This Pmetrics pharmacometrics modelling workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians and researchers, intensive care physicians, transplant physicians and clinical pharmacologists. It is also suitable for basic researchers including pharmacologists and translational scientists wanting to learn robust methods for the analysis of data from pharmacokinetic studies.
Learning objectives
1. Using the Pmetrics package for R:
- Define pharmacokinetic (PK) and pharmacokinetic/pharmacodynamics(PK/PD) structural models that can be solved analytically and models that require differential equations
- Analyse PK and PK/PD datasets
- Perform basic Monte Carlo simulations for PK and PK/PD analysis
2. With the antimicrobial dosing software tool, users will explore:
- Application of pharmacometric methods to dose individualisation
- Optimise dosing for an individual patient
