for patients that have received a lung transplant. Due to the significance of the transplant procedure and the associated immunosuppression, use of maximally effective antiviral and antifungal prophylaxis is very important to improve patient outcomes. This PhD will seek to innovate antiviral and antifungal dosing in these patients using pharmacokinetic studies and will provide the opportunity for the student to learn advanced pharmacokinetic modelling skills as well as develop skills in project design, management and statistical analysis. Ideally the applicant should hold an Honours or Masters degree with adequate previous research experience. The projects would be conducted at The Prince Charles Hospital in Brisbane, Australia.
Beta-lactam antibiotic dose optimization in critically ill patient
A domestic PhD scholarship is available from the NHMRC-funded Centre of Research Excellence in Redefining Antimicrobial Use to Reduce Resistance - CRE REDUCE - at The University of Queensland for a motivated and independent healthcare practitioner to investigate sophisticated approaches for optimising dosing for critically ill patients. Critically ill patients have high morbidity and mortality rates associated with severe infections and a contributing factor to this is considered to be suboptimal antibiotic dosing. Beta-lactam therapeutic drug monitoring supportive by Bayesian forecasting software is a dosing intervention highly likely to improve the accuracy of drug dosing in these patients, but is yet to be systematically evaluated. This PhD will seek to measure the effectiveness of these dose optimisation interventions and will provide the opportunity for the student to learn advanced pharmacokinetic modelling and dose optimisation skills as well as develop skills in project design, project management and statistical analysis. Ideally the applicant should hold an Honours or Master’s degree with adequate previous research experience. The projects would be conducted at The Royal Brisbane and Women’s Hospital in Brisbane, Australia.
Using laboratory-based infection models to develop better antibiotic dosing regimens
A domestic PhD scholarship is available from the NHMRC-funded Centre of Research Excellence in Redefining Antimicrobial Use to Reduce Resistance - CRE REDUCE - for a motivated and independent healthcare practitioner or scientist to use state-of-the-art laboratory based infection models to develop a better understanding of dosing regimens that can maximise bacterial killing and suppress the emergence of antibiotic resistance. This PhD will seek to describe the antibiotic concentrations associated with maximal antibiotic effects and will provide the opportunity for the student to learn advanced pharmacokinetic and pharmacodynamic modelling skills as well as develop skills in project design and management. Ideally the applicant should hold an Honours or Master’s degree with adequate previous research experience. The projects would be conducted at Centre for Translational Anti-Infective Pharmacodynamics at the School of Pharmacy, The University of Queensland in Brisbane, Australia.
