Professor Jeffrey Lipman

Featured projects	Duration
Exploring the impact of altered and variable antimicrobial pharmacokinetics on bacterial killing and emergence of bacterial resistance. National Health and Medical Research Council
Develop informed consumer groups whose members participate as partners in CRE research projects and processes
Antibiotic penetration into epithelial lining fluid of mechanically ventilated patients with VAP and CAP.
Development of clinical practice guidelines on antimicrobial dosing incorporating new knowledge generated by the CRE REDUCE.
Exploring population variability of antimicrobial epithelial lining fluid penetration in patients with VAP.
PK studies of antimicrobials in patients with VAP, CAP/ PK of antimicrobials National Health and Medical Research Council
SaMpling Antibiotics in Renal Replacement Therapy (SMARRT). National Health and Medical Research Council
Therapeutic Drug Monitoring National Health and Medical Research Council
Antimicrobial pharmacokinetics in patients with cystic fibrosis, lung and bone marrow transplant. National Health and Medical Research Council
BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients National Health and Medical Research Council
Pharmacokinetics of Flucloxacillin and Lincomycin in burns patients. National Health and Medical Research Council
The PNEUDOS Study Program: defining novel and individualised antimicrobial dosing regimens for treatment of pneumonia in ICU National Health and Medical Research Council
Pharmacokinetics of antifungals in intensive care patients National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill paediatric patients National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill obese patients National Health and Medical Research Council
Therapeutic drug monitoring optimisation of antimicrobial exposures for critically ill, burns and transplant patients.
Continuous versus intermittent beta-lactams administration in critically ill patients with sepsis not receiving renal replacement therapy.

Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. Kucers the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 347-360) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Udy, Andrew and Lipman, Jeffrey (2012). Importance of high creatinine clearance for antibacterial treatment in sepsis. Sepsis management: PIRO and MODS. (pp. 171-197) edited by Jordi Rello, Jeffrey Lipman and Thiago Lisboa. Berlin, Germany: Springer. doi: 10.1007/978-3-642-03519-7_12

Carvajal, Carlos, Rello, Jordi and Lipman, Jeffrey (2011). Candida pneumonia in patients with hematological neoplasia. Pulmonary involvement in patients with hematological malignancies. (pp. 349-356) edited by Elie Azoulay. Berlin, Germany: Springer - Verlag. doi: 10.1007/978-3-642-15742-4_28

Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. Critical Care Update 2009. (pp. 128-142) edited by Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas. Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.

Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. Yearbook of Intensive Care and Emergency Medicine 2010. (pp. 495-506) edited by J.-L. Vincent. Brussels, Belgium: Springer Verlag. doi: 10.1007/978-3-642-10286-8

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. Patient safety and quality of care in intensive care medicine. (pp. 291-304) edited by Jean-Daniel Chiche and Leanne M. Aitken. Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.

Brown, Anthony F.T. and Lipman, Jeffrey (2008). Prehospital Care. Mechanical Ventilation: Clinical Applications and Pathophysiology. (pp. 307-319) Elsevier Inc.. doi: 10.1016/B978-0-7216-0186-1.50032-6

Cohen, Jeremy and Lipman, Jeffrey (2008). Use and abuse of antibiotics. Anaesthesia science. (pp. 128-136) edited by Nigel R. Webster and Helen F. Galley. Malden, MA, United States: Blackwell Publishing . doi: 10.1002/9780470755297.ch10

Brown, Anthony F. and Lipman, Jeffrey (2008). Pre-hospital Care. Mechanical ventilation: clinical applications and pathophysiology. (pp. 307-319) edited by P. J. Papadakos and B. Lachmann. Philadelphia, United States: Saunders.

Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. Sepsis: New strategies for management. (pp. 97-102) edited by Jordi Rello and Marcos I. Restrepo. London: Springer-Verlag. doi: 10.1007/978-3-540-79001-3

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-158) Berlin, Germany: Springer. doi: 10.1007/978-3-540-34406-3_13

Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. Infectious diseases in critical care. (pp. 122-146) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin, Germany; New York, U.S.A.: Springer. doi: 10.1007/978-3-540-34406-3_12

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-159) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin & Heidelberg, Germany; New York, USA: Springer - Verlag.

Cohen, Jeremy and Lipman, Jeffrey (2006). Use and Abuse of antibiotics. Anesthesia science. (pp. 128-139) edited by Nigel R. Webster and Helen F. Galley. Malden, Mass.: Blackwell Pub.

Lipman, J. and Saadia, R. (1999). Acute Respiratory Distress Syndrome. Cardiothoracic Trauma. (pp. 295-303) edited by Stephen Westaby and John A. Odell. New York US: Oxford Univ. Press.

Hopley, M. and Lipman, J. (1999). Tetanus - Pathophysiology. Oxford Textbook of Critical Care. (pp. 510-512) edited by Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M.. Oxford UK: Oxford University press.

Hon, H. and Lipman, J. (1999). Tetanus - Prevention and management. Oxford Textbook of Critical Care. (pp. 512-514) edited by Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M.. Oxford UK: Oxford Univ. Press.

Cotta, Menino O., Lipman, Jeffrey and De Waele, Jan (2023). Advancing precision-based antimicrobial dosing in critically ill patients. Intensive Care Medicine, 49 (3), 324-326. doi: 10.1007/s00134-022-06969-7

Ling, Lowell, Mui, Oliver Oi Yat, Laupland, Kevin B., Lefrant, Jean-Yves, Roberts, Jason A., Gopalan, Pragasan Dean, Lipman, Jeffrey, Joynt, Gavin M., Stelfox, Tom, Niven, Daniel, Paramalingam, Rameiya, Vonderhaar, Derek, Freebairn, Ross, Ling, Lowell, Leung, Patricia, Gopalan, Dean, Lefrant, Jean Yves, Lloret, Sophie, Elotmani, Loubna, Fourie, Cheryl, Saba, Renee, Carlisle, Dougal and Edwards, Felicity (2022). Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients. Journal of Intensive Care, 10 (1) 44. doi: 10.1186/s40560-022-00633-4

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

Menon, Rahul, Vasani, Sarju S, Widdicombe, Neil J and Lipman, Jeffrey (2022). Laryngeal injury following endotracheal intubation: Have you considered reflux?. Anaesthesia and Intensive Care, 51 (1), 0310057X2211024-19. doi: 10.1177/0310057x221102472

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9), 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Meropenem in Neurocritical Care Patients: a Prospective Two-Center Study. Antimicrobial Agents and Chemotherapy, 66 (8), e0014222. doi: 10.1128/aac.00142-22

Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168

Tsai, Danny, Chiong, Fabian, Secombe, Paul, Hnin, Khin Moe, Stewart, Penny, Goud, Rajendra, Woodman, Richard, Lipman, Jeffrey, Roberts, Jason and Hewagama, Saliya (2022). Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study. Internal Medicine Journal, 52 (6), 1048-1056. doi: 10.1111/imj.15171

Wiebe, Jordan, Lipman, Jeffrey and Reade, Michael C. (2022). A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit. Critical Care and Resuscitation, 24 (2), 183-187. doi: 10.51893/2022.2.OA8

Heffernan, Aaron J., Sime, Fekade B., Kumta, Nilesh, Wallis, Steven C., McWhinney, Brett, Ungerer, Jacobus, Wong, Gloria, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (6), e0218921. doi: 10.1128/aac.02189-21

Schlebusch, Sanmarié, Graham, Rikki M. A., Jennison, Amy V., Lassig-Smith, Melissa M., Harris, Patrick N. A., Lipman, Jeffrey, Ó Cuív, Páraic and Paterson, David L. (2022). Standard rectal swabs as a surrogate sample for gut microbiome monitoring in intensive care. BMC Microbiology, 22 (1) 99, 1-14. doi: 10.1186/s12866-022-02487-0

Arvaniti, Kostoula, Dimopoulos, George, Antonelli, Massimo, Blot, Koen, Creagh-Brown, Ben, Deschepper, Mieke, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Eckmann, Christian, Einav, Sharon, Francois, Guy, Fjeldsoee-Nielsen, Hans, Girardis, Massimo, Jovanovic, Bojan, Lindner, Matthias, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovestky, Fernando, Makikado, Luis Daniel Umezawa, Maseda, Emilio, Mikstacki, Adam, Montravers, Philippe, Paiva, José Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Tomescu, Dana ... Blot, Stijn (2022). Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: An international cohort study. International Journal of Antimicrobial Agents, 60 (1) 106591, 106591. doi: 10.1016/j.ijantimicag.2022.106591

Bitton, Eden, Zimmerman, Shmuel, Azevedo, Luciano Cesar Pontes, Benhamou, Dan, Cecconi, Maurizio, De Waele, Jan J., Lipman, Jeffrey, Martin-Loeches, Ignacio, Pirracchio, Romain, Scheeren, Thomas W.L., Leone, Marc and Einav, Sharon (2022). An international survey of adherence to Surviving Sepsis Campaign Guidelines 2016 regarding fluid resuscitation and vasopressors in the initial management of septic shock. Journal of Critical Care, 68, 144-154. doi: 10.1016/j.jcrc.2021.11.016

Ling, Lowell, Wong, Wai-Tat, Lipman, Jeffrey and Joynt, Gavin Matthew (2022). A narrative review on the approach to antimicrobial use in ventilated patients with multidrug resistant organisms in respiratory samples—to treat or not to treat? That is the question. Antibiotics, 11 (4) 452, 452. doi: 10.3390/antibiotics11040452

Sanches, Cristina, Alves, Geisa C. S., Farkas, Andras, da Silva, Samuel Dutra, de Castro, Whocely Victor, Chequer, Farah Maria Drummond, Beraldi-Magalhães, Francisco, Magalhães, Igor Rafael dos Santos, Baldoni, André de Oliveira, Chatfield, Mark D., Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2022). Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation. Antibiotics, 11 (4) 434, 434. doi: 10.3390/antibiotics11040434

Tabah, Alexis, Lipman, Jeffrey, Barbier, François, Buetti, Niccolò, Timsit, Jean-François and on behalf of the ESCMID Study Group for Infections in Critically Ill Patients—ESGCIP (2022). Use of antimicrobials for bloodstream infections in the intensive care unit, a clinically oriented review. Antibiotics, 11 (3) 362, 362. doi: 10.3390/antibiotics11030362

Farkas, Andras, Oikonomou, Katerina, Ghanbar, Mohammad, Villasurda, Phillip, Varghese, Julie, Lipman, Jeffrey, Sassine, Joseph, Ranganathan, Dwarakanathan and Roberts, Jason A. (2022). Population pharmacokinetics of intraperitoneal gentamicin and the impact of varying dwell times on pharmacodynamic target attainment in patients with acute peritonitis undergoing peritoneal dialysis. Antimicrobial Agents and Chemotherapy, 66 (2) e01679-21, e0167921. doi: 10.1128/aac.01679-21

Lee, Anna, De Waele, Jan J. and Lipman, Jeffrey (2022). Antibiotic dosing in sustained low-efficiency daily dialysis (SLEDD): Basic concepts and dosing strategies. Journal of Critical Care, 67, 104-107. doi: 10.1016/j.jcrc.2021.10.019

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513

Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21

Tait, Jessica R., Bilal, Hajira, Rogers, Kate E., Lang, Yinzhi, Kim, Tae-Hwan, Zhou, Jieqiang, Wallis, Steven C., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Paterson, David L., Lipman, Jeffrey, Bergen, Phillip J., Roberts, Jason A., Nation, Roger L. and Landersdorfer, Cornelia B. (2022). Effect of different Piperacillin-Tazobactam dosage regimens on synergy of the combination with Tobramycin against Pseudomonas aeruginosa for the pharmacokinetics of critically ill patients in a dynamic infection model. Antibiotics, 11 (1) 101, 101. doi: 10.3390/antibiotics11010101

Parker, Suzanne L., Wallis, Steven C., Fourie, Cheryl, Lassig-Smith, Melissa, Starr, Therese, Chikatamarla, Avinash, Dorofaeff, Tavey, Chatfield, Mark D., Lipman, Jeffrey and Roberts, Jason A. (2022). Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples. Analytical and Bioanalytical Chemistry, 414 (6), 2155-2162. doi: 10.1007/s00216-021-03851-1

Heffernan, A.J., Sime, F.B., Lim, S. Mohd Sazlly, Adiraju, S., Wallis, S.C., Lipman, J., Grant, G.D. and Roberts, J.A. (2022). Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?. International Journal of Antimicrobial Agents, 59 (3) 106537, 106537. doi: 10.1016/j.ijantimicag.2022.106537

Garbez, Nicolas, Mbatchi, Litaty C., Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Caspofungin population pharmacokinetic analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Clinical Pharmacokinetics, 61 (5), 673-686. doi: 10.1007/s40262-021-01062-6

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo and Roberts, Jason A. (2021). Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study. Antibiotics, 10 (12) 1559. doi: 10.3390/antibiotics10121559

Garbez, Nicolas, Mbatchi, Litaty C., Maseda, Emilio, Luque, Sonia, Grau, Santiago, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). A loading micafungin dose in critically ill patients undergoing continuous veno-venous hemofiltration or continuous veno-venous hemodiafiltration: a population pharmacokinetic analysis. Therapeutic Drug Monitoring, 43 (6), 747-755. doi: 10.1097/FTD.0000000000000874

Holley, Anthony, Droder, Brett, Reade, Michael, Lipman, Jeffrey, Pilcher, David, Litton, Edward, Karamujic, Nermin, Laupland, Kevin, Vallmuur, Kirsten, Delaney, Anthony and Cohen, Jeremy (2021). The need for an Australasian burns critical care standardised data collection tool. Critical Care and Resuscitation, 23 (4), 361-363. doi: 10.51893/2021.4.POV

Heffernan, Aaron J., Mohd Sazlly Lim, Sazlyna, Lipman, Jeffrey and Roberts, Jason A. (2021). A personalised approach to antibiotic pharmacokinetics and pharmacodynamics in critically ill patients. Anaesthesia Critical Care and Pain Medicine, 40 (6) 100970, 100970. doi: 10.1016/j.accpm.2021.100970

Niederman, Michael S., Baron, Rebecca M., Bouadma, Lila, Calandra, Thierry, Daneman, Nick, DeWaele, Jan, Kollef, Marin H., Lipman, Jeffrey and Nair, Girish B. (2021). Initial antimicrobial management of sepsis. Critical Care, 25 (1) 307, 307. doi: 10.1186/s13054-021-03736-w

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4

Garbez, Nicolas, Mbatchi, Litaty C., Louart, Guillaume, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?. Pharmaceutical Research, 38 (11), 1863-1871. doi: 10.1007/s11095-021-03137-2

Ramanan, Mahesh, Shorr, Andrew and Lipman, Jeffrey (2021). Ventriculitis: infection or inflammation. Antibiotics, 10 (10) 1246, 1246. doi: 10.3390/antibiotics10101246

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431

Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387

Tsai, Danny, Secombe, Paul, Chiong, Fabian, Ullah, Shahid, Lipman, Jeffrey and Hewagama, Saliya (2021). Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community‐acquired pneumonia – a retrospective study. Internal Medicine Journal, 53 (1), 51-60. doi: 10.1111/imj.15534

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Garbez, Nicolas, Mbatchi, Litaty, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Antimicrobial Agents and Chemotherapy, 65 (7) e02307-20, 1-13. doi: 10.1128/aac.02307-20

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7

Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4

Belveyre, Thibaut, Scala-Bertola, Julien, Esposito, Mathieu, Luc, Amandine, Lipman, Jeffrey and Novy, Emmanuel (2021). Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4), 479-485. doi: 10.1007/s13318-021-00688-y

Holley, Anthony D., Dulhunty, Joel, Udy, Andrew, Midwinter, Mark, Lukin, Bill, Stuart, Janine, Boots, Robert, Lassig-Smith, Melissa, Holley, Robert B., Paratz, Jenny and Lipman, Jeffrey (2021). Early sequential microcirculation assessment in shocked patients as a predictor of outcome: a prospective observational cohort study. Shock, 55 (5), 581-586. doi: 10.1097/SHK.0000000000001578

Smith, Samuel , Ketheesan, Sarangan , Touma, Emeile , Lipman, Jeffrey and Brown, Anthony F. T. (2021). Lorazepam challenge test for catatonia. Emergency Medicine Australasia, 33 (4) 1742-6723.13780, 763-764. doi: 10.1111/1742-6723.13780

Heffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5

Ling, Lowell, Joynt, Gavin Matthew and Lipman, Jeffrey (2021). A narrative review on antimicrobial therapy in septic shock: updates and controversies. Current Opinion in Anaesthesiology, 34 (2), 92-98. doi: 10.1097/ACO.0000000000000954

Agyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191

Holley, Anthony, Coatsworth, Nick and Lipman, Jeffrey (2021). The Australian response to the COVID-19 pandemic: A co-ordinated and effective strategy. Anaesthesia Critical Care and Pain Medicine, 40 (2) 100859. doi: 10.1016/j.accpm.2021.100859

Smith, Samuel L., Waters, Peadar S., Mirza, Wasif, Keogh, Cian, Lipman, Jeffrey, Cavallucci, David J., O'Rourke, Nicholas and Bryant, Richard D. (2021). Re-expansion pulmonary oedema with Takotsubo cardiomyopathy: a rare complication of giant hepatic cyst drainage. ANZ Journal of Surgery, 91 (11) ans.16745, 2524-2527. doi: 10.1111/ans.16745

Roberts, Leah W., Forde, Brian M., Hurst, Trish, Ling, Weiping, Nimmo, Graeme R., Bergh, Haakon, George, Narelle, Hajkowicz, Krispin, McNamara, John F., Lipman, Jeffrey, Permana, Budi, Schembri, Mark A., Paterson, David, Beatson, Scott A. and Harris, Patrick N. A. (2021). Genomic surveillance, characterization and intervention of a polymicrobial multidrug-resistant outbreak in critical care. Microbial Genomics, 7 (3) 000530. doi: 10.1099/mgen.0.000530

Heffernan, Aaron James, Sime, Fekade Bruck, Naicker, Saiyuri, Andrews, Katherine, Ellwood, David, Guerra-Valero, Yarmarly, Wallis, Steven, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason Alexander (2021). Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 100 (2) 115329, 115329. doi: 10.1016/j.diagmicrobio.2021.115329

Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8

Lonsdale, Dagan O. and Lipman, Jeffrey (2021). Global personalization of antibiotic therapy in critically ill patients. Expert Review of Precision Medicine and Drug Development, 6 (2), 87-93. doi: 10.1080/23808993.2021.1874823

Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20

Lonsdale, Dagan O., Shah, Reya V. and Lipman, Jeffrey (2020). Infection, sepsis and the inflammatory response: mechanisms and therapy. Frontiers in Medicine, 7 588863, 1-6. doi: 10.3389/fmed.2020.588863

Luyt, Charles-Edouard, Bouadma, Lila, Morris, Andrew Conway, Dhanani, Jayesh A., Kollef, Marin, Lipman, Jeffrey, Martin-Loeches, Ignacio, Nseir, Saad, Ranzani, Otavio T., Roquilly, Antoine, Schmidt, Matthieu, Torres, Antoni and Timsit, Jean-François (2020). Pulmonary infections complicating ARDS. Intensive Care Medicine, 46 (12), 2168-2183. doi: 10.1007/s00134-020-06292-z

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196

Perin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793

Heffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211

Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058

Martin-Loeches, Ignacio, Dickson, Robert, Torres, Antoni, Hanberger, Håkan, Lipman, Jeffrey, Antonelli, Massimo, de Pascale, Gennaro, Bozza, Fernando, Vincent, Jean Louis, Murthy, Srinivas, Bauer, Michael, Marshall, John, Cilloniz, Catia and Bos, Lieuwe D. (2020). The importance of airway and lung microbiome in the critically ill. Critical care, 24 (1) 537, 537. doi: 10.1186/s13054-020-03219-4

Rello, Jordi, Tejada, Sofia, Xu, Elena, Solé-Lleonart, Candela, Campogiani, Laura, Koulenti, Despoina, Ferreira-Coimbra, João and Lipman, Jeff (2020). Quality of evidence supporting surviving sepsis campaign recommendations. Anaesthesia Critical Care and Pain Medicine, 39 (4), 497-502. doi: 10.1016/j.accpm.2020.06.015

Nethathe, Gladness Dakalo, Cohen, Jeremy, Lipman, Jeffrey, Anderson, Ronald and Feldman, Charles (2020). Mineralocorticoid dysfunction during critical illness: a review of the evidence. Anesthesiology, 133 (2), 439-457. doi: 10.1097/ALN.0000000000003365

Hamilton, Rebekah, Kleinpell, Ruth, Lipman, Jeffrey and Davidson, Judy E. (2020). International facilitators and barriers to family engagement in the ICU: Results of a qualitative analysis. Journal of Critical Care, 58, 72-77. doi: 10.1016/j.jcrc.2020.04.011

Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7). doi: 10.1128/aac.02584-19

Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Jager, Nynke G. L., van Hest, Reinier M., Xie, Jiao, Wong, Gloria, Ulldemolins, Marta, Brüggemann, Roger J. M., Lipman, Jeffrey and Roberts, Jason A. (2020). Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations. Journal of Antimicrobial Chemotherapy, 75 (9), 2641-2649. doi: 10.1093/jac/dkaa187

Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Wicha, Sebastian G. (2020). An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy. Pharmaceutical Research, 37 (6) 96, 96. doi: 10.1007/s11095-020-02832-w

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413

Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey and Cohen, Jeremy (2020). There is no fire without smoke! Pathophysiology and treatment of inhalational injury in burns: a narrative review. Anaesthesia and Intensive Care, 48 (2), 0310057X2091328-122. doi: 10.1177/0310057x20913282

Ates, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A. and Dincer, Can (2020). On-site therapeutic drug monitoring. Trends in Biotechnology, 38 (11), 1262-1277. doi: 10.1016/j.tibtech.2020.03.001

Dhaese, Sofie A. M., Thooft, Alexander D. J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2020). Corrigendum to “Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study” [Journal of Critical Care 52 (2019) 75–79]. Journal of Critical Care, 56, 325-325. doi: 10.1016/j.jcrc.2019.09.020

Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766

Ling, Lowell, Joynt, Gavin M., Lipman, Jeff, Constantin, Jean-Michel and Joannes-Boyau, Olivier (2020). COVID-19: A critical care perspective informed by lessons learnt from other viral epidemics. Anaesthesia Critical Care & Pain Medicine, 39 (2), 163-166. doi: 10.1016/j.accpm.2020.02.002

Holley, Anthony, Cohen, Jeremy, Reade, Michael, Laupland, Kevin B. and Lipman, Jeffrey (2020). New guidelines for the management of severe thermal burns in the acute phase in adults and children: Is it time for a global surviving burn injury campaign (SBIC)?. Anaesthesia Critical Care and Pain Medicine, 39 (2), 195-196. doi: 10.1016/j.accpm.2020.03.009

Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason A., Kiel, Patrick J., Avedissian, Sean N., Rhodes, Nathaniel J. and Scheetz, Marc H. (2020). Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime. Clinical Pharmacokinetics, 59 (8), 1027-1036. doi: 10.1007/s40262-020-00873-3

Lonsdale, Dagan Osborne, Lipman, Jeffrey, Livermore, Amelia, McWhinney, Brett, Ungerer, Jacobus P.J. and Roberts, Jason A. (2020). Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function. Chemotherapy, 64 (4), 1-4. doi: 10.1159/000505057

Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Lipman, Jeffrey, Kumar, Anand, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason (2020). β-lactam antibiotic versus combined β-lactam antibiotic and single-daily dosing regimens of aminoglycosides for the treatment of serious infections: a meta-analysis. International Journal of Antimicrobial Agents, 55 (3) 105839, 105839. doi: 10.1016/j.ijantimicag.2019.10.020

Timsit, Jean-Francois, Lipman, Jeffrey and Bassetti, Matteo (2020). Antimicrobial de-escalation is part of appropriate antibiotic usage in ICU. Intensive Care Medicine, 46 (5), 1039-1042. doi: 10.1007/s00134-020-05951-5

Wong, Gloria, Taccone, Fabio, Villois, Paola, Scheetz, Marc H., Rhodes, Nathaniel J., Briscoe, Scott, McWhinney, Brett, Nunez-Nunez, Maria, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2020). β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill. Journal of Antimicrobial Chemotherapy, 75 (2), 429-433. doi: 10.1093/jac/dkz437

Koulenti, Despoina, Arvaniti, Kostoula, Judd, Mathew, Lalos, Natasha, Tjoeng, Iona, Xu, Elena, Armaganidis, Apostolos and Lipman, Jeffrey (2020). Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?. Antibiotics, 9 (2) 51, 51. doi: 10.3390/antibiotics9020051

Koulenti, Despoina, Xu, Elena, Song, Andrew, Mok, Isaac Yin Sum , Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Tsiodras, Sotirios and Lipman, Jeffrey (2020). Emerging treatment options for infections by multidrug-resistant gram-positive microorganisms. Microorganisms, 8 (2), 1-40. doi: 10.3390/microorganisms8020191

Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N.A. and Lipman, J. (2020). Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007). Clinical Microbiology and Infection, 26 (6), 801-801. doi: 10.1016/j.cmi.2020.01.016

Arulkumaran, Nishkantha, Routledge, Matthew, Schlebusch, Sanmarié, Lipman, Jeffrey and Conway Morris, Andrew (2020). Antimicrobial-associated harm in critical care: a narrative review. Intensive Care Medicine, 46 (2), 225-235. doi: 10.1007/s00134-020-05929-3

Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020). Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 (1) e01679-19. doi: 10.1128/aac.01679-19

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N. A. and Lipman, J. (2020). When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit. Clinical Microbiology and Infection, 26 (1), 35-40. doi: 10.1016/j.cmi.2019.07.007

Fujii, Motoki, Karumai, Toshiyuki, Yamamoto, Ryohei, Kobayashi, Eri, Ogawa, Kenta, Tounai, Mayuko, Lipman, Jeffrey and Hayashi, Yoshiro (2020). Pharmacokinetic and pharmacodynamic considerations in antimicrobial therapy for sepsis. Expert Opinion on Drug Metabolism and Toxicology, 16 (5), 1-16. doi: 10.1080/17425255.2020.1750597

Lonsdale, Dagan O. and Lipman, Jeffrey (2019). Antimicrobial resistance: we must pursue a collaborative, global approach and use a “one health” approach. Antibiotics, 8 (4) 237, 237. doi: 10.3390/antibiotics8040237

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658

Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey, Delaney, Anthony, Udy, Andrew, Lee, Richard, Litton, Edward, Cheung, Winston, Turner, Andrew, Garside, Tessa, Macken, Lewis, Reddi, Benjamin, Kol, Mark, Kazemi, Alex, Shah, Asim, Townsend, Shane and Cohen, Jeremy (2019). Survey of critical care practice in Australian and New Zealand burn referral centres. Critical Care and Resuscitation, 21 (4), 303-304.

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474

Ho, Kwok M., Rogers, Frederick B. and Lipman, Jeffrey (2019). The authors reply to: A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 (15), 1496-1497. doi: 10.1056/NEJMc1911302

Koulenti, Despoina, Xu, Elena, Yin Sum Mok, Isaac, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Lefamulin. Comment on: “Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms, 2019, 7, 270”. Microorganisms, 7 (10) 386, 386. doi: 10.3390/microorganisms7100386

Ballot, Daynia E., Bandini, Rosella, Nana, Trusha, Bosman, Noma, Thomas, Teena, Davies, Victor A., Cooper, Peter A., Mer, Mervyn and Lipman, Jeffrey (2019). A review of -multidrug-resistant Enterobacteriaceae in a neonatal unit in Johannesburg, South Africa. BMC Pediatrics, 19 (1) 320, 320. doi: 10.1186/s12887-019-1709-y

T.P. Wan, Winnie, Guerra Valero, Yarmarly, Choi, Gordon Y.S., Ordóñez Mejia, Jenny L., Wallis, Steven C., Joynt, Gavin M., Lipman, Jeffrey, Gomersall, Charles D. and Roberts, Jason A. (2019). In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration. International Journal of Antimicrobial Agents, 54 (2), 261-264. doi: 10.1016/j.ijantimicag.2019.03.018

Laupland, Kevin B., Tabah, Alexis, Kelway, Charlotte and Lipman, Jeffrey (2019). Does intermittent pneumatic compression PREVENT deep vein thrombosis in the ICU?. Anaesthesia Critical Care and Pain Medicine, 38 (4), 303-304. doi: 10.1016/j.accpm.2019.05.006

Ho, Kwok M., Holley, Anthony and Lipman, Jeffrey (2019). Vena Cava filters in severely-injured patients: one size does not fit all. Anaesthesia Critical Care and Pain Medicine, 38 (4), 305-307. doi: 10.1016/j.accpm.2019.07.003

Dhaese, Sofie A.M., Thooft, Alexander D.J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2019). Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study. Journal of Critical Care, 52, 75-79. doi: 10.1016/j.jcrc.2019.04.013

Koulenti, Despoina, Xu, Elena, Mok, Isaac Yin Sum, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Novel antibiotics for multidrug-resistant gram-positive microorganisms. Microorganisms, 7 (8), 270. doi: 10.3390/microorganisms7080270

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth, Corcoran, Tomas, Misur, Philip, Edibam, Cyrus, Baker, Ross I., Chamberlain, Jenny, Forsdyke, Claire and Rogers, Frederick B. (2019). A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 (4), 328-337. doi: 10.1056/NEJMoa1806515

Sumi, Chandra Datta, Heffernan, Aaron J., Lipman, Jeffery, Roberts, Jason A. and Sime, Fekade B. (2019). What antibiotic exposures are required to suppress the emergence of resistance for gram‑negative bacteria? A systematic review. Clinical Pharmacokinetics, 58 (11), 1407-1443. doi: 10.1007/s40262-019-00791-z

Economou, Caleb J. P., Xie, Jiao, Comadira, Gregory, Richards, Brent, Tallott, Mandy, Wallis, Steven C., Ordoñez, Jenny, Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International Journal of Antimicrobial Agents, 54 (3), 351-355. doi: 10.1016/j.ijantimicag.2019.06.027

Weber, Nicholas, Jackson, Kathryn, McWhinney, Brett, Ungerer, Jacobus, Kennedy, Glen, Lipman, Jeffrey and Roberts, Jason A. (2019). Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia. Journal of Infection and Chemotherapy, 25 (7), 503-508. doi: 10.1016/j.jiac.2019.02.014

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9

Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019). Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 (6) dkz069, 1662-1669. doi: 10.1093/jac/dkz069

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?. European Journal of Clinical Microbiology & Infectious Diseases, 38 (4), 637-647. doi: 10.1007/s10096-019-03486-2

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2). European Journal of Clinical Microbiology and Infectious Diseases, 38 (4), 649-649. doi: 10.1007/s10096-019-03518-x

De Backer, Daniel, Cecconi, Maurizio, Lipman, Jeffrey, Machado, Flavia, Myatra, Sheila Nainan, Ostermann, Marlies, Perner, Anders, Teboul, Jean-Louis, Vincent, Jean-Louis and Walley, Keith R. (2019). Challenges in the management of septic shock: a narrative review. Intensive Care Medicine, 45 (4), 420-433. doi: 10.1007/s00134-019-05544-x

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434

Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019). Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 (3), 211-224. doi: 10.1016/j.ijantimicag.2018.10.011

McCullough, James P.A., Lipman, Jeffrey and Presneill, Jeffrey J. (2018). The statistical curriculum within randomized controlled trials in critical illness. Critical Care Medicine, 46 (12), 1985-1990. doi: 10.1097/CCM.0000000000003380

Sakr, Yasser, Jaschinski, Ulrich, Wittebole, Xavier, Szakmany, Tamas, Lipman, Jeffrey, Namendys-Silva, Silvio A., Martin-Loeches, Ignacio, Leone, Marc, Lupu, Mary-Nicoleta and Vincent, Jean-Louis (2018). Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit. Open Forum Infectious Diseases, 5 (12), ofy313. doi: 10.1093/ofid/ofy313

Ballot, Daynia Elizabeth, Ramdin, Tanusha, White, Debbie Ann and Lipman, Jeffrey (2018). A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa. BMC Research Notes, 11 (1) 829, 829. doi: 10.1186/s13104-018-3946-9

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, 52 (4), 506-509. doi: 10.1016/j.ijantimicag.2018.07.008

Wong, Gloria, Briscoe, Scott, McWhinney, Brett, Ally, Mumtaz, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A (2018). Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. Journal of Antimicrobial Chemotherapy, 73 (11), 3087-3094. doi: 10.1093/jac/dky314

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018). The authors reply. Critical Care Medicine, 46 (7), e725-e726. doi: 10.1097/CCM.0000000000003164

Tsai, D., Stewart, P. C., Hewagama, S., Krishnaswamy, S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2018). Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis. Anaesthesia and Intensive Care, 46 (4), 374-380. doi: 10.1177/0310057X1804600405

Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018). New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 (7), 1-16. doi: 10.1080/17425255.2018.1484452

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016

Dhanani, J. A., Barnett, A. G., Lipman, J. and Reade, M. C. (2018). Strategies to reduce inappropriate laboratory blood test orders in intensive care are effective and safe: a before-and-after quality improvement study. Anaesthesia and Intensive Care, 46 (3), 313-320. doi: 10.1177/0310057X1804600309

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). Pharmacokinetics of intravenous posaconazole in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (6) e00242-18, e00242-18. doi: 10.1128/AAC.00242-18

Heffernan, A. J., Sime, F. B., Lipman, J. and Roberts, J. A. (2018). Individualising therapy to minimize bacterial multidrug resistance. Drugs, 78 (6), 621-641. doi: 10.1007/s40265-018-0891-9

Economou, Caleb J. P., Kielstein, Jan T., Czock, David, Xie, Jiao, Field, Jonathan, Richards, Brent, Tallot, Mandy, Visser, Adam, Koenig, Christina, Hafer, Carsten, Schmidt, Julius J., Lipman, Jeffrey and Roberts, Jason A. (2018). Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy. International Journal of Antimicrobial Agents, 52 (2), 151-157. doi: 10.1016/j.ijantimicag.2018.03.001

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057

Yadav, Rajbharan, Rogers, Kate E., Bergen, Phillip J., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling. Antimicrobial Agents and Chemotherapy, 62 (5) e00078, e00078-18. doi: 10.1128/AAC.00078-18

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269

Dahyot-Fizelier, Claire, Marchand, Sandrine and Lipman, Jeffrey (2018). Is augmented renal clearance the Holy Grail of antibiotic therapy failure in ventilator-acquired pneumonia?. Anaesthesia Critical Care & Pain Medicine, 37 (1), 5-6. doi: 10.1016/j.accpm.2017.12.003

Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018). Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 (2), 236-243. doi: 10.1097/CCM.0000000000002836

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023

Bergen, Phillip J., Bulitta, Jürgen B., Sime, Fekade B., Lipman, Jeffrey, McGregor, Megan J., Millen, Nada, Paterson, David L., Kirkpatrick, Carl M. J., Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 91 (1), 69-76. doi: 10.1016/j.diagmicrobio.2017.12.019

Tsai, D., Udy, A. A., Stewart, P. C., Gourley, S., Morick, N. M., Lipman, J. and Roberts, J. A. (2018). Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission. Anaesthesia and Intensive Care, 46 (1), 42-50. doi: 10.1177/0310057X1804600107

De Waele, Jan J., Akova, Murat, Antonelli, Massimo, Canton, Rafael, Carlet, Jean, De Backer, Daniel, Dimopoulos, George, Garnacho-Montero, José, Kesecioglu, Jozef, Lipman, Jeffrey, Mer, Mervyn, Paiva, José-Artur, Poljak, Mario, Roberts, Jason A., Rodriguez Bano, Jesus, Timsit, Jean-François, Zahar, Jean-Ralph and Bassetti, Matteo (2017). Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Medicine, 44 (2), 189-196. doi: 10.1007/s00134-017-5036-1

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030

Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2

de Prost, Nicholas, Lipman, Jeffrey and Mimoz, Olivier (2017). Therapeutic targets in necrotizing soft tissue infections. Intensive Care Medicine, 43 (11), 1717-1719. doi: 10.1007/s00134-017-4813-1

Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17

Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17

Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodriguez-Bano, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R. and Paterson, D.L. (2017). Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection, 23 (8), 533-541. doi: 10.1016/j.cmi.2016.10.023

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017). Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 (7) e016747, e016747. doi: 10.1136/bmjopen-2017-016747

Druery, Martha, Newcombe, Peter A., Cameron, Cate M. and Lipman, Jeffrey (2017). Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol. BMJ Open, 7 (6) e017545, e017545. doi: 10.1136/bmjopen-2017-017545

Badenes, Rafael, Oddo, Mauro, Suarez, Jose I., Antonelli, Massimo, Lipman, Jeffrey, Citerio, Giuseppe and Taccone, Fabio Silvio (2017). Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey. Critical Care, 21 (1) 159, 159. doi: 10.1186/s13054-017-1748-4

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019

Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16

Poulakou, Garyfallia, Matthaiou, Dimitrios K., Bassetti, Matteo, Erdem, Hakan, Dimopoulos, George, Curcio, Daniel J., Carlet, Jean, Lipman, Jeffrey, Timsit, Jean‑François, Giamarellou, Helen, Arfaras-Melainis, Angelos and Rello, Jordi (2017). “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Medicine, 43 (8), 1164-1166. doi: 10.1007/s00134-017-4796-y

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022

Pretorius, Carel J., Reade, Michael C., Warnholtz, Chris, McWhinney, Brett, Phua, Meng Mei, Lipman, Jeffrey and Ungerer, Jacobus P. J. (2017). Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients. Clinica Chimica Acta, 466, 72-77. doi: 10.1016/j.cca.2017.01.012

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2017). Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection. Chest, 151 (3), 586-596. doi: 10.1016/j.chest.2016.10.057

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014

Kollef, Marin H., Bassetti, Matteo, Francois, Bruno, Burnham, Jason, Dimopoulos, George, Garnacho-Montero, Jose, Lipman, Jeffrey, Luyt, Charles‑Edouard, Nicolau, David P., Postma, Maarten J., Torres, Antonio, Welte, Tobias and Wunderink, Richard G. (2017). The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship. Intensive Care Medicine, 43 (9), 1-11. doi: 10.1007/s00134-017-4682-7

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017). Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 (5), 221-226. doi: 10.1089/ars.2016.6845

Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017). Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 (2), 331-336. doi: 10.1097/CCM.0000000000002210

Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W. and Roberts, Jason A. (2017). Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 (1) e01763-16, e01763-16. doi: 10.1128/AAC.01763-16

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328

Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016). Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 56 (9), 1-12. doi: 10.1007/s40262-016-0495-z

Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 (2), 231-239. doi: 10.1097/QCO.0000000000000348

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 (12), 7402-7406. doi: 10.1128/AAC.01657-16

Playford, E. Geoffrey, Lipman, Jeffrey, Jones, Michael, Lau, Anna F., Kabir, Masrura, Chen, Sharon C. -A., Marriott, Deborah J., Seppelt, Ian, Gottlieb, Thomas, Cheung, Winston, Iredell, Jonathan R., McBryde, Emma S. and Sorrell, Tania C. (2016). Problematic dichotomization of risk for Intensive Care Unit (ICU)-acquired invasive candidiasis: results using a risk-predictive model to categorize 3 levels of risk from a multicenter prospective cohort of Australian ICU patients. Clinical Infectious Diseases, 63 (11), 1463-1469. doi: 10.1093/cid/ciw610

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (6), 748-752. doi: 10.1016/j.ijantimicag.2016.09.021

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (5), 542-546. doi: 10.1016/j.ijantimicag.2016.08.015

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16

Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016). Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 (5), 311-312. doi: 10.1016/j.accpm.2016.08.002

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35, 231-239. doi: 10.1016/j.jcrc.2016.06.022

Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016). Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 (10) dkw247, 2902-2908. doi: 10.1093/jac/dkw247

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016). Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 (10), e923-e929. doi: 10.1097/CCM.0000000000001823

Perner, Anders, Gordon, Anthony C., de Backer, Daniel, Dimopoulos, George, Russell, James A., Lipman, Jeffrey, Jensen, Jens‑Ulrik, Myburgh, John, Singer, Mervyn, Bellomo, Rinaldo and Walsh, Timothy (2016). Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy. Intensive Care Medicine, 42 (12), 1-12. doi: 10.1007/s00134-016-4577-z

Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Eley, Victoria, Callaway, Leonie, van Zundert, Andre, Lipman, Jeffrey and Gallois, Cindy (2016). Interpretation of care guidelines for obese women in labor: intergroup language and social identity. Journal of Language and Social Psychology, 36 (4), 388-414. doi: 10.1177/0261927X16668564

Labeau, Sonia O., Rello, Jordi, Dimopoulos, George, Lipman, Jeffrey, Sarikaya, Aklime, Ozturk, Candan, Vandijck, Dominique M., Vogelaers, Dirk, Vandewoude, Koenraad and Blot, Stijn I. (2016). The value of e-learning for the prevention of healthcare-associated infections. Infection Control and Hospital Epidemiology, 37 (9), 1052-1059. doi: 10.1017/ice.2016.107

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093

Eley, V. A., Callaway, L.K., Van Zundert, A. A. J., Lipman, J. and Gallois, C. (2016). Anaesthetists' experiences with the early labour epidural recommendation for obese parturients: a qualitative study. Anaesthesia and Intensive Care, 44 (5), 620-626. doi: 10.1177/0310057X1604400521

Eley, V. A., Van Zundert, A. A. J., Lipman, J. and Callaway, L. K. (2016). Anaesthetic management of obese parturients: what is the evidence supporting practice guidelines?. Anaesthesia and Intensive Care, 44 (5), 552-559. doi: 10.1177/0310057X1604400517

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016). Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 (9), 2509-2520. doi: 10.1093/jac/dkw153

Denny, Kerina Jane and Lipman, Jeffrey (2016). Bugs, genes, and the intensive care unit. Journal of Thoracic Disease, 8 (8), E788-E790. doi: 10.21037/jtd.2016.06.19

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4577-4584. doi: 10.1128/AAC.00531-16

Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 (240) 240, 240. doi: 10.1186/s13054-016-1426-y

Cristallini, Stefano, Hites, Maya, Kabtouri, Hakim, Roberts, Jason A., Beumier, Marjorie, Cotton, Frederic, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis, Creteur, Jacques and Taccone, Fabio Silvio (2016). New regimen for continuous infusion of vancomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4750-4756. doi: 10.1128/AAC.00330-16

Roger, Claire, Wallis, Steven C., Muller, Laurent, Saissi, Gilbert, Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2016). Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy. Antimicrobial Agents and Chemotherapy, 60 (8), 4901-4909. doi: 10.1128/AAC.00828-16

Ranganathan, Dwarakanathan, Naicker, Saiyuri, Wallis, Steven C., Lipman, Jeffrey, Ratanjee, Sharad K. and Roberts, Jason A. (2016). Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study). Peritoneal Dialysis International, 36 (4), 421-426. doi: 10.3747/pdi.2015.00062

Roberts, Darren M., Ranganathan, Dwarakanathan, Wallis, Steven C., Varghese, Julie M., Kark, Adrian, Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 36 (4), 415-420. doi: 10.3747/pdi.2015.00008

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 (6), 872-879. doi: 10.1002/bmc.3622

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016). Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 (6), 1643-1650. doi: 10.1093/jac/dkw043

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238

Barbier, Francois, Lipman, Jeffrey and Bonten, Marc J. M. (2016). In 2035, will all bacteria be multidrug-resistant? No. Intensive Care Medicine, 42 (12), 1-4. doi: 10.1007/s00134-016-4348-x

Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016). Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 (7), 961-979. doi: 10.1586/17512433.2016.1172209

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016). Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 (4), 259-268. doi: 10.1016/j.ijantimicag.2016.01.009

Tong, Steven Y. C., Nelson, Jane, Paterson, David L., Fowler, Vance G., Jr., Howden, Benjamin P., Cheng, Allen C., Chatfield, Mark, Lipman, Jeffrey, Van Hal, Sebastian, O'Sullivan, Matthew, Robinson, James O., Yahav, Dafna, Lye, David and Davis, Joshua S. (2016). CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial. Trials, 17 (1) 170, 170. doi: 10.1186/s13063-016-1295-3

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

Williams, Julian M., Greenslade, Jaimi H., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2016). Severity scores in emergency department patients with presumed infection: a prospective validation study. Critical Care Medicine, 44 (3), 539-547. doi: 10.1097/CCM.0000000000001427

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6

Dodds, Michelle M., Frazer, Callum D., Lipman, Jeffrey and Reade, Michael (2016). Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine. Critical Care and Resuscitation, 18 (1), 59-61.

Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016). Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 (2) dkv349, 464-470. doi: 10.1093/jac/dkv349

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15

Woodruff, Trent M., Wu, Mike C.-L., Morgan, Michael, Bain, Nathan T., Jeanes, Angela, Lipman, Jeffrey, Ting, Michael J., Boyd, Andrew W., Taylor, Stephen M. and Coulthard, Mark G. (2016). EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability. Shock, 45 (2), 184-191. doi: 10.1097/SHK.0000000000000494

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Williams, Julian M., Greenslade, Jaimi H., Dymond, Chelsea A., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffery (2016). Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study. European Journal of Emergency Medicine, 25 (2), 1-104. doi: 10.1097/MEJ.0000000000000419

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016). Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 (1), 206-214. doi: 10.1128/AAC.01543-15

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015). The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 (12) e0144740, e0144740. doi: 10.1371/journal.pone.0144740

McHugh, Leo, Seldon, Therese A., Brandon, Roslyn A., Kirk, James T., Rapisarda, Antony, Sutherland, Allison J., Presneill. Jeffrey J., Venter, Deon J., Lipman, Jeffrey, Thomas, Mervyn R., Klein Klouwenberg, Peter M.C., van Vught, Lonneke, Scicluna, Brendon, Bonten, Marc, Cremer, Olaf L., Schultz, Marcus J., van der Poll, Tom, Yager, Thomas D. and Brandon, Richard B. (2015). A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts. PLoS Medicine, 12 (12) e1001916, e1001916. doi: 10.1371/journal.pmed.1001916

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate ... Paul, Sanjoy (2015). A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 (11), 1298-1305. doi: 10.1164/rccm.201505-0857OC

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015). Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 (12), 3178-3183. doi: 10.1093/jac/dkv201

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 (5), 412-420. doi: 10.1097/MCC.0000000000000229

Wong, Wai-Tat, Choi, Gordon, Gomersall, Charles D. and Lipman, Jeffrey (2015). To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt. Current Opinion in Pharmacology, 24, 68-78. doi: 10.1016/j.coph.2015.07.003

Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015). Understanding PK/PD. Intensive Care Medicine, 42 (11), 1797-1800. doi: 10.1007/s00134-015-4032-6

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143

Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 (3), 249-253. doi: 10.1016/j.ijantimicag.2015.04.013

Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015). Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 (5), 594-599. doi: 10.1177/0310057X1504300507

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422

Carlier, Mieke, R

Professor Jeffrey Lipman

Researcher biography

Publications

Book Chapters

Journal Articles