BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients
Relevant Publications
Abdul-Aziz, M. H., Dulhunty, J. M., Rajbhandari, D., Roberts, J. A., & Lipman, J. (2024). Is it time to implement prolonged infusions of beta-lactam antibiotics in and beyond critical care settings?. Internal medicine journal, 54(12), 1931–1934. https://doi.org/10.1111/imj.16584
Abdul-Aziz, Mohd H., Hammond, Naomi E., Brett, Stephen J., Cotta, Menino O., De Waele, Jan J., Devaux, Anthony, Di Tanna, Gian Luca, Dulhunty, Joel M., Elkady, Hatem, Eriksson, Lars, Hasan, M Shahnaz, Khan, Ayesha Bibi, Lipman, Jeffrey, Liu, Xiaoqiu, Monti, Giacomo, Myburgh, John, Novy, Emmanuel, Omar, Shahed, Rajbhandari, Dorrilyn, Roger, Claire, Sjövall, Fredrik, Zaghi, Irene, Zangrillo, Alberto, Delaney, Anthony and Roberts, Jason A. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA. doi: 10.1001/jama.2024.9803
Dulhunty, Joel M., Brett, Stephen J., De Waele, Jan J., Rajbhandari, Dorrilyn, Laurent Billot, Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, Liu, Xiaoqiu, McGuinness, Shay, Mysore, Jayanthi, Paterson, David L., Peake, Sandra, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Myburgh, John A., Lipman, Jeffrey (2024) Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial. JAMA. Published online June 12, 2024. doi:10.1001/jama.2024.9779
Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman and Dulhunty, Joel M. (2023). Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]. Critical Care and Resuscitation, 25 (1), 60. doi: 10.1016/j.ccrj.2023.04.012
Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., Waele, Jan J. De, Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roger, Claire, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Dulhunty, Joel M. and For the BLING III Investigators (2021). Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis. Critical Care and Resuscitation, 23 (3), 273-284. doi: 10.51893/2021.3.oa4
Cotta, M. O., Dulhunty, J. M., Roberts, J. A., Myburgh, J., & Lipman, J. (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International journal of antimicrobial agents, 47(6), 436–438. doi.org/10.1016/j.ijantimicag.2016.02.017
Lipman, J., Brett, S. J., De Waele, J. J., Cotta, M. O., Davis, J. S., Finfer, S., Glass, P., Knowles, S., McGuinness, S., Myburgh, J., Paterson, D. L., Peake, S., Rajbhandari, D., Rhodes, A., Roberts, J. A., Shirwadkar, C., Starr, T., Taylor, C., Billot, L., & Dulhunty, J. M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 21(1), 63–68.
