Analysis of data using population pharmacokinetic models
Pmetrics Pharmacometric Modelling Workshop Program
DAY 1 – Pharmacokinetic modelling | |
08:00-08:25 | Registrations |
08:25- 08:30 | Welcome Prof Jason Roberts |
08:30-09:15 | Introduction to Pharmacometrics Prof Michael Neely |
09:15-09.45 | Review of pre-workshop tutorial Dr Suzanne Parker |
109:45-10.45 | Understanding Pmetrics model and data files Dr Suzanne Parker |
10:45-11.15 | Morning tea |
11.15-12.45 | Fitting data to models in Pmetrics Dr Tavey Dorofaeff |
12.45-13.15 | Lunch |
13.15-15.00 | Details and plotting of Pmetrics objects Dr Fekade Sime |
15:00-15:30 | Afternoon tea |
15.30-17.30 | Pmetrics modelling exercises* |
DAY 2 – Pharmacokinetic simulations / Pharmacodynamic modelling | |
9:00 – 10:30 | Simulating and probability of target attainment with Pmetrics Dr Patty Mitre |
10:30-11:00 | Morning Tea |
11:00-12:30 | Simulation exercises* Tutors |
12:30-13:30 | Lunch |
13:30-14:00 | Pharmacodynamic principles Dr Aaron Heffernan |
14:00-15:30 | Building pharmacodynamic models Pharmacodynamic modelling exercises* Tutors |
15:30-16:00 | Afternoon Tea |
16:00-16.10 | Close Prof Jason Roberts |
| 16.10-17.00 | Self-directed modelling |
About Pmetrics pharmacometric modelling workshop
This Pmetrics pharmacometrics modelling workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians and researchers, intensive care physicians, transplant physicians and clinical pharmacologists. It is also suitable for basic researchers including pharmacologists and translational scientists wanting to learn robust methods for the analysis of data from pharmacokinetic studies.
Learning objectives
1. Using the Pmetrics package for R:
- Define pharmacokinetic (PK) and pharmacokinetic/pharmacodynamics(PK/PD) structural models that can be solved analytically and models that require differential equations
- Analyse PK and PK/PD datasets
- Perform basic Monte Carlo simulations for PK and PK/PD analysis
2. With the antimicrobial dosing software tool, users will explore:
- Application of pharmacometric methods to dose individualisation
- Optimise dosing for an individual patient