Pmetrics Pharmacometric Modelling Workshop
Program
DAY 1 – Pharmacokinetic modelling^ | ||
08:00-08:25 | Registrations | |
08:25- 08:35 | Welcome | Prof Jason Roberts |
08:35-09:00 | Introduction to Pharmacometrics | Prof Michael Neely (1530 local time) |
09:00-09:30 | Review of pre-workshop tutorial | Dr Suzanne Parker |
09:30-10:00 | Understanding Pmetrics model and data files | Dr Suzanne Parker |
10:30-11:00 | Morning Tea | |
11.00-12:30 | Fitting data to models in Pmetrics | Prof Jason Roberts |
12:30-13:30 | Lunch | |
13:30-15:00 | Details and plotting of Pmetrics objects | Dr Fekade Sime |
15:00-15:30 | Afternoon Tea | |
15:30-17:30 | Pmetrics modelling exercises* | Tutors |
DAY 2 – Pharmacokinetic simulations / Pharmacodynamic modelling^ | ||
9:00 – 10:30 | Simulating and probability of target attainment with Pmetrics | Prof Cristina Sanches (2000 local time) |
10:30-11:00 | Morning Tea | |
11:00-12:30 | Simulation exercises* | Tutors |
12:30-13:30 | Lunch | |
13:30-14:30 | Pharmacodynamic principles | Dr Aaron Heffernan |
14:30-15:30 | Building pharmacodynamic models Pharmacodynamic modelling exercises | Tutors |
15:30-16:00 | Afternoon Tea | |
16:00-17:55 | Self-directed modelling | Tutors |
Closing | Prof Jason Roberts |
*Tutors
Platinum sponsors:
About Pmetrics pharmacometric modelling workshop
This Pmetrics pharmacometrics modelling workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians and researchers, intensive care physicians, transplant physicians and clinical pharmacologists. It is also suitable for basic researchers including pharmacologists and translational scientists wanting to learn robust methods for the analysis of data from pharmacokinetic studies.
Learning objectives
1. Using the Pmetrics package for R:
- Define pharmacokinetic (PK) and pharmacokinetic/pharmacodynamics(PK/PD) structural models that can be solved analytically and models that require differential equations
- Analyse PK and PK/PD datasets
- Perform basic Monte Carlo simulations for PK and PK/PD analysis
2. With the antimicrobial dosing software tool, users will explore:
- Application of pharmacometric methods to dose individualisation
- Optimise dosing for an individual patient
Venue
Building 71/918
Royal Brisbane & Women's Campus
HERSTON QLD 4029