Professor Jeffrey Lipman

Featured projects	Duration
Development of clinical practice guidelines on antimicrobial dosing incorporating new knowledge generated by the CRE REDUCE.
PK studies of antimicrobials in patients with VAP, CAP/ PK of antimicrobials National Health and Medical Research Council
Therapeutic Drug Monitoring National Health and Medical Research Council
BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients National Health and Medical Research Council
Exploring the impact of altered and variable antimicrobial pharmacokinetics on bacterial killing and emergence of bacterial resistance. National Health and Medical Research Council
The PNEUDOS Study Program: defining novel and individualised antimicrobial dosing regimens for treatment of pneumonia in ICU National Health and Medical Research Council
Antibiotic penetration into epithelial lining fluid of mechanically ventilated patients with VAP and CAP.
Exploring population variability of antimicrobial epithelial lining fluid penetration in patients with VAP.
SaMpling Antibiotics in Renal Replacement Therapy (SMARRT). National Health and Medical Research Council
Antimicrobial pharmacokinetics in patients with cystic fibrosis, lung and bone marrow transplant. National Health and Medical Research Council
Pharmacokinetics of Flucloxacillin and Lincomycin in burns patients. National Health and Medical Research Council
Pharmacokinetics of antifungals in intensive care patients National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill paediatric patients National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill obese patients National Health and Medical Research Council
Therapeutic drug monitoring optimisation of antimicrobial exposures for critically ill, burns and transplant patients.
Continuous versus intermittent beta-lactams administration in critically ill patients with sepsis not receiving renal replacement therapy.
Develop informed consumer groups whose members participate as partners in CRE research projects and processes

Niederman, Michael S., Koulenti, Despoina and Lipman, Jeffrey (2023). Antimicrobial agents with primary activity against gram-negative bacteria. Textbook of critical care. (pp. 853.e10-871.e10) edited by Jean-Louis Vincent, Frederick A. Moore, Rinaldo Bellomo and John J. Marini. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-75929-8.00116-7

Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. Kucers the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 347-360) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Lipman, Jeffrey (2013). Tetanus. Oh's Intensive Care Manual, Seventh Edition. (pp. 607-610) Elsevier. doi: 10.1016/B978-0-7020-4762-6.00055-2

Lipman, Jeffrey (2013). Principles of antibiotic use. Oh's Intensive Care Manual, Seventh Edition. (pp. 738-742) Elsevier. doi: 10.1016/B978-0-7020-4762-6.00072-2

Udy, Andrew and Lipman, Jeffrey (2012). Importance of high creatinine clearance for antibacterial treatment in sepsis. Sepsis management: PIRO and MODS. (pp. 171-197) edited by Jordi Rello, Jeffrey Lipman and Thiago Lisboa. Berlin, Germany: Springer. doi: 10.1007/978-3-642-03519-7_12

Carvajal, Carlos, Rello, Jordi and Lipman, Jeffrey (2011). Candida pneumonia in patients with hematological neoplasia. Pulmonary involvement in patients with hematological malignancies. (pp. 349-356) edited by Elie Azoulay. Berlin, Germany: Springer - Verlag. doi: 10.1007/978-3-642-15742-4_28

Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. Yearbook of Intensive Care and Emergency Medicine 2010. (pp. 495-506) edited by J.-L. Vincent. Brussels, Belgium: Springer Verlag. doi: 10.1007/978-3-642-10286-8

Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. Critical Care Update 2009. (pp. 128-142) edited by Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas. Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. Patient safety and quality of care in intensive care medicine. (pp. 291-304) edited by Jean-Daniel Chiche and Leanne M. Aitken. Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.

Brown, Anthony F.T. and Lipman, Jeffrey (2008). Prehospital Care. Mechanical Ventilation: Clinical Applications and Pathophysiology. (pp. 307-319) Elsevier Inc.. doi: 10.1016/B978-0-7216-0186-1.50032-6

Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. Sepsis: New strategies for management. (pp. 97-102) edited by Jordi Rello and Marcos I. Restrepo. London: Springer-Verlag. doi: 10.1007/978-3-540-79001-3

Brown, Anthony F. and Lipman, Jeffrey (2008). Pre-hospital Care. Mechanical ventilation: clinical applications and pathophysiology. (pp. 307-319) edited by P. J. Papadakos and B. Lachmann. Philadelphia, United States: Saunders.

Cohen, Jeremy and Lipman, Jeffrey (2008). Use and abuse of antibiotics. Anaesthesia science. (pp. 128-136) edited by Nigel R. Webster and Helen F. Galley. Malden, MA, United States: Blackwell Publishing . doi: 10.1002/9780470755297.ch10

Holley, Anthony and Lipman, Jeffrey (2008). Principles of Pharmacology in the Critically Ill. Critical Care Nephrology, Second Edition. (pp. 31-36) Elsevier. doi: 10.1016/B978-1-4160-4252-5.50008-3

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-159) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin & Heidelberg, Germany; New York, USA: Springer - Verlag.

Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. Infectious diseases in critical care. (pp. 122-146) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin, Germany; New York, U.S.A.: Springer. doi: 10.1007/978-3-540-34406-3_12

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. Infectious diseases in critical care. (pp. 147-158) Berlin, Germany: Springer. doi: 10.1007/978-3-540-34406-3_13

Cohen, Jeremy and Lipman, Jeffrey (2006). Use and Abuse of antibiotics. Anesthesia science. (pp. 128-139) edited by Nigel R. Webster and Helen F. Galley. Malden, Mass.: Blackwell Pub.

Lipman, J. and Saadia, R. (1999). Acute Respiratory Distress Syndrome. Cardiothoracic Trauma. (pp. 295-303) edited by Stephen Westaby and John A. Odell. New York US: Oxford Univ. Press.

Hopley, M. and Lipman, J. (1999). Tetanus - Pathophysiology. Oxford Textbook of Critical Care. (pp. 510-512) edited by Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M.. Oxford UK: Oxford University press.

Hon, H. and Lipman, J. (1999). Tetanus - Prevention and management. Oxford Textbook of Critical Care. (pp. 512-514) edited by Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M.. Oxford UK: Oxford Univ. Press.

Coisy, Fabien, Ajavon, Florian, Lipman, Jeffrey, Lefrant, Jean-Yves and Bobbia, Xavier (2025). Transfusion strategy in the most critically patients with trauma brain injury: Differences to other populations?. Anaesthesia Critical Care and Pain Medicine, 44 (2) 101490, 101490. doi: 10.1016/j.accpm.2025.101490

Khan, Ayesha Bibi, Abdul-Aziz, Mohd Hafiz, Hindle, Lucy, Lipman, Jeffrey, Simelela, Fetolang and Omar, Shahed (2025). Continuous versus intermittent bolus dosing of beta-lactam antibiotics in a South African multi-disciplinary intensive care unit: a randomized controlled trial. Journal of Infection, 90 (5) 106487, 1-6. doi: 10.1016/j.jinf.2025.106487

Eley, Victoria A., Navarro, Severine, Martin, Elizabeth, Amoako, Akwasi, Hartel, Gunter, Woods, Christine, Lu, Yan, Lipman, Jeffrey, Roberts, Jason, Tang, Mimi and Callaway, Leonie (2025). Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial. BMC Pregnancy and Childbirth, 25 (1) 353. doi: 10.1186/s12884-025-07484-5

Roberts, J. A., Heffernan, A. J., Chai, M. G., Harris, P. N. A., Legg, A., Farkas, A., Laupland, K., Dhanani, J., Fourie, C., Murray, L., Abdul-Aziz, H., Ungerer, J., McWhinney, B., Lipman, J. and Cotta, M. O. (2025). Resistance Optimised Antibiotic Dosing (The ROAD Study): Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? A pilot study. CMI Communications, 2 (1) 105051, 105051. doi: 10.1016/j.cmicom.2024.105051

Koulenti, Despoina, Roger, Claire and Lipman, Jeffrey (2025). Antibiotic dosing optimization in critically ill patients. Intensive Care Medicine, 51 (3), 603-606. doi: 10.1007/s00134-025-07822-3

Kumta, Nilesh, Heffernan, Aaron J., Liu, Xin, Parker, Suzanne L., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wai, Wong Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2025). Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. International Journal of Antimicrobial Agents, 65 (5) 107461, 107461-5. doi: 10.1016/j.ijantimicag.2025.107461

Kong, Daming, Roberts, Jason A., Lipman, Jeffrey, Taccone, Fabio Silvio, Cohen-Wolkowiez, Michael, Sime, Fekade B., Tsai, Danny, De Cock, Pieter A. J. G., Jaruratanasirikul, Sutep, Dhaese, Sofie A. M., Udy, Andrew A., Felton, Timothy W., Michelet, Robin, Thibault, Celine, Koomen, Jeroen V., Eleveld, Douglas J., Struys, Michel M. R. F., De Waele, Jan J., Colin, Pieter J., Damen, Caroline and PIP/TAZ Consortium (2024). A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderly. Clinical Pharmacokinetics, 64 (1) 769329, 107-126. doi: 10.1007/s40262-024-01460-6

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Liu, Xin, Parker, Suzanne, Wallis, Steven, Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2024). Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patients. Antimicrobial Agents and Chemotherapy, 69 (2), e0060124. doi: 10.1128/aac.00601-24

Dulhunty, Joel M., Roberts, Jason A. and Lipman, Jeffrey (2024). Continuous vs intermittent β-lactam antibiotic infusions for sepsis-Reply. JAMA: The Journal of the American Medical Association, 333 (2), 174-175. doi: 10.1001/jama.2024.23275

Druery, Martha, Das, Arpita, Warren, Jacelle, Newcombe, Peter A, Lipman, Jeffrey and Cameron, Cate M (2024). The ‘AfterBurn’ Longitudinal Exploratory (ABLE) study: Cohort profile. Injury, 55 (12) 111908, 111908. doi: 10.1016/j.injury.2024.111908

Abdul-Aziz, Mohd H., Dulhunty, Joel M., Rajbhandari, Dorrilyn, Roberts, Jason A. and Lipman, Jeffrey (2024). Is it time to implement prolonged infusions of beta-lactam antibiotics in and beyond critical care settings?. Internal Medicine Journal, 54 (12), 1931-1934. doi: 10.1111/imj.16584

Dorofaeff, Tavey, Valero, Yarmarly Guerra, Coulthard, Mark G., Wallis, Steven C., Chatfield, Mark D., Lister, Paula, Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2024). Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?. Bioanalysis, 16 (16), 873-881. doi: 10.1080/17576180.2024.2377912

Taraporewalla, K., Barach, P., Lipman, J. and Van Zundert, A. (2024). The Effectiveness of the Constraint-Led Approach in Developing Medical Procedural Skills. Universal Library of Medical and Health Sciences, 2 (2), 11-18. doi: 10.70315/uloap.ulmhs.2024.0202003

Druery, Martha, Das, Arpita, Warren, Jacelle, Newcombe, Peter A., Lipman, Jeffrey and Cameron, Cate M. (2024). Early predictors of health-related quality of life outcomes at 12 months post-burn: ABLE study. Injury, 55 (6) 111545, 1-9. doi: 10.1016/j.injury.2024.111545

Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study. ASAIO Journal, 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120

Taraporewalla, K., Barach, P., Lipman, J. and Van Zundert, A. (2024). The Efficiency of the Constraint-Led Approach in Teaching External Chest Compressions to Medical Students. Universal Library of Medical and Health Sciences, 2 (1), 70-77. doi: 10.70315/uloap.ulmhs.2024.0201009

Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3

Helset, Elin, Cheng, Vesa, Sporsem, Hilde, Thorstensen, Christian, Nordoy, Ingvild, Gammelsrud, Karianne Wiger, Hanssen, Gorm, Ponzi, Erica, Lipman, Jeffrey and von Der Lippe, Elisabeth (2024). Meropenem pharmacokinetic/pharmacodynamic target attainment and clinical response in ICU patients: A prospective observational study. Acta Anaesthesiologica Scandinavica, 68 (4), 502-511. doi: 10.1111/aas.14376

Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology Spectrum, 12 (2) e0306523, 1-16. doi: 10.1128/spectrum.03065-23

Dejonckheere, Marie, Antonelli, Massimo, Arvaniti, Kostoula, Blot, Koen, CreaghBrown, Ben, de Lange, Dylan W., De Waele, Jan, Deschepper, Mieke, Dikmen, Yalim, Dimopoulos, George, Eckmann, Christian, Francois, Guy, Girardis, Massimo, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovestky, Fernando, Maseda, Emilio, Montravers, Philippe, Mikstacki, Adam, Paiva, JoseArtur, Pereyra, Cecilia, Rello, Jordi, Timsit, JeanFrancois, Vogelaers, Dirk and Blot, Stijn (2024). Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection. Journal of Intensive Medicine, 4 (1), 81-93. doi: 10.1016/j.jointm.2023.06.004

Nethathe, Gladness D., Lipman, Jeffrey, Anderson, Ronald, Fuller, Peter J. and Feldman, Charles (2024). Glucocorticoids with or without fludrocortisone in septic shock: a narrative review from a biochemical and molecular perspective. British Journal of Anaesthesia, 132 (1), 53-65. doi: 10.1016/j.bja.2023.10.034

Margalit, Ili, Yahav, Dafna, Hoffman, Tomer, Tabah, Alexis, Ruckly, Stéphane, Barbier, François, Singer, Pierre, Timsit, Jean-François, Prendki, Virginie, Buetti, Niccolò, Hamid, Hytham K. S., Saidahmed, Elfayadh, Karar, Ali Adil Ali, Mc Cree, Melanie, Mer, Mervyn, Adeola, Fowotade, Idowu, Olusola, Oladimeji, Motunrayo, Asiyanbi, Gabriel, Desalu, Ibironke, Olatosi, John, Ugwu, Euphemia Mgbosoro, Yakubu, Saidu Yusuf, Misra, Krushna Chandra, Sheshala, Kaladhar, Mukherjee, Sudipta, Ghosh, Pralay, Chandran, Jagadish, Dsilva, Carol ... Lipman, Jeffrey (2024). Correction: Presentation, management, and outcomes of older compared to younger adults with hospital-acquired bloodstream infections in the intensive care unit: a multicenter cohort study (Infection, (2024), 10.1007/s15010-024-02304-y). Infection, 52 (6), 2565-2566. doi: 10.1007/s15010-024-02377-9

Taraporewalla, Kersi, Eriksson, Lars, Barach, Paul, Lipman, Jeffrey and Zundert, André (2024). Approaches to teaching medical procedural skills: a scoping review. Medical Research Archives, 12 (5), 1-20. doi: 10.18103/mra.v12i4.5394

Maasdorp, S. D., Paruk, F., De Vasconcellos, K., Grion, C., Joubert, I., Joynt, G., Kalafatis, N., Lapinsky, S. E., Lipman, J., Malbrain, M. L. N. G., Mrara, B., Richards, G. A., Spruyt, M., Van der Merwe, E., Vincent, J.-L. and Van der Merwe, L. J. (2023). Core competencies in critical care for general medical practitioners in South Africa: a Delphi study. Southern African Journal of Critical Care, 67-74. doi: 10.7196/sajcc.2023.v39i3.1261

Lala, Raushan C. B., Homes, Ryan A. P., Lipman, Jeffrey and Midwinter, Mark J. (2023). Interobserver reliability for manual analysis of sidestream darkfield videomicroscopy clips after resizing in ImageJ. Intensive Care Medicine Experimental, 11 (1) 88, 88. doi: 10.1186/s40635-023-00572-w

Chai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras and Cotta, Menino O. (2023). Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101296, 101296. doi: 10.1016/j.accpm.2023.101296

Maasdorp, S. D., Paruk, F., de Vasconcellos, K., Grion, C., Joubert,, Joynt, G. M., Kalafatis, N., Lapinsky, S. E., Lipman, J., Malbrain, M. L. N. G., Mrara, B., Richards, G. A., Spruyt, M. G. L., Merwe, E. van der, Vincent, J. L. and Merwe, L. J. van der (2023). Core competencies in critical care for general medical practitioners in South Africa: A Delphi study. Southern African Journal of Critical Care, 39 (3), 67-74. doi: 10.7196/SAJCC.2023.v39i3.1261

Ho, Kwok M., Lee, Anna, Wu, William, Chan, Matthew T. V., Ling, Lowell, Lipman, Jeffrey, Roberts, Jason, Litton, Edward, Joynt, Gavin M. and Wong, Martin (2023). Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the question. Journal of Geriatric Cardiology, 20 (11), 813-823. doi: 10.26599/1671-5411.2023.11.004

Boulet, Nicolas, Boussere, Amal, Mezzarobba, Myriam, Sofonea, Mircea T., Payen, Didier, Lipman, Jeffrey, Laupland, Kevin B., Rello, Jordi, Lefrant, Jean-Yves, Muller, Laurent, Roger, Claire, Pirracchio, Romain, Mura, Thibault and Boudemaghe, Thierry (2023). Activité des réanimations françaises à partir d’une base de données nationale entre 2013 et 2019 : une gravité en augmentation, mais des durées de séjour et un taux de mortalité en baisse. Anesthésie & Réanimation, 9 (5-6), 485-497. doi: 10.1016/j.anrea.2023.10.003

Boulet, Nicolas, Boussere, Amal, Mezzarobba, Myriam, Sofonea, Mircea T., Payen, Didier, Lipman, Jeffrey, Laupland, Kevin B., Rello, Jordi, Lefrant, Jean-Yves, Muller, Laurent, Roger, Claire, Pirracchio, Romain, Mura, Thibault and Boudemaghe, Thierry (2023). Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate. Anaesthesia Critical Care and Pain Medicine, 42 (5) 101228, 1-8. doi: 10.1016/j.accpm.2023.101228

Alli, Ahmad, Paruk, Fathima, Roger, Claire, Lipman, Jeffrey, Calleemalay, Daren, Wallis, Steven C., Scribante, Juan, Richards, Guy A. and Roberts, Jason A. (2023). Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery. PLoS One, 18 (9) e0291425, 1-14. doi: 10.1371/journal.pone.0291425

Denny, Kerina J., Lea, Rodney A., Lindell-Innes, Ross, Haupt, Larisa M., Heffernan, Aaron J., Harvey, Nicholas R., Hughes, Oliver, Cao, Van T., Stuart, Janine, Paterson, David L., McNamara, John F., Ungerer, Jacobus P.J., Pretorius, Carel J., Griffiths, Lyn R. and Lipman, Jeffrey (2023). Diagnosing sepsis in the ICU: comparison of a gene expression signature to pre-existing biomarkers. Journal of Critical Care, 76 154286, 1-6. doi: 10.1016/j.jcrc.2023.154286

Jeffrey, Mark, Denny, Kerina J., Lipman, Jeffrey and Conway Morris, Andrew (2023). Differentiating infection, colonisation, and sterile inflammation in critical illness: the emerging role of host-response profiling. Intensive Care Medicine, 49 (7), 760-771. doi: 10.1007/s00134-023-07108-6

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Garcia, Leandro Sousa, Souza Carvalho, Brenda Karoline, Costa, Amanda Araujo, Fachi, Mariana Millan, de Liz, Marcus Vinicius, de Souza, Alexandra Brito, Safe, Izabella Picinin, Pontarolo, Roberto, Wallis, Steven, Lipman, Jeffrey, Roberts, Jason A. and Cordeiro-Santos, Marcelo (2023). Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis. Tropical Medicine and Infectious Disease, 8 (6) 312, 1-10. doi: 10.3390/tropicalmed8060312

Shah, Reya V., Kipper, Karin, Baker, Emma H., Barker, Charlotte I. S., Oldfield, Isobel, Philips, Barbara J., Johnston, Atholl, Lipman, Jeffrey, Rhodes, Andrew, Basarab, Marina, Sharland, Mike, Almahdi, Sarraa, Wake, Rachel M., Standing, Joseph F. and Lonsdale, Dagan O. (2023). Population pharmacokinetic study of Benzylpenicillin in critically unwell adults. Antibiotics, 12 (4) 643, 643. doi: 10.3390/antibiotics12040643

Joynt, Gavin Matthew, Ling, Lowell, Wong, Wai Tat and Lipman, Jeffrey (2023). Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes. Expert Review of Clinical Pharmacology, 16 (8), 703-714. doi: 10.1080/17512433.2023.2194629

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Roberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002

Cotta, Menino O., Lipman, Jeffrey and De Waele, Jan (2023). Advancing precision-based antimicrobial dosing in critically ill patients. Intensive Care Medicine, 49 (3), 324-326. doi: 10.1007/s00134-022-06969-7

Ling, Lowell, Mui, Oliver Oi Yat, Laupland, Kevin B., Lefrant, Jean-Yves, Roberts, Jason A., Gopalan, Pragasan Dean, Lipman, Jeffrey, Joynt, Gavin M., Stelfox, Tom, Niven, Daniel, Paramalingam, Rameiya, Vonderhaar, Derek, Freebairn, Ross, Ling, Lowell, Leung, Patricia, Gopalan, Dean, Lefrant, Jean Yves, Lloret, Sophie, Elotmani, Loubna, Fourie, Cheryl, Saba, Renee, Carlisle, Dougal and Edwards, Felicity (2022). Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients. Journal of Intensive Care, 10 (1) 44, 1-10. doi: 10.1186/s40560-022-00633-4

Alonso, Julio M., Lipman, Jeffrey and Shekar, Kiran (2022). A novel barrier device and method for protection against airborne pathogens during endotracheal intubation. European Journal of Anaesthesiology, 39 (11), 900-903. doi: 10.1097/EJA.0000000000001731

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

Menon, Rahul, Vasani, Sarju S, Widdicombe, Neil J. and Lipman, Jeffrey (2022). Laryngeal injury following endotracheal intubation: have you considered reflux?. Anaesthesia and Intensive Care, 51 (1), 14-19. doi: 10.1177/0310057x221102472

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9) 1211, 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study. Antimicrobial Agents and Chemotherapy, 66 (8) e0014222, 1-12. doi: 10.1128/aac.00142-22

Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168

Tsai, Danny, Chiong, Fabian, Secombe, Paul, Hnin, Khin Moe, Stewart, Penny, Goud, Rajendra, Woodman, Richard, Lipman, Jeffrey, Roberts, Jason and Hewagama, Saliya (2022). Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study. Internal Medicine Journal, 52 (6), 1048-1056. doi: 10.1111/imj.15171

Wiebe, Jordan, Lipman, Jeffrey and Reade, Michael C. (2022). A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit. Critical Care and Resuscitation, 24 (2), 183-187. doi: 10.51893/2022.2.OA8

Heffernan, Aaron J., Sime, Fekade B., Kumta, Nilesh, Wallis, Steven C., McWhinney, Brett, Ungerer, Jacobus, Wong, Gloria, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (6), e0218921. doi: 10.1128/aac.02189-21

Schlebusch, Sanmarié, Graham, Rikki M. A., Jennison, Amy V., Lassig-Smith, Melissa M., Harris, Patrick N. A., Lipman, Jeffrey, Ó Cuív, Páraic and Paterson, David L. (2022). Standard rectal swabs as a surrogate sample for gut microbiome monitoring in intensive care. BMC Microbiology, 22 (1) 99, 1-14. doi: 10.1186/s12866-022-02487-0

Nethathe, Gladness Dakalo, Lipman, Jeffrey, Anderson, Ronald and Feldman, Charles (2022). CIRMI-a new term for a concept worthy of further exploration: a narrative review. Annals of Translational Medicine, 10 (11). doi: 10.21037/atm-21-5572

Arvaniti, Kostoula, Dimopoulos, George, Antonelli, Massimo, Blot, Koen, Creagh-Brown, Ben, Deschepper, Mieke, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Eckmann, Christian, Einav, Sharon, Francois, Guy, Fjeldsoee-Nielsen, Hans, Girardis, Massimo, Jovanovic, Bojan, Lindner, Matthias, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovestky, Fernando, Makikado, Luis Daniel Umezawa, Maseda, Emilio, Mikstacki, Adam, Montravers, Philippe, Paiva, José Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Tomescu, Dana ... Blot, Stijn (2022). Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: An international cohort study. International Journal of Antimicrobial Agents, 60 (1) 106591, 106591. doi: 10.1016/j.ijantimicag.2022.106591

Bitton, Eden, Zimmerman, Shmuel, Azevedo, Luciano Cesar Pontes, Benhamou, Dan, Cecconi, Maurizio, De Waele, Jan J., Lipman, Jeffrey, Martin-Loeches, Ignacio, Pirracchio, Romain, Scheeren, Thomas W.L., Leone, Marc and Einav, Sharon (2022). An international survey of adherence to Surviving Sepsis Campaign Guidelines 2016 regarding fluid resuscitation and vasopressors in the initial management of septic shock. Journal of Critical Care, 68, 144-154. doi: 10.1016/j.jcrc.2021.11.016

Ling, Lowell, Wong, Wai-Tat, Lipman, Jeffrey and Joynt, Gavin Matthew (2022). A narrative review on the approach to antimicrobial use in ventilated patients with multidrug resistant organisms in respiratory samples—to treat or not to treat? That is the question. Antibiotics, 11 (4) 452, 452. doi: 10.3390/antibiotics11040452

Sanches, Cristina, Alves, Geisa C. S., Farkas, Andras, da Silva, Samuel Dutra, de Castro, Whocely Victor, Chequer, Farah Maria Drummond, Beraldi-Magalhães, Francisco, Magalhães, Igor Rafael dos Santos, Baldoni, André de Oliveira, Chatfield, Mark D., Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2022). Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation. Antibiotics, 11 (4) 434, 434. doi: 10.3390/antibiotics11040434

Tabah, Alexis, Lipman, Jeffrey, Barbier, François, Buetti, Niccolò, Timsit, Jean-François and on behalf of the ESCMID Study Group for Infections in Critically Ill Patients—ESGCIP (2022). Use of antimicrobials for bloodstream infections in the intensive care unit, a clinically oriented review. Antibiotics, 11 (3) 362, 362. doi: 10.3390/antibiotics11030362

Lee, Anna, De Waele, Jan J. and Lipman, Jeffrey (2022). Antibiotic dosing in sustained low-efficiency daily dialysis (SLEDD): Basic concepts and dosing strategies. Journal of Critical Care, 67, 104-107. doi: 10.1016/j.jcrc.2021.10.019

Farkas, Andras, Oikonomou, Katerina, Ghanbar, Mohammad, Villasurda, Phillip, Varghese, Julie, Lipman, Jeffrey, Sassine, Joseph, Ranganathan, Dwarakanathan and Roberts, Jason A. (2022). Population pharmacokinetics of intraperitoneal gentamicin and the impact of varying dwell times on pharmacodynamic target attainment in patients with acute peritonitis undergoing peritoneal dialysis. Antimicrobial Agents and Chemotherapy, 66 (2) e01679-21, e0167921. doi: 10.1128/aac.01679-21

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513

Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21

Tait, Jessica R., Bilal, Hajira, Rogers, Kate E., Lang, Yinzhi, Kim, Tae-Hwan, Zhou, Jieqiang, Wallis, Steven C., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Paterson, David L., Lipman, Jeffrey, Bergen, Phillip J., Roberts, Jason A., Nation, Roger L. and Landersdorfer, Cornelia B. (2022). Effect of different Piperacillin-Tazobactam dosage regimens on synergy of the combination with Tobramycin against Pseudomonas aeruginosa for the pharmacokinetics of critically ill patients in a dynamic infection model. Antibiotics, 11 (1) 101, 101. doi: 10.3390/antibiotics11010101

Parker, Suzanne L., Wallis, Steven C., Fourie, Cheryl, Lassig-Smith, Melissa, Starr, Therese, Chikatamarla, Avinash, Dorofaeff, Tavey, Chatfield, Mark D., Lipman, Jeffrey and Roberts, Jason A. (2022). Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples. Analytical and Bioanalytical Chemistry, 414 (6), 2155-2162. doi: 10.1007/s00216-021-03851-1

Heffernan, A.J., Sime, F.B., Lim, S. Mohd Sazlly, Adiraju, S., Wallis, S.C., Lipman, J., Grant, G.D. and Roberts, J.A. (2022). Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?. International Journal of Antimicrobial Agents, 59 (3) 106537, 106537. doi: 10.1016/j.ijantimicag.2022.106537

Garbez, Nicolas, Mbatchi, Litaty C., Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Caspofungin population pharmacokinetic analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Clinical Pharmacokinetics, 61 (5), 673-686. doi: 10.1007/s40262-021-01062-6

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo and Roberts, Jason A. (2021). Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study. Antibiotics, 10 (12) 1559, 1559. doi: 10.3390/antibiotics10121559

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4

Garbez, Nicolas, Mbatchi, Litaty C., Maseda, Emilio, Luque, Sonia, Grau, Santiago, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). A loading micafungin dose in critically ill patients undergoing continuous veno-venous hemofiltration or continuous veno-venous hemodiafiltration: a population pharmacokinetic analysis. Therapeutic Drug Monitoring, 43 (6), 747-755. doi: 10.1097/FTD.0000000000000874

Heffernan, Aaron J., Mohd Sazlly Lim, Sazlyna, Lipman, Jeffrey and Roberts, Jason A. (2021). A personalised approach to antibiotic pharmacokinetics and pharmacodynamics in critically ill patients. Anaesthesia Critical Care and Pain Medicine, 40 (6) 100970, 100970. doi: 10.1016/j.accpm.2021.100970

Niederman, Michael S., Baron, Rebecca M., Bouadma, Lila, Calandra, Thierry, Daneman, Nick, DeWaele, Jan, Kollef, Marin H., Lipman, Jeffrey and Nair, Girish B. (2021). Initial antimicrobial management of sepsis. Critical Care, 25 (1) 307, 307. doi: 10.1186/s13054-021-03736-w

Holley, Anthony, Droder, Brett, Reade, Michael, Lipman, Jeffrey, Pilcher, David, Litton, Edward, Karamujic, Nermin, Laupland, Kevin, Vallmuur, Kirsten, Delaney, Anthony and Cohen, Jeremy (2021). The need for an Australasian burns critical care standardised data collection tool. Critical Care and Resuscitation, 23 (4), 361-363. doi: 10.51893/2021.4.POV

Garbez, Nicolas, Mbatchi, Litaty C., Louart, Guillaume, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?. Pharmaceutical Research, 38 (11), 1863-1871. doi: 10.1007/s11095-021-03137-2

Ramanan, Mahesh, Shorr, Andrew and Lipman, Jeffrey (2021). Ventriculitis: infection or inflammation. Antibiotics, 10 (10) 1246, 1246. doi: 10.3390/antibiotics10101246

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431

Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387

Tsai, Danny, Secombe, Paul, Chiong, Fabian, Ullah, Shahid, Lipman, Jeffrey and Hewagama, Saliya (2021). Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community‐acquired pneumonia – a retrospective study. Internal Medicine Journal, 53 (1), 51-60. doi: 10.1111/imj.15534

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Garbez, Nicolas, Mbatchi, Litaty, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Antimicrobial Agents and Chemotherapy, 65 (7) e02307-20, 1-13. doi: 10.1128/aac.02307-20

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7

Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4

Torisson, Gustav, Bruun Madsen, Martin, Schmidt Davidsen, Agnes, Perner, Anders, Lipman, Jeffrey, Dulhunty, Joel and Sjövall, Fredrik (2021). A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock. Critical Care Explorations, 3 (5) e0383, 1-10. doi: 10.1097/CCE.0000000000000383

Belveyre, Thibaut, Scala-Bertola, Julien, Esposito, Mathieu, Luc, Amandine, Lipman, Jeffrey and Novy, Emmanuel (2021). Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4), 479-485. doi: 10.1007/s13318-021-00688-y

Holley, Anthony D., Dulhunty, Joel, Udy, Andrew, Midwinter, Mark, Lukin, Bill, Stuart, Janine, Boots, Robert, Lassig-Smith, Melissa, Holley, Robert B., Paratz, Jenny and Lipman, Jeffrey (2021). Early sequential microcirculation assessment in shocked patients as a predictor of outcome: a prospective observational cohort study. Shock, 55 (5), 581-586. doi: 10.1097/SHK.0000000000001578

Smith, Samuel , Ketheesan, Sarangan , Touma, Emeile , Lipman, Jeffrey and Brown, Anthony F. T. (2021). Lorazepam challenge test for catatonia. Emergency Medicine Australasia, 33 (4) 1742-6723.13780, 763-764. doi: 10.1111/1742-6723.13780

Heffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5

Ling, Lowell, Joynt, Gavin Matthew and Lipman, Jeffrey (2021). A narrative review on antimicrobial therapy in septic shock: updates and controversies. Current Opinion in Anaesthesiology, 34 (2), 92-98. doi: 10.1097/ACO.0000000000000954

Agyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191

Holley, Anthony, Coatsworth, Nick and Lipman, Jeffrey (2021). The Australian response to the COVID-19 pandemic: A co-ordinated and effective strategy. Anaesthesia Critical Care and Pain Medicine, 40 (2) 100859. doi: 10.1016/j.accpm.2021.100859

Smith, Samuel L., Waters, Peadar S., Mirza, Wasif, Keogh, Cian, Lipman, Jeffrey, Cavallucci, David J., O'Rourke, Nicholas and Bryant, Richard D. (2021). Re-expansion pulmonary oedema with Takotsubo cardiomyopathy: a rare complication of giant hepatic cyst drainage. ANZ Journal of Surgery, 91 (11) ans.16745, 2524-2527. doi: 10.1111/ans.16745

Roberts, Leah W., Forde, Brian M., Hurst, Trish, Ling, Weiping, Nimmo, Graeme R., Bergh, Haakon, George, Narelle, Hajkowicz, Krispin, McNamara, John F., Lipman, Jeffrey, Permana, Budi, Schembri, Mark A., Paterson, David, Beatson, Scott A. and Harris, Patrick N. A. (2021). Genomic surveillance, characterization and intervention of a polymicrobial multidrug-resistant outbreak in critical care. Microbial Genomics, 7 (3) 000530. doi: 10.1099/mgen.0.000530

Heffernan, Aaron James, Sime, Fekade Bruck, Naicker, Saiyuri, Andrews, Katherine, Ellwood, David, Guerra-Valero, Yarmarly, Wallis, Steven, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason Alexander (2021). Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 100 (2) 115329, 115329. doi: 10.1016/j.diagmicrobio.2021.115329

Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8

Lonsdale, Dagan O. and Lipman, Jeffrey (2021). Global personalization of antibiotic therapy in critically ill patients. Expert Review of Precision Medicine and Drug Development, 6 (2), 87-93. doi: 10.1080/23808993.2021.1874823

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20

Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20

Lonsdale, Dagan O., Shah, Reya V. and Lipman, Jeffrey (2020). Infection, sepsis and the inflammatory response: mechanisms and therapy. Frontiers in Medicine, 7 588863, 1-6. doi: 10.3389/fmed.2020.588863

Luyt, Charles-Edouard, Bouadma, Lila, Morris, Andrew Conway, Dhanani, Jayesh A., Kollef, Marin, Lipman, Jeffrey, Martin-Loeches, Ignacio, Nseir, Saad, Ranzani, Otavio T., Roquilly, Antoine, Schmidt, Matthieu, Torres, Antoni and Timsit, Jean-François (2020). Pulmonary infections complicating ARDS. Intensive Care Medicine, 46 (12), 2168-2183. doi: 10.1007/s00134-020-06292-z

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196

Perin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793

Heffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z

Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211

Martin-Loeches, Ignacio, Dickson, Robert, Torres, Antoni, Hanberger, Håkan, Lipman, Jeffrey, Antonelli, Massimo, de Pascale, Gennaro, Bozza, Fernando, Vincent, Jean Louis, Murthy, Srinivas, Bauer, Michael, Marshall, John, Cilloniz, Catia and Bos, Lieuwe D. (2020). The importance of airway and lung microbiome in the critically ill. Critical care, 24 (1) 537, 537. doi: 10.1186/s13054-020-03219-4

Rello, Jordi, Tejada, Sofia, Xu, Elena, Solé-Lleonart, Candela, Campogiani, Laura, Koulenti, Despoina, Ferreira-Coimbra, João and Lipman, Jeff (2020). Quality of evidence supporting surviving sepsis campaign recommendations. Anaesthesia Critical Care and Pain Medicine, 39 (4), 497-502. doi: 10.1016/j.accpm.2020.06.015

Nethathe, Gladness Dakalo, Cohen, Jeremy, Lipman, Jeffrey, Anderson, Ronald and Feldman, Charles (2020). Mineralocorticoid dysfunction during critical illness: a review of the evidence. Anesthesiology, 133 (2), 439-457. doi: 10.1097/ALN.0000000000003365

Hamilton, Rebekah, Kleinpell, Ruth, Lipman, Jeffrey and Davidson, Judy E. (2020). International facilitators and barriers to family engagement in the ICU: Results of a qualitative analysis. Journal of Critical Care, 58, 72-77. doi: 10.1016/j.jcrc.2020.04.011

Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7) e02584-19. doi: 10.1128/aac.02584-19

Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Jager, Nynke G. L., van Hest, Reinier M., Xie, Jiao, Wong, Gloria, Ulldemolins, Marta, Brüggemann, Roger J. M., Lipman, Jeffrey and Roberts, Jason A. (2020). Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations. Journal of Antimicrobial Chemotherapy, 75 (9), 2641-2649. doi: 10.1093/jac/dkaa187

Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Wicha, Sebastian G. (2020). An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy. Pharmaceutical Research, 37 (6) 96, 96. doi: 10.1007/s11095-020-02832-w

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413

Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey and Cohen, Jeremy (2020). There is no fire without smoke! Pathophysiology and treatment of inhalational injury in burns: a narrative review. Anaesthesia and Intensive Care, 48 (2), 0310057X2091328-122. doi: 10.1177/0310057x20913282

Ates, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A. and Dincer, Can (2020). On-site therapeutic drug monitoring. Trends in Biotechnology, 38 (11), 1262-1277. doi: 10.1016/j.tibtech.2020.03.001

Dhaese, Sofie A. M., Thooft, Alexander D. J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2020). Corrigendum to “Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study” [Journal of Critical Care 52 (2019) 75–79]. Journal of Critical Care, 56, 325-325. doi: 10.1016/j.jcrc.2019.09.020

Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766

Ling, Lowell, Joynt, Gavin M., Lipman, Jeff, Constantin, Jean-Michel and Joannes-Boyau, Olivier (2020). COVID-19: A critical care perspective informed by lessons learnt from other viral epidemics. Anaesthesia Critical Care & Pain Medicine, 39 (2), 163-166. doi: 10.1016/j.accpm.2020.02.002

Holley, Anthony, Cohen, Jeremy, Reade, Michael, Laupland, Kevin B. and Lipman, Jeffrey (2020). New guidelines for the management of severe thermal burns in the acute phase in adults and children: Is it time for a global surviving burn injury campaign (SBIC)?. Anaesthesia Critical Care and Pain Medicine, 39 (2), 195-196. doi: 10.1016/j.accpm.2020.03.009

Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason A., Kiel, Patrick J., Avedissian, Sean N., Rhodes, Nathaniel J. and Scheetz, Marc H. (2020). Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime. Clinical Pharmacokinetics, 59 (8), 1027-1036. doi: 10.1007/s40262-020-00873-3

Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Lipman, Jeffrey, Kumar, Anand, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason (2020). β-lactam antibiotic versus combined β-lactam antibiotic and single-daily dosing regimens of aminoglycosides for the treatment of serious infections: a meta-analysis. International Journal of Antimicrobial Agents, 55 (3) 105839, 105839. doi: 10.1016/j.ijantimicag.2019.10.020

Lonsdale, Dagan Osborne, Lipman, Jeffrey, Livermore, Amelia, McWhinney, Brett, Ungerer, Jacobus P.J. and Roberts, Jason A. (2020). Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function. Chemotherapy, 64 (4), 1-4. doi: 10.1159/000505057

Timsit, Jean-Francois, Lipman, Jeffrey and Bassetti, Matteo (2020). Antimicrobial de-escalation is part of appropriate antibiotic usage in ICU. Intensive Care Medicine, 46 (5), 1039-1042. doi: 10.1007/s00134-020-05951-5

Wong, Gloria, Taccone, Fabio, Villois, Paola, Scheetz, Marc H., Rhodes, Nathaniel J., Briscoe, Scott, McWhinney, Brett, Nunez-Nunez, Maria, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2020). β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill. Journal of Antimicrobial Chemotherapy, 75 (2), 429-433. doi: 10.1093/jac/dkz437

Koulenti, Despoina, Arvaniti, Kostoula, Judd, Mathew, Lalos, Natasha, Tjoeng, Iona, Xu, Elena, Armaganidis, Apostolos and Lipman, Jeffrey (2020). Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?. Antibiotics, 9 (2) 51, 51. doi: 10.3390/antibiotics9020051

Koulenti, Despoina, Xu, Elena, Song, Andrew, Mok, Isaac Yin Sum , Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Tsiodras, Sotirios and Lipman, Jeffrey (2020). Emerging treatment options for infections by multidrug-resistant gram-positive microorganisms. Microorganisms, 8 (2) 191, 1-40. doi: 10.3390/microorganisms8020191

Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N.A. and Lipman, J. (2020). Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007). Clinical Microbiology and Infection, 26 (6), 801-801. doi: 10.1016/j.cmi.2020.01.016

Arulkumaran, Nishkantha, Routledge, Matthew, Schlebusch, Sanmarié, Lipman, Jeffrey and Conway Morris, Andrew (2020). Antimicrobial-associated harm in critical care: a narrative review. Intensive Care Medicine, 46 (2), 225-235. doi: 10.1007/s00134-020-05929-3

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020). Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 (1) e01679-19. doi: 10.1128/aac.01679-19

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N. A. and Lipman, J. (2020). When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit. Clinical Microbiology and Infection, 26 (1), 35-40. doi: 10.1016/j.cmi.2019.07.007

Fujii, Motoki, Karumai, Toshiyuki, Yamamoto, Ryohei, Kobayashi, Eri, Ogawa, Kenta, Tounai, Mayuko, Lipman, Jeffrey and Hayashi, Yoshiro (2020). Pharmacokinetic and pharmacodynamic considerations in antimicrobial therapy for sepsis. Expert Opinion on Drug Metabolism and Toxicology, 16 (5), 1-16. doi: 10.1080/17425255.2020.1750597

Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024

Lonsdale, Dagan O. and Lipman, Jeffrey (2019). Antimicrobial resistance: we must pursue a collaborative, global approach and use a “one health” approach. Antibiotics, 8 (4) 237, 237. doi: 10.3390/antibiotics8040237

Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey, Delaney, Anthony, Udy, Andrew, Lee, Richard, Litton, Edward, Cheung, Winston, Turner, Andrew, Garside, Tessa, Macken, Lewis, Reddi, Benjamin, Kol, Mark, Kazemi, Alex, Shah, Asim, Townsend, Shane and Cohen, Jeremy (2019). Survey of critical care practice in Australian and New Zealand burn referral centres. Critical Care and Resuscitation, 21 (4), 303-304.

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474

Ho, Kwok M., Rogers, Frederick B. and Lipman, Jeffrey (2019). The authors reply to: A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 (15), 1496-1497. doi: 10.1056/NEJMc1911302

Koulenti, Despoina, Xu, Elena, Yin Sum Mok, Isaac, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Lefamulin. Comment on: “Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms, 2019, 7, 270”. Microorganisms, 7 (10) 386, 386. doi: 10.3390/microorganisms7100386

Ballot, Daynia E., Bandini, Rosella, Nana, Trusha, Bosman, Noma, Thomas, Teena, Davies, Victor A., Cooper, Peter A., Mer, Mervyn and Lipman, Jeffrey (2019). A review of -multidrug-resistant Enterobacteriaceae in a neonatal unit in Johannesburg, South Africa. BMC Pediatrics, 19 (1) 320, 320. doi: 10.1186/s12887-019-1709-y

Dhaese, Sofie A.M., Thooft, Alexander D.J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2019). Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study. Journal of Critical Care, 52, 75-79. doi: 10.1016/j.jcrc.2019.04.013

T.P. Wan, Winnie, Guerra Valero, Yarmarly, Choi, Gordon Y.S., Ordóñez Mejia, Jenny L., Wallis, Steven C., Joynt, Gavin M., Lipman, Jeffrey, Gomersall, Charles D. and Roberts, Jason A. (2019). In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration. International Journal of Antimicrobial Agents, 54 (2), 261-264. doi: 10.1016/j.ijantimicag.2019.03.018

Ho, Kwok M., Holley, Anthony and Lipman, Jeffrey (2019). Vena Cava filters in severely-injured patients: one size does not fit all. Anaesthesia Critical Care and Pain Medicine, 38 (4), 305-307. doi: 10.1016/j.accpm.2019.07.003

Laupland, Kevin B., Tabah, Alexis, Kelway, Charlotte and Lipman, Jeffrey (2019). Does intermittent pneumatic compression PREVENT deep vein thrombosis in the ICU?. Anaesthesia Critical Care and Pain Medicine, 38 (4), 303-304. doi: 10.1016/j.accpm.2019.05.006

Koulenti, Despoina, Xu, Elena, Mok, Isaac Yin Sum, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019). Novel antibiotics for multidrug-resistant gram-positive microorganisms. Microorganisms, 7 (8), 270. doi: 10.3390/microorganisms7080270

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth, Corcoran, Tomas, Misur, Philip, Edibam, Cyrus, Baker, Ross I., Chamberlain, Jenny, Forsdyke, Claire and Rogers, Frederick B. (2019). A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 (4), 328-337. doi: 10.1056/NEJMoa1806515

Sumi, Chandra Datta, Heffernan, Aaron J., Lipman, Jeffery, Roberts, Jason A. and Sime, Fekade B. (2019). What antibiotic exposures are required to suppress the emergence of resistance for gram‑negative bacteria? A systematic review. Clinical Pharmacokinetics, 58 (11), 1407-1443. doi: 10.1007/s40262-019-00791-z

Weber, Nicholas, Jackson, Kathryn, McWhinney, Brett, Ungerer, Jacobus, Kennedy, Glen, Lipman, Jeffrey and Roberts, Jason A. (2019). Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia. Journal of Infection and Chemotherapy, 25 (7), 503-508. doi: 10.1016/j.jiac.2019.02.014

Economou, Caleb J. P., Xie, Jiao, Comadira, Gregory, Richards, Brent, Tallott, Mandy, Wallis, Steven C., Ordoñez, Jenny, Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International Journal of Antimicrobial Agents, 54 (3), 351-355. doi: 10.1016/j.ijantimicag.2019.06.027

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9

Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019). Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 (6) dkz069, 1662-1669. doi: 10.1093/jac/dkz069

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2). European Journal of Clinical Microbiology and Infectious Diseases, 38 (4), 649-649. doi: 10.1007/s10096-019-03518-x

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?. European Journal of Clinical Microbiology & Infectious Diseases, 38 (4), 637-647. doi: 10.1007/s10096-019-03486-2

De Backer, Daniel, Cecconi, Maurizio, Lipman, Jeffrey, Machado, Flavia, Myatra, Sheila Nainan, Ostermann, Marlies, Perner, Anders, Teboul, Jean-Louis, Vincent, Jean-Louis and Walley, Keith R. (2019). Challenges in the management of septic shock: a narrative review. Intensive Care Medicine, 45 (4), 420-433. doi: 10.1007/s00134-019-05544-x

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68. doi: 10.1016/s1441-2772(23)00582-3

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434

Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019). Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 (3), 211-224. doi: 10.1016/j.ijantimicag.2018.10.011

McCullough, James P.A., Lipman, Jeffrey and Presneill, Jeffrey J. (2018). The statistical curriculum within randomized controlled trials in critical illness. Critical Care Medicine, 46 (12), 1985-1990. doi: 10.1097/CCM.0000000000003380

Sakr, Yasser, Jaschinski, Ulrich, Wittebole, Xavier, Szakmany, Tamas, Lipman, Jeffrey, Namendys-Silva, Silvio A., Martin-Loeches, Ignacio, Leone, Marc, Lupu, Mary-Nicoleta and Vincent, Jean-Louis (2018). Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit. Open Forum Infectious Diseases, 5 (12), ofy313. doi: 10.1093/ofid/ofy313

Ballot, Daynia Elizabeth, Ramdin, Tanusha, White, Debbie Ann and Lipman, Jeffrey (2018). A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa. BMC Research Notes, 11 (1) 829, 829. doi: 10.1186/s13104-018-3946-9

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, 52 (4), 506-509. doi: 10.1016/j.ijantimicag.2018.07.008

Wong, Gloria, Briscoe, Scott, McWhinney, Brett, Ally, Mumtaz, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A (2018). Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. Journal of Antimicrobial Chemotherapy, 73 (11), 3087-3094. doi: 10.1093/jac/dky314

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018). The authors reply. Critical Care Medicine, 46 (7), e725-e726. doi: 10.1097/CCM.0000000000003164

Tsai, D., Stewart, P. C., Hewagama, S., Krishnaswamy, S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2018). Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis. Anaesthesia and Intensive Care, 46 (4), 374-380. doi: 10.1177/0310057X1804600405

Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018). New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 (7), 1-16. doi: 10.1080/17425255.2018.1484452

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016

Dhanani, J. A., Barnett, A. G., Lipman, J. and Reade, M. C. (2018). Strategies to reduce inappropriate laboratory blood test orders in intensive care are effective and safe: a before-and-after quality improvement study. Anaesthesia and Intensive Care, 46 (3), 313-320. doi: 10.1177/0310057X1804600309

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). Pharmacokinetics of intravenous posaconazole in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (6) e00242-18, e00242-18. doi: 10.1128/AAC.00242-18

Heffernan, A. J., Sime, F. B., Lipman, J. and Roberts, J. A. (2018). Individualising therapy to minimize bacterial multidrug resistance. Drugs, 78 (6), 621-641. doi: 10.1007/s40265-018-0891-9

Economou, Caleb J. P., Kielstein, Jan T., Czock, David, Xie, Jiao, Field, Jonathan, Richards, Brent, Tallot, Mandy, Visser, Adam, Koenig, Christina, Hafer, Carsten, Schmidt, Julius J., Lipman, Jeffrey and Roberts, Jason A. (2018). Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy. International Journal of Antimicrobial Agents, 52 (2), 151-157. doi: 10.1016/j.ijantimicag.2018.03.001

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057

Yadav, Rajbharan, Rogers, Kate E., Bergen, Phillip J., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling. Antimicrobial Agents and Chemotherapy, 62 (5) e00078, e00078-18. doi: 10.1128/AAC.00078-18

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269

Dahyot-Fizelier, Claire, Marchand, Sandrine and Lipman, Jeffrey (2018). Is augmented renal clearance the Holy Grail of antibiotic therapy failure in ventilator-acquired pneumonia?. Anaesthesia Critical Care & Pain Medicine, 37 (1), 5-6. doi: 10.1016/j.accpm.2017.12.003

Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018). Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 (2), 236-243. doi: 10.1097/CCM.0000000000002836

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023

Bergen, Phillip J., Bulitta, Jürgen B., Sime, Fekade B., Lipman, Jeffrey, McGregor, Megan J., Millen, Nada, Paterson, David L., Kirkpatrick, Carl M. J., Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 91 (1), 69-76. doi: 10.1016/j.diagmicrobio.2017.12.019

Tsai, D., Udy, A. A., Stewart, P. C., Gourley, S., Morick, N. M., Lipman, J. and Roberts, J. A. (2018). Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission. Anaesthesia and Intensive Care, 46 (1), 42-50. doi: 10.1177/0310057X1804600107

De Waele, Jan J., Akova, Murat, Antonelli, Massimo, Canton, Rafael, Carlet, Jean, De Backer, Daniel, Dimopoulos, George, Garnacho-Montero, José, Kesecioglu, Jozef, Lipman, Jeffrey, Mer, Mervyn, Paiva, José-Artur, Poljak, Mario, Roberts, Jason A., Rodriguez Bano, Jesus, Timsit, Jean-François, Zahar, Jean-Ralph and Bassetti, Matteo (2017). Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Medicine, 44 (2), 189-196. doi: 10.1007/s00134-017-5036-1

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030

Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2

Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17

de Prost, Nicholas, Lipman, Jeffrey and Mimoz, Olivier (2017). Therapeutic targets in necrotizing soft tissue infections. Intensive Care Medicine, 43 (11), 1717-1719. doi: 10.1007/s00134-017-4813-1

Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330

Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodriguez-Bano, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R. and Paterson, D.L. (2017). Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection, 23 (8), 533-541. doi: 10.1016/j.cmi.2016.10.023

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017). Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 (7) e016747, e016747. doi: 10.1136/bmjopen-2017-016747

Druery, Martha, Newcombe, Peter A., Cameron, Cate M. and Lipman, Jeffrey (2017). Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol. BMJ Open, 7 (6) e017545, e017545. doi: 10.1136/bmjopen-2017-017545

Badenes, Rafael, Oddo, Mauro, Suarez, Jose I., Antonelli, Massimo, Lipman, Jeffrey, Citerio, Giuseppe and Taccone, Fabio Silvio (2017). Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey. Critical Care, 21 (1) 159, 159. doi: 10.1186/s13054-017-1748-4

Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16

Poulakou, Garyfallia, Matthaiou, Dimitrios K., Bassetti, Matteo, Erdem, Hakan, Dimopoulos, George, Curcio, Daniel J., Carlet, Jean, Lipman, Jeffrey, Timsit, Jean‑François, Giamarellou, Helen, Arfaras-Melainis, Angelos and Rello, Jordi (2017). “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Medicine, 43 (8), 1164-1166. doi: 10.1007/s00134-017-4796-y

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022

Pretorius, Carel J., Reade, Michael C., Warnholtz, Chris, McWhinney, Brett, Phua, Meng Mei, Lipman, Jeffrey and Ungerer, Jacobus P. J. (2017). Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients. Clinica Chimica Acta, 466, 72-77. doi: 10.1016/j.cca.2017.01.012

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2017). Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection. Chest, 151 (3), 586-596. doi: 10.1016/j.chest.2016.10.057

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014

Kollef, Marin H., Bassetti, Matteo, Francois, Bruno, Burnham, Jason, Dimopoulos, George, Garnacho-Montero, Jose, Lipman, Jeffrey, Luyt, Charles‑Edouard, Nicolau, David P., Postma, Maarten J., Torres, Antonio, Welte, Tobias and Wunderink, Richard G. (2017). The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship. Intensive Care Medicine, 43 (9), 1-11. doi: 10.1007/s00134-017-4682-7

Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017). Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 (2), 331-336. doi: 10.1097/CCM.0000000000002210

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017). Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 (5), 221-226. doi: 10.1089/ars.2016.6845

Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W. and Roberts, Jason A. (2017). Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 (1) e01763-16, e01763-16. doi: 10.1128/AAC.01763-16

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328

Abdullah, Fareed, Adam, Sumaiya, Adams, Yasmin, Adhikari, Miriam, Ally, Riedwaan, Archer, Elize, Araújo, Márcio, Argent, Andrew, Ariffin, Affirul, Asombang, Akwi, Aucamp, Marina, Ballot, Daynia, Barron, Peter, Bekker, Wanda, Berry, Michael, Bhana, Arvin, Bhimma, Rajendra, Biko, Jack, Blecher, Evan, Blockman, Marc, Blumberg, Lucille, Both, Martin, Brink, Adrian, Brits, Hanneke, Britz, Russell, Bruijns, Stevan, Brezinski, Piotr, Buchmann, Eckhart, Butchart, Alex ... Farham, Bridget (2017). Thank you from HMPG and the editors. South African Medical Journal, 107 (12), 1045-1046. doi: 10.7196/SAMJ.2017.V107I12.12985

Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016). Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 56 (9), 1-12. doi: 10.1007/s40262-016-0495-z

Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 (2), 231-239. doi: 10.1097/QCO.0000000000000348

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 (12), 7402-7406. doi: 10.1128/AAC.01657-16

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (6), 748-752. doi: 10.1016/j.ijantimicag.2016.09.021

Playford, E. Geoffrey, Lipman, Jeffrey, Jones, Michael, Lau, Anna F., Kabir, Masrura, Chen, Sharon C. -A., Marriott, Deborah J., Seppelt, Ian, Gottlieb, Thomas, Cheung, Winston, Iredell, Jonathan R., McBryde, Emma S. and Sorrell, Tania C. (2016). Problematic dichotomization of risk for Intensive Care Unit (ICU)-acquired invasive candidiasis: results using a risk-predictive model to categorize 3 levels of risk from a multicenter prospective cohort of Australian ICU patients. Clinical Infectious Diseases, 63 (11), 1463-1469. doi: 10.1093/cid/ciw610

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (5), 542-546. doi: 10.1016/j.ijantimicag.2016.08.015

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35, 231-239. doi: 10.1016/j.jcrc.2016.06.022

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016). Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 (10), e923-e929. doi: 10.1097/CCM.0000000000001823

Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016). Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 (5), 311-312. doi: 10.1016/j.accpm.2016.08.002

Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016). Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 (10) dkw247, 2902-2908. doi: 10.1093/jac/dkw247

Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0

Perner, Anders, Gordon, Anthony C., de Backer, Daniel, Dimopoulos, George, Russell, James A., Lipman, Jeffrey, Jensen, Jens‑Ulrik, Myburgh, John, Singer, Mervyn, Bellomo, Rinaldo and Walsh, Timothy (2016). Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy. Intensive Care Medicine, 42 (12), 1-12. doi: 10.1007/s00134-016-4577-z

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Eley, Victoria, Callaway, Leonie, van Zundert, Andre, Lipman, Jeffrey and Gallois, Cindy (2016). Interpretation of care guidelines for obese women in labor: intergroup language and social identity. Journal of Language and Social Psychology, 36 (4), 388-414. doi: 10.1177/0261927X16668564

Eley, V. A., Callaway, L.K., Van Zundert, A. A. J., Lipman, J. and Gallois, C. (2016). Anaesthetists' experiences with the early labour epidural recommendation for obese parturients: a qualitative study. Anaesthesia and Intensive Care, 44 (5), 620-626. doi: 10.1177/0310057X1604400521

Eley, V. A., Van Zundert, A. A. J., Lipman, J. and Callaway, L. K. (2016). Anaesthetic management of obese parturients: what is the evidence supporting practice guidelines?. Anaesthesia and Intensive Care, 44 (5), 552-559. doi: 10.1177/0310057X1604400517

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016). Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 (9), 2509-2520. doi: 10.1093/jac/dkw153

Labeau, Sonia O., Rello, Jordi, Dimopoulos, George, Lipman, Jeffrey, Sarikaya, Aklime, Ozturk, Candan, Vandijck, Dominique M., Vogelaers, Dirk, Vandewoude, Koenraad and Blot, Stijn I. (2016). The value of e-learning for the prevention of healthcare-associated infections. Infection Control and Hospital Epidemiology, 37 (9), 1052-1059. doi: 10.1017/ice.2016.107

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.

Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 (240) 240, 240. doi: 10.1186/s13054-016-1426-y

Roger, Claire, Wallis, Steven C., Muller, Laurent, Saissi, Gilbert, Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2016). Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy. Antimicrobial Agents and Chemotherapy, 60 (8), 4901-4909. doi: 10.1128/AAC.00828-16

Cristallini, Stefano, Hites, Maya, Kabtouri, Hakim, Roberts, Jason A., Beumier, Marjorie, Cotton, Frederic, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis, Creteur, Jacques and Taccone, Fabio Silvio (2016). New regimen for continuous infusion of vancomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4750-4756. doi: 10.1128/AAC.00330-16

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4577-4584. doi: 10.1128/AAC.00531-16

Denny, Kerina Jane and Lipman, Jeffrey (2016). Bugs, genes, and the intensive care unit. Journal of Thoracic Disease, 8 (8), E788-E790. doi: 10.21037/jtd.2016.06.19

Ranganathan, Dwarakanathan, Naicker, Saiyuri, Wallis, Steven C., Lipman, Jeffrey, Ratanjee, Sharad K. and Roberts, Jason A. (2016). Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study). Peritoneal Dialysis International, 36 (4), 421-426. doi: 10.3747/pdi.2015.00062

Roberts, Darren M., Ranganathan, Dwarakanathan, Wallis, Steven C., Varghese, Julie M., Kark, Adrian, Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 36 (4), 415-420. doi: 10.3747/pdi.2015.00008

Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016). Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 (6), 1643-1650. doi: 10.1093/jac/dkw043

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 (6), 872-879. doi: 10.1002/bmc.3622

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238

Barbier, Francois, Lipman, Jeffrey and Bonten, Marc J. M. (2016). In 2035, will all bacteria be multidrug-resistant? No. Intensive Care Medicine, 42 (12), 1-4. doi: 10.1007/s00134-016-4348-x

Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016). Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 (7), 961-979. doi: 10.1586/17512433.2016.1172209

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016). Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 (4), 259-268. doi: 10.1016/j.ijantimicag.2016.01.009

Tong, Steven Y. C., Nelson, Jane, Paterson, David L., Fowler, Vance G., Jr., Howden, Benjamin P., Cheng, Allen C., Chatfield, Mark, Lipman, Jeffrey, Van Hal, Sebastian, O'Sullivan, Matthew, Robinson, James O., Yahav, Dafna, Lye, David and Davis, Joshua S. (2016). CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial. Trials, 17 (1) 170, 170. doi: 10.1186/s13063-016-1295-3

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6

Williams, Julian M., Greenslade, Jaimi H., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2016). Severity scores in emergency department patients with presumed infection: a prospective validation study. Critical Care Medicine, 44 (3), 539-547. doi: 10.1097/CCM.0000000000001427

Dodds, Michelle M., Frazer, Callum D., Lipman, Jeffrey and Reade, Michael (2016). Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine. Critical Care and Resuscitation, 18 (1), 59-61.

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

Woodruff, Trent M., Wu, Mike C.-L., Morgan, Michael, Bain, Nathan T., Jeanes, Angela, Lipman, Jeffrey, Ting, Michael J., Boyd, Andrew W., Taylor, Stephen M. and Coulthard, Mark G. (2016). EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability. Shock, 45 (2), 184-191. doi: 10.1097/SHK.0000000000000494

Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016). Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 (2) dkv349, 464-470. doi: 10.1093/jac/dkv349

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15

Williams, Julian M., Greenslade, Jaimi H., Dymond, Chelsea A., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffery (2016). Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study. European Journal of Emergency Medicine, 25 (2), 1-104. doi: 10.1097/MEJ.0000000000000419

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016). Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 (1), 206-214. doi: 10.1128/AAC.01543-15

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015). The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 (12) e0144740, e0144740. doi: 10.1371/journal.pone.0144740

McHugh, Leo, Seldon, Therese A., Brandon, Roslyn A., Kirk, James T., Rapisarda, Antony, Sutherland, Allison J., Presneill. Jeffrey J., Venter, Deon J., Lipman, Jeffrey, Thomas, Mervyn R., Klein Klouwenberg, Peter M.C., van Vught, Lonneke, Scicluna, Brendon, Bonten, Marc, Cremer, Olaf L., Schultz, Marcus J., van der Poll, Tom, Yager, Thomas D. and Brandon, Richard B. (2015). A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts. PLoS Medicine, 12 (12) e1001916, e1001916. doi: 10.1371/journal.pmed.1001916

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate ... Paul, Sanjoy (2015). A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 (11), 1298-1305. doi: 10.1164/rccm.201505-0857OC

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015). Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 (12), 3178-3183. doi: 10.1093/jac/dkv201

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

Wong, Wai-Tat, Choi, Gordon, Gomersall, Charles D. and Lipman, Jeffrey (2015). To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt. Current Opinion in Pharmacology, 24, 68-78. doi: 10.1016/j.coph.2015.07.003

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 (5), 412-420. doi: 10.1097/MCC.0000000000000229

Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015). Understanding PK/PD. Intensive Care Medicine, 42 (11), 1797-1800. doi: 10.1007/s00134-015-4032-6

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143

Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015). Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 (5), 594-599. doi: 10.1177/0310057X1504300507

Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 (3), 249-253. doi: 10.1016/j.ijantimicag.2015.04.013

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015). A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (8), 4689-4694. doi: 10.1128/AAC.00409-15

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422

Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060

Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015). Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 (4), 367-375. doi: 10.1016/j.ijantimicag.2015.06.016

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017

Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A., Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 46 (1), 39-44. doi: 10.1016/j.ijantimicag.2015.02.014

Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015). Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 (6), 647-651. doi: 10.1016/j.ijantimicag.2015.01.015

Finfer, Simon, Chittock, Dean, Li, Yang, Foster, Denise, Dhingra, Vinay, Bellomo, Rinaldo, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William, Heyland, Daren, Higgins, Alisa, McArthur, Colin, Mitchell, Imogen, Myburgh, John, Robinson, Bruce, Ronco, Juan, Blair, Deborah, McArthur, Colin, Mitchell, Imogen, Norton, Robyn, Potter, Julie, Chittock, Dean, Dhingra, Vinay, Foster, Denise, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William ... Wood, Gordon (2015). Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Medicine, 41 (6), 1037-1047. doi: 10.1007/s00134-015-3757-6

Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 (5), E154-E155. doi: 10.1097/CCM.0000000000000952

Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015). How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 (1), 92-103. doi: 10.1016/j.diagmicrobio.2015.01.013

De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015). Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 (5), 969-969. doi: 10.1007/s00134-015-3772-7

Joynt, Gavin M., Lipman, Jeffrey, Hartog, Christiane, Guidet, Bertrand, Paruk, Fathima, Feldman, Charles, Kissoon, Niranjan and Sprung, Charles L. (2015). The Durban World Congress Ethics Round Table IV: Health care professional end-of-life decision making. Journal of Critical Care, 30 (2), 224-230. doi: 10.1016/j.jcrc.2014.10.011

Lau, Anna F, Kabir, Masrura, Chen, Sharon C-A, Playford, E. Geoffrey, Marriott, Deborah J, Jones, Michael, Lipman, Jeffrey, McBryde, Emma, Gottlieb, Thomas, Cheung, Winston, Seppelt, Ian, Iredell, Jonathan and Sorrella, Tania C (2015). Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: Development and evaluation of a simple, standard protocol. Journal of Clinical Microbiology, 53 (4), 1324-1330. doi: 10.1128/JCM.03239-14

Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8

Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015). Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (3), 1411-1417. doi: 10.1128/AAC.04001-14

Sakr, Yasser, Moreira, Cora L., Rhodes, Andrew, Ferguson, Niall D., Kleinpell, Ruth, Pickkers, Peter, Kuiper, Michael A., Lipman, Jeffrey, Vincent, Jean-Louis and Extended Prevalence of Infection in Intensive Care Study Investigators (2015). The impact of hospital and ICU organizational factors on outcome in critically ill patients: results from the Extended Prevalence of Infection in Intensive Care Study. Critical Care Medicine, 43 (3), 519-526. doi: 10.1097/CCM.0000000000000754

Paratz, Jennifer D., Lipman, Jeffrey and Boots, Robert J. (2015). Serum markers of sepsis in burn patients: it takes more to convince! Reply. Critical Care Medicine, 43 (3), E101-E101. doi: 10.1097/CCM.0000000000000868

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3

Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015). Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 (2), 528-533. doi: 10.1093/jac/dku413

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490

Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y

Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 (1) 24, 24.1-24.8. doi: 10.1186/s13063-014-0541-9

O'Callaghan D., Holley A. and Lipman J. (2015). From the intensive care bed: we need to hear and listen. Intensive Care Medicine, 41 (5), 921-922. doi: 10.1007/s00134-014-3614-z

De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015). Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 (5) 4517, 461-463. doi: 10.1016/j.ijantimicag.2015.01.007

Udy A.A., De Waele J.J. and Lipman J. (2015). Augmented renal clearance and therapeutic monitoring of β-lactams. International Journal of Antimicrobial Agents, 45 (4), 331-333. doi: 10.1016/j.ijantimicag.2014.12.020

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 (1), 41-45. doi: 10.1016/j.ijantimicag.2014.09.009

Vermeir, Julie, Holley, Anthony and Lipman, Jeffrey (2015). “Not out of the woods”—a wife’s perspective: bedside communication. Intensive Care Medicine, 42 (3), 446-447. doi: 10.1007/s00134-015-4035-3

Ramanan, Mahesh, Lipman, Jeffrey, Shorr, Andrew and Shankar, Aparna (2015). A meta-analysis of ventriculostomy-associated cerebrospinal fluid infections. Bmc Infectious Diseases, 15 (1) 712, 3. doi: 10.1186/s12879-014-0712-z

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831

Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014). The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 (6) 565, 1-9. doi: 10.1186/s13054-014-0565-2

Paruk, Fathima, Kissoon, Niranjan, Hartog, Christiane S., Feldman, Charles, Hodgson, Eric R., Lipman, Jeffrey, Guidet, Bertrand, Du, Bin, Argent, Andrew and Sprung, Charles L. (2014). The Durban World Congress Ethics Round Table Conference Report: III. Withdrawing Mechanical ventilation-the approach should be individualized. Journal of Critical Care, 29 (6), 902-907. doi: 10.1016/j.jcrc.2014.05.022

Guidet, Bertrand, Hodgson, Eric, Feldman, Charles, Paruk, Fathima, Lipman, Jeffrey, Koh, Younsuck, Vincent, Jean Louis, Azoulay, Elie and Sprung, Charles L. (2014). The Durban World Congress Ethics Round Table Conference Report: II. Withholding or withdrawing of treatment in elderly patients admitted to the intensive care unit. Journal of Critical Care, 29 (6), 896-901. doi: 10.1016/j.jcrc.2014.08.004

Sprung, Charles L., Paruk, Fathima, Kissoon, Niranjan, Hartog, Christiane S., Lipman, Jeffrey, Du, Bin, Argent, Andrew, Hodgson, R. Eric, Guidet, Bertrand, Groeneveld, A. B. Johan and Feldman, Charles (2014). The Durban World Congress Ethics Round Table conference report: I. Differences between withholding and withdrawing life-sustaining treatments. Journal of Critical Care, 29 (6), 890-895. doi: 10.1016/j.jcrc.2014.06.022

De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014). Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 (12), 1302-1309.

Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014). Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 (12), 2527-2536. doi: 10.1097/CCM.0000000000000514

Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014). Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 (657) 657, 1-9. doi: 10.1186/s13054-014-0657-z

Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014). How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 (288) 288, 1-11. doi: 10.1186/1471-2334-14-288

Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014). Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 (3), 243-260. doi: 10.1007/s40262-014-0209-3

Adnan, S., Ratnam, S., Kumar, S., Paterson, D., Lipman, J., Roberts, J. and Udy, A. A. (2014). Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit. Anaesthesia And Intensive Care, 42 (6), 715-722. doi: 10.1177/0310057X1404200606

Blot, Stijn I., Pea, Federico and Lipman, Jeffrey (2014). The effect of pathophysiology on pharmacokinetics in the critically ill patient - concepts appraised by the example of antimicrobial agents. Advanced Drug Delivery Reviews, 77, 3-11. doi: 10.1016/j.addr.2014.07.006

Talekar, C. R., Udy, A. A., Boots, R. J., Lipman, J. and Cook, D. (2014). Tracheal cuff pressure monitoring in the ICU: a literature review and survey of current practice in Queensland. Anaesthesia and intensive care, 42 (6), 761-770. doi: 10.1177/0310057X1404200612

Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014). Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 (10), 2797-2803. doi: 10.1093/jac/dku195

Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 (10), 1380-1384. doi: 10.1177/1060028014540610

Hanberger, Hakan, Antonelli, Massimo, Holmbom, Martin, Lipman, Jeffrey, Pickkers, Peter, Leone, Marc, Rello, Jordi, Sakr, Yasser, Walther, Sten M., Vanhems, Philippe, Vincent, Jean-Louis, for the EPIC II Group of Investigators and Koulenti, D. (2014). Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels. BMC Infectious Diseases, 14 (513) 513. doi: 10.1186/1471-2334-14-513

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403

Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014). Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 (5), 409-415. doi: 10.1016/j.ijantimicag.2014.07.001

De Waele, Jan J., Rello, Jordi, Anzueto, Antonio, Moreno, Rui, Lipman, Jeffrey, Sakr, Yasser, Pickkers, Peter, Leone, Marc, Ferguson, Andrew, Oud, Lavi and Vincent, Jean-Louis (2014). Infections and use of antibiotics in patients admitted for severe acute pancreatitis: Data from the epic II study. Surgical Infections, 15 (4), 394-398. doi: 10.1089/sur.2012.228

Udy, Andrew A., Baptista, João P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Boots, Robert J. and Lipman, Jeffrey (2014). The authors reply. Critical Care Medicine, 42 (8), e602-e603. doi: 10.1097/CCM.0000000000000465

De Waele, Jan, Lipman, Jeffrey, Sakr, Yasser, Marshall, John C., Vanhems, Philippe, Barrera Groba, Casiano, Leone, Marc and Vincent, Jean-Louis (2014). Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome. BMC Infectious Diseases, 14 (420) 420, 1-17. doi: 10.1186/1471-2334-14-420

Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 (7), 1640-1650. doi: 10.1097/CCM.0000000000000317

Paratz, Jennifer D., Stockton, Kellie, Paratz, Elizabeth D., Blot, Stijn, Muller, Michael, Lipman, Jeffrey and Boots, Robert J. (2014). Burn resuscitation - hourly urine output vs alternative endpoints: a systematic review. Shock, 42 (4), 295-306. doi: 10.1097/SHK.0000000000000204

Dulhunty, Joel M., Starr, Therese, Bellomo, Rinaldo and Lipman, Jeffrey (2014). Randomised controlled trials: the long hard climb to the summit - is there another way in the 21st century?. Critical Care and Resuscitation, 16 (2), 87-89.

Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 (6), 572-573. doi: 10.1016/j.ijantimicag.2014.03.001

Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014). Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 (3) R99, 1-11. doi: 10.1186/cc13874

Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564

Vincent, Jean-Louis, Marshall, John C., Namendys-Silva, Silvo A., Francois, Bruno, Martin-Loeches, Ignacio, Lipman, Jeffrey, Reinhart, Konrad, Antonelli, Massimo, Pickkers, Peter, Njimi, Hassane, Jimenez, Edgar and Sakr, Yasser (2014). Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit. The Lancet Respiratory Medicine, 2 (5), 380-386. doi: 10.1016/S2213-2600(14)70061-X

Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014). The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 (1), 77-84. doi: 10.1016/j.diagmicrobio.2014.01.015

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 (8), 1072-1083. doi: 10.1093/cid/ciu027

Bellomo, Rinaldo, Cass, Alan, Cole, Louise, Finfer, Simon, Gallagher, Martin, Lee, Janne, Lo, Serigne, McArthur, Colin, McGuinness, Shay, Myburgh, John, Norton, Robyn, Scheinkestel, Carlos, The RENAL Study Investigators, Lipman, Jeffrey and Boots, Robert (2014). Calorie intake and patient outcomes in severe acute kidney injury: Findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial. Critical Care, 18 (2) R45, 1-11. doi: 10.1186/cc13767

Thomas, Peter, Paratz, Jennifer and Lipman, Jeffrey (2014). Seated and semi-recumbent positioning of the ventilated intensive care patient - effect on gas exchange, respiratory mechanics and hemodynamics. Heart and Lung: Journal of Acute and Critical Care, 43 (2), 105-111. doi: 10.1016/j.hrtlng.2013.11.011

Gallagher M., Cass A., Bellomo R., Finfer S., Gattas D., Lee J., Lo S., McGuinness S., Myburgh J., Parke R., Rajbhandari D., Mitchell I., Taylor E., Whyte R., Raza A., Nand K., Sara T., Millis D., Wong H., Harrigan P., Hardie M., Whitaker D., Bhonagiri D., Micallef S., Ellem K., Lintott M., Cole L., Cuzner C., Weisbrodt L. ... D'Haeseleer S. (2014). Long-Term Survival and Dialysis Dependency Following Acute Kidney Injury in Intensive Care: Extended Follow-up of a Randomized Controlled Trial. PLoS Medicine, 11 (2) e1001601, 1-13. doi: 10.1371/journal.pmed.1001601

Udy, Andrew A., Baptista, Joao P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Wockner, Leesa, Boots, Robert J. and Lipman, Jeffrey (2014). Augmented renal clearance in the ICU: Results of a Multicenter observational study of renal function in critically ill patients with normal plasma Creatinine concentrations. Critical Care Medicine, 42 (3), 520-527. doi: 10.1097/CCM.0000000000000029

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units. Nephrology, 19 (8), 507-512. doi: 10.1111/nep.12276

Paratz, Jennifer D., Lipman, Jeffrey, Boots, Robert J., Muller, Michael J. and Paterson, David L. (2014). A new marker of sepsis post burn injury?. Critical Care Medicine, 42 (9), 2029-2036. doi: 10.1097/CCM.0000000000000400

Escobar, Leslie, Andresen, Max, Downey, Patricio, Gai, Maria Nella, Regueira, Tomas, Borquez, Tamara, Lipman, Jeffrey and Roberts, Jason A. (2014). Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration. International Journal of Antimicrobial Agents, 44 (2), 163-167. doi: 10.1016/j.ijantimicag.2014.03.009

De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014). Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 (9), 1340-1351. doi: 10.1007/s00134-014-3403-8

Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014). Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 (5), 423-430. doi: 10.1016/j.ijantimicag.2014.01.023

Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 (6), 3533-3537. doi: 10.1128/AAC.02340-14

Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014). Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 (6), 498-509. doi: 10.1016/S1473-3099(14)70036-2

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014). Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 (5), 581-595. doi: 10.1586/14787210.2014.902308

Udy, Andrew A., Joynt, Gavin M. and Lipman, Jeffrey (2014). The authors reply. Critical Care Medicine, 42 (10), e675-e676. doi: 10.1097/CCM.0000000000000532

Varghese, Julie M., Jarrett, Paul, Boots, Robert J., Kirkpatrick, Carl M. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 43 (4), 343-348. doi: 10.1016/j.ijantimicag.2014.01.009

Roberts, Jason A., Udy, Andrew A., Bulitta, Juergen B., Stuart, Janin, Jarrett, Paul, Starr, Therese, Lassig-Smith, Melissa, Roberts, Natasha A., Dunlop, Rachel, Hayashi, Yoshiro, Wallis, Steven C. and Lipman, Jeffrey (2014). Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 69 (9) dku177, 2508-2516. doi: 10.1093/jac/dku177

Zoltan, Horvoelgyi, Eva, Kiss and Etelka, Tombacz (2014). Preface. Periodica Polytechnica-Chemical Engineering, 58, 1-1. doi: 10.1007/978-981-10-5336-8

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013). Clinical implications of antibiotic pharmacokinetic principles in the critically ill. Intensive Care Medicine, 39 (12), 2070-2082. doi: 10.1007/s00134-013-3088-4

Paratz, Jennifer and Lipman, Jeffrey (2013). B-type natriuretic peptide: not just a heart throb. A & A Case Reports, 1 (4), 59-61. doi: 10.1097/ACC.0b013e31829737ab

Udy, Andrew A., Morton, Fraser J. A., Nguyen-Pham, Sallyanne, Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Dunlop, Rachel, Starr, Therese, Boots, Robert J. and Lipman, Jeffrey (2013). A comparison of CKD-EPI estimated glomerular filtration rate and measured creatinine clearance in recently admitted critically ill patients with normal plasma creatinine concentrations. BMC Nephrology, 14 (1) 250, 250. doi: 10.1186/1471-2369-14-250

Goh, H. M. Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi, Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey and Schembri, Mark A. (2013). Molecular analysis of the Acinetobacter baumannii biofilm-associated protein. Applied and Environmental Microbiology, 79 (21), 6535-6543. doi: 10.1128/AEM.01402-13

Adnan, Syamhanin, Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2013). Ampicillin/sulbactam: Its potential use in treating infections in critically ill patients. International Journal of Antimicrobial Agents, 42 (5), 384-389. doi: 10.1016/j.ijantimicag.2013.07.012

Moriel, Danilo G., Beatson, Scott A., Wurpel, Daniël J., Lipman, Jeffrey, Nimmo, Graeme R., Paterson, David L. and Schembri, Mark A. (2013). Identification of novel vaccine candidates against multidrug-resistant Acinetobacter baumannii. PLoS ONE, 8 (10) e77631, e77631.1-e77631.9. doi: 10.1371/journal.pone.0077631

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013). What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 (4), 289-293. doi: 10.1016/j.ijantimicag.2013.05.018

Rello, Jordi and Lipman, Jeffrey (2013). Antibiotic prescription for respiratory tract infections in ventilated patients: where are we heading?. Intensive Care Medicine, 39 (9), 1644-1646. doi: 10.1007/s00134-013-2983-z

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Udy, Andrew A., Paul, Sanjoy K. and Lipman, Jeffrey (2013). A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study. Critical Care and Resuscitation, 15 (3), 179-185.

Putt, M. T., Udy, A. A., Jarrett, P., Martin, J., Hennig, S., Salmon, N., Lipman, J. and Roberts, J. A. (2013). Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels?. Anaesthesia and Intensive Care, 41 (5), 602-609. doi: 10.1177/0310057x1304100505

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L. and Lipman, Jeffrey (2013). Reply to Soman et al. Clinical Infectious Diseases, 57 (2), 323-324. doi: 10.1093/cid/cit201

Pletz, Mathias W. and Lipman, Jeffrey (2013). Clinical measures for increased creatinine clearances and suboptimal antibiotic dosing. Intensive Care Medicine, 39 (7), 1322-1324. doi: 10.1007/s00134-013-2918-8

Adnan, Syamhanin, Li, Janice Xuanhui, Wallis, Steven C., Rudd, Michael, Jarrett, Paul, Paterson, David L., Lipman, Jeffrey, Udy, Andrew A. and Roberts, Jason A. (2013). Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains. International Journal of Antimicrobial Agents, 42 (1), 90-93. doi: 10.1016/j.ijantimicag.2013.02.023

Udy, Andrew A., Covajes, Cecilia, Taccone, Fabio Silvio, Jacobs, Frederique, Vincent, Jean-Louis, Lipman, Jeffrey and Roberts, Jason A. (2013). Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?. International Journal of Antimicrobial Agents, 41 (6), 564-568. doi: 10.1016/j.ijantimicag.2013.01.018

Carlier, Mieke, Carrette, Sofie, Roberts, Jason A., Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C. and De Waele, Jan J. (2013). Meropenem and piperacillin/tazobactam prescribing in critically ill patients: Does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?. Critical Care, 17 (3) R84, R84.1-R84.9. doi: 10.1186/cc12705

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013). How should we dose antibiotics for pneumonia in the ICU?. Current Opinions in Infectious Diseases, 26 (2), 189-195. doi: 10.1097/QCO.0b013e32835d19e0

Hayashi, Yoshiro, Morisawa, Kenichiro, Klompas, Michael, Jones, Mark, Bandeshe, Hiran, Boots, Robert, Lipman, Jeffrey and Paterson, David L. (2013). Towards improved surveillance: the impact of ventilator-associated complications (VAC) on length of stay and antibiotic use in patients in intensive care units. Clinical Infectious Diseases, 56 (5), 471-477. doi: 10.1093/cid/cis926

Roberts, Jason and Lipman, Jeffrey (2013). Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance and decreased bacterial susceptibility. Critical Care Medicine, 41 (2), 489-495. doi: 10.1097/CCM.0b013e31826ab4c4

Hayashi, Yoshiro, Lipman, Jeffrey, Udy, Andrew A., Ng, Mandy, McWhinney, Brett, Ungerer, Jacobus, Lust, Karin and Roberts, Jason A. (2013). β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia. International Journal of Antimicrobial Agents, 41 (2), 162-166. doi: 10.1016/j.ijantimicag.2012.10.002

Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2013). Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations?. Antimicrobial Agents and Chemotherapy, 57 (12), 6165-6170. doi: 10.1128/AAC.00951-13

Udy, Andrew A., Roberts, Jason A., Shorr, Andrew F., Boots, Robert J. and Lipman, Jeffrey (2013). Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients. Critical Care, 17 (1) R35, R35.1-R35.9. doi: 10.1186/cc12544

Beumier, Marjorie, Roberts, Jason A., Kabtouri, Hakim, Hites, Maya, Cotton, Frederic, Wolff, Fleur, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis and Taccone, Fabio Silvio (2013). A new regimen for continuous infusion of vancomycin during continuous renal replacement therapy. Journal of Antimicrobial Chemotherapy, 68 (12) dkt261, 2859-2865. doi: 10.1093/jac/dkt261

Carlier, Mieke, Noe, Michael, De Waele, Jan J., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2013). Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients. Journal of Antimicrobial Chemotherapy, 68 (11) dkt240, 2600-2608. doi: 10.1093/jac/dkt240

Ranganathan, Dwarakanathan, John, George T., Healy, Helen, Roberts, Matthew J., Fassett, Robert G., Lipman, Jeffrey, Kubler, Paul, Ungerer, Jacobus, McWhinney, Brett C., Lim, Aaron, Purvey, Megan, Reyaldeen, Reza and Roberts, Jason A. (2013). A protocol for the pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN): An open-label, randomised controlled trial. BMJ Open, 3 (8) e003511, e003511. doi: 10.1136/bmjopen-2013-003511

Roberts, Jason, Pea, Federico and Lipman, Jeffrey (2013). The clinical relevance of plasma protein binding changes. Clinical Pharmacokinetics, 52 (1), 1-8. doi: 10.1007/s40262-012-0018-5

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Haﬁz, Lipman, Jeffrey and Roberts, Jason A. (2013). Defining antibiotic dosing in lung infections. Clinical Pulmonary Medicine, 20 (3), 121-128. doi: 10.1097/CPM.0b013e31828fc646

Dulhunty, Joel M., Roberts, Jason A., Webb, Joshua S., Webb, Steve A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David and Lipman, Jeffrey (2013). Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicentre double-blind, randomised controlled trial. Clinical Infectious Diseases, 56 (2), 236-244. doi: 10.1093/cid/cis856

Smith, Nicholas L., Freebairn, Ross C., Park, Michael A. J., Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2012). Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime. Critical Care and Resuscitation, 14 (4), 312-315.

Myburgh, John A., Finfer, Simon, Bellomo, Rinaldo, Billot, Lauren, Cass, Alan, Gattas, David, Glass, Parisa, Lipman, Jeffrey, Liu, Bette, McArthur, Coline, McGuinness, Shay, Rajbhandari, Dorrilyn, Taylor, Colman B., Webb, Steven A. R., for the CHEST Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group and Reade, Michael (2012). Hydroxyethyl starch or saline for fluid resuscitation in intensive care. New England Journal of Medicine, 367 (20), 1901-1911. doi: 10.1056/NEJMoa1209759

Briscoe, Scott E., McWhinney, Brett C., Lipman, Jeffrey, Roberts, Jason A. and Ungerer, Jacobus P. J. (2012). A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 907, 178-184. doi: 10.1016/j.jchromb.2012.09.016

Jamal, Janattul-Ain, Economou, Caleb J. P., Lipman, Jeffrey and Roberts, Jason A. (2012). Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation. Current Opinion in Critical Care, 18 (5), 460-471. doi: 10.1097/MCC.0b013e32835685ad

Ostrowski, J., Paterson, D. L., Lipman, J. and Udy, A. A. (2012). Blood culture collection in patients with acute kidney injury receiving renal replacement therapy: an observational study. Anaesthesia and Intensive Care, 40 (5), 813-819. doi: 10.1177/0310057X1204000509

Young, Paul, Hodgson, Carol, Dulhunty, Joel, Saxena, Manoj, Bailey, Michael, Bellomo, Rinaldo, Davies, Andrew, Finfer, Simon, Kruger, Peter, Lipman, Jeffrey, Myburgh, John, Peake, Sandra, Seppelt, Ian, Streat, Stephen, Tate, Rhiannon, Webb, Steven and The ANZICS Clinical Trials Group (2012). End points for phase II trials in intensive care: recommendations from the Australian and New Zealand Clinical Trials Group consensus panel meeting. Critical Care and Resuscitation, 14 (3), 211-215.

Boots, R. J., Singh, S. J. and Lipman, J. (2012). The tyranny of distance: telemedicine for the critically ill in rural Australia. Anaesthesia and Intensive Care, 40 (5), 871-874. doi: 10.1177/0310057X1204000517

Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012). Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 (1) 37, 37. doi: 10.1186/2110-5820-2-37

Patel, Bhavik M., Paratz, Jennifer D., Mallet, Anthony, Lipman, Jeffrey, Rudd, Michael, Muller, Michael J., Paterson, David L. and Roberts, Jason A. (2012). Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns, 38 (5), 685-690. doi: 10.1016/j.burns.2011.12.018

Varghese, Julie M., Roberts, Jason A., Wallis, Steven C., Boots, Robert J., Healy, Helen, Fassett, Robert G., Lipman, Jeffrey and Ranganathan, Dwarakanathan (2012). Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study). Clinical Journal of the American Society of Nephrology, 7 (8), 1249-1256. doi: 10.2215/CJN.12211211

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35

Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012). DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 (1) 152, 152.1-152.7. doi: 10.1186/1471-2334-12-152

Udy, A. A., Altukroni, M., Jarrett, P., Roberts, J. A. and Lipman, J. (2012). A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill. Anaesthesia and Intensive Care, 40 (4), 631-637. doi: 10.1177/0310057X1204000408

Udy, Andrew A., Varghese, Julie M., Altukroni, Mahdi, Briscoe, Scott, McWhinney, Brett C., Ungerer, Jacobus P., Lipman, Jeffrey and Roberts, Jason A. (2012). Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations. Chest, 142 (1), 30-39. doi: 10.1378/chest.11-1671

Roberts, Jason A. and Lipman, Jeffrey (2012). Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling. Clinical Infectious Diseases, 54 (12), 1727-1729. doi: 10.1093/cid/cis311

Ginn, Andrew N., Wiklendt, Agnieszka M., Gidding, Heather F., George, Narelle, O'Driscoll, James S., Partridge, Sally R., O'Toole, Brian I., Perri, Rita A., Faoagali, Joan, Gallagher, John E., Lipman, Jeffrey and Iredell, Jonathan R. (2012). The ecology of antibiotic use in the ICU: Homogeneous prescribing of cefepime but not tazocin selects for antibiotic resistant infection. Plos One, 7 (6) e38719, e38719.1-e38719.10. doi: 10.1371/journal.pone.0038719

Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012). Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 (3), 228-238. doi: 10.2174/157339812800493232

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 (6), 489-496. doi: 10.1111/j.1440-1681.2012.05715.x

Udy, Andrew A., Roberts, Jason A., De Waele, Jan J., Paterson, David L. and Lipman, Jeffrey (2012). What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International Journal of Antimicrobial Agents, 39 (6), 455-457. doi: 10.1016/j.ijantimicag.2012.02.010

Grewal, J. P., Singh, J. S. and Lipman, J. (2012). Methanol: don't forget the ethanol. Anaesthesia and Intensive Care, 40 (3), 560-561.

Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553

Patel, Bhavik M., Paratz, Jennifer, See, Natalie C., Muller, Michael J., Rudd, Michael, Paterson, David, Briscoe, Scott E., Ungerer, Jacobus, McWhinney, Brett C., Lipman, Jeffrey and Roberts, Jason A. (2012). Therapeutic drug monitoring of beta-lactam antibiotics in burns patients-A one-year prospective study. Therapeutic Drug Monitoring, 34 (2), 160-164. doi: 10.1097/FTD.0b013e31824981a6

Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Robert and Lipman, Jeffrey (2012). Review article: Part two: Goal-directed resuscitation - Which goals? Perfusion targets. Emergency Medicine Australasia, 24 (2), 127-135. doi: 10.1111/j.1742-6723.2011.01515.x

Roberts, Jason A., Joynt, Gavin M., Choi, Gordon Y.S., Gomersall, Charles D. and Lipman, Jeffrey (2012). How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics. International Journal of Antimicrobial Agents, 39 (3), 187-192. doi: 10.1016/j.ijantimicag.2011.11.002

Myburgh, John, Li, Qiang, Heritier, Stephane, Dan, Arina, Glass, Parisa, McGuinness, S., Bellomo, R. , Fletcher, J., Poojara, L. , Ellem, K. , Mitchell, I. , Henderson, S. , Milliss, D. , Ihle, B., Haji, K., de Keulenaer, B., Cattigan, C. , Harrigan, P. , Parr, M., Presneill, J., Seppelt, I. , Liang, J., Duke, G., Shehabi, Y., Boots, R., Cooper, D., Finfer, S., Gattas, D., Myburgh, J. ... Willenberg, L. (2012). Statistical analysis plan for the Crystalloid Versus Hydroxyethyl Starch Trial (CHEST). Critical Care and Resuscitation, 14 (1), 44-52.

Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Roberts and Lipman, Jeffrey (2012). Review article: Part one: Goal-directed resuscitation - Which goals? Haemodynamic targets. Emergency Medicine Australasia, 24 (1), 14-22. doi: 10.1111/j.1742-6723.2011.01516.x

Adnan, Syamhanin, Paterson, David, Lipman, Jeffrey, Kumar, Suresh, Li, Janice, Rudd, Michael J and Roberts, Jason (2012). Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: A structured review. Surgical Infections, 13 (1), 9-17. doi: 10.1089/sur.2011.046

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013

Lonsdale, Dagan O., Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2012). Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations. Journal of Neurosurgery, 118 (2), 297-301. doi: 10.3171/2012.10.JNS12883

Abdul-Aziz, Mohd Hafiz, Staatz, C. E., Kirkpatrick, C. M. J., Lipman, J. and Roberts, J. A. (2012). Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics. Minerva Anestesiologica, 78 (1), 94-104.

Li, Janice, Udy, Andrew A., Kirkpatrick, Carl M.J., Lipman, Jeffrey and Roberts,Jason A. (2012). Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study. International Journal of Antimicrobial Agents, 39 (1), 69-72. doi: 10.1016/j.ijantimicag.2011.08.017

Patel, Kashyap, Roberts, Jason A., Lipman, Jeffrey, Tett, Susan E., Deldot, Megan E. and Kirkpatrick, Carl M. (2011). Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration - using Monte Carlo Simulations to predict doses for specified pharmacodynamic targets. Antimicrobial Agents and Chemotherapy, 55 (12), 5868-5873. doi: 10.1128/AAC.00424-11

Boots, Robert James, Singh, Sunil, Terblanche, Morne, Widdicombe, Neil and Lipman, Jeffery (2011). Remote care by telemedicine in the ICU: Many models of care can be effective. Current Opinion in Critical Care, 17 (6), 634-640. doi: 10.1097/MCC.0b013e32834a789a

Hosein, Shaun, Udy, Andrew A. and Lipman, Jeffrey (2011). Physiological changes in the critically ill patient with sepsis. Current Pharmaceutical Biotechnology, 12 (12), 1991-1995. doi: 10.2174/138920111798808248

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11

Lipman, J., Udy, A. and Roberts, Jason (2011). Do we understand the impact of altered physiology, consequent interventions and resultant clinical scenarios in the intensive care unit? The antibiotic story. Anaesthesia and Intensive Care, 39 (6), 999-1000. doi: 10.1177/0310057x1103900602

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309

Dulhunty, Joel, Boots, Robert J., Paratz, Jennifer D. and Lipman, Jeffrey (2011). Determining authorship in multicentre trials: A systematic review. Acta anaesthesiologica scandinavica, 55 (9), 1037-1043. doi: 10.1111/j.1399-6576.2011.02477.x

Hanberger, Hakan, Walther, Sten, Leone, Marc, Barie, Philip S., Rello, Jordi, Lipman, Jeffrey, Marshall, John C., Anzueto, Antonio, Sakr, Yasser, Pickkers, Peter, Felleiter, Peter, Engoren, Milo, Vincent, Jean-Louis and Epic II Group of Investigators (2011). Increased mortality associated with meticillin-resistant Staphylococcus aureus (MRSA) infection in the Intensive Care Unit: Results from the EPIC II study. International Journal of Antimicrobial Agents, 38 (4), 331-335. doi: 10.1016/j.ijantimicag.2011.05.013

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2011). Implications of augmented renal clearance in critically ill patients. Nature Reviews Nephrology, 7 (9), 539-543. doi: 10.1038/nrneph.2011.92

Boots, Robert J., Lipman, Jeffrey, Lassig-Smith, Melissa, Stephens, DP, Thomas, J., Shehabi, Y., Bass, F., Anthony, A., Long, D., Seppelt, I.M., Weisbrodt, L., Erickson, S., Beca, J., Sherring, C., McGuiness, S., Parke, R., Stachowski, E.R., Boyd, R. and Howe, B. (2011). Experience with high frequency oscillation ventilation during the 2009 H1N1 influenza pandemic in Australia and New Zealand. Anaesthesia and Intensive Care, 39 (5), 837-846. doi: 10.1177/0310057x1103900507

Martin, Jennifer H., Fay, Michael F., Udy, Andrew, Roberts, Jason, Kirkpatrick, Carl, Ungerer, Jacobus and Lipman, Jeffrey (2011). Pitfalls of using estimations of glomerular filtration rate in an intensive care population. Internal Medicine Journal, 41 (7), 537-543. doi: 10.1111/j.1445-5994.2009.02160.x

Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew A., Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2011). Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens. Antimicrobial Agents and Chemotherapy, 55 (6), 2704-2709. doi: 10.1128/AAC.01708-10

Baba, H., Nimmo, G. R., Allworth, A. M., Boots, R. J., Hayashi, Y., Lipman, J. and Paterson, D. L. (2011). The role of surveillance cultures in the prediction of susceptibility patterns of Gram-negative bacilli in the intensive care unit. European Journal of Clinical Microbiology and Infectious Diseases, 30 (6), 739-744. doi: 10.1007/s10096-010-1146-1

Baptista, Joao P., Udy, Andrew A., Sousa, Eduardo, Pimentel, Jorge, Wang, Lisa, Roberts, Jason A. and Lipman, Jeffrey (2011). A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance. Critical Care, 15 (3) R139, 1-8. doi: 10.1186/cc10262

Sutherland, Allison, Thomas, Mervyn, Brandon, Roslyn A., Brandon, Richard B., Lipman, Jeffrey, Tang, Benjamin, McLean, Anthony, Pascoe, Ranald, Price, Gareth, Nguyen, Thu, Stone, Glenn and Venter, Deon (2011). Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis. Critical Care, 15 (3) R149, 1-11. doi: 10.1186/cc10274

Udy, Andrew, Boots, Robert J., Putt, Michael and Lipman, Jeffrey (2011). ARC - Augmented renal clearance. Current Pharmaceutical Biotechnology, 12 (12), 2020-2029. doi: 10.2174/138920111798808446

Higgins, A. M., Pettila, V., Harris, A. H., Bailey, M., Lipman, J., Seppelt, I. M. and Webb, S. A. (2011). The critical care costs of the Influenza A/H1N1 2009 epidemic in Australia and New Zealand. Anaesthesia and Intensive Care, 39 (3), 384-391. doi: 10.1177/0310057x1103900308

Myburgh, John, Bellomo, Rinaldo, Cass, Alan, Finfer, Simon, French, Julie, Gattas, David, Glass, Parisa, Lee, Joanne, Lipman, Jeffrey, Liu, Bette, McArthur, Colin, McGuinness, Shay, Rajbhandari, Dorrilyn, Taylor, Colman and Webb, Steve (2011). The Crystalloid versus Hydroxyethyl Starch Trial: Protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality. Intensive Care Medicine, 37 (5), 816-823. doi: 10.1007/s00134-010-2117-9

Ulldemolins, Marta, Roberts, Jason A., Lipman, Jeffrey and Rello, Jordi (2011). Antibiotic dosing in multiple organ dysfunction syndrome. Chest, 139 (5), 1210-1220. doi: 10.1378/chest.10-2371

Dulhunty, J. M., Paterson, D., Webb, S. A. R. and Lipman, J. (2011). Antimicrobial utilisation in 37 Australian and New Zealand intensive care units. Anaesthesia and Intensive Care, 39 (2), 231-237. doi: 10.1177/0310057x1103900212

Roberts, Jason A., Mehta, Ravindra L. and Lipman, Jeffrey (2011). Sustained low efficiency dialysis allows rational renal replacement therapy, but does it allow rational drug dosing?. Critical Care Medicine, 39 (3), 602-603. doi: 10.1097/CCM.0b013e31820e6a0d

Williams, Julian, Greenslade, Jaimi, Chu, Kevin, Brown, Anthony F., Paterson, David and Lipman, Jeffrey (2011). Prior statin use is not associated with improved outcome in emergency patients admitted with infection: A prospective observational study. Academic Emergency Medicine, 18 (2), 127-134. doi: 10.1111/j.1553-2712.2010.00976.x

Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011). Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 (1) 3, 3.1-3.7. doi: 10.1186/1471-2253-11-3

Ulldemolins, Marta, Roberts, Jason A., Rello, Jordi, Paterson, David L. and Lipman, Jeffrey (2011). The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clinical Pharmacokinetics, 50 (2), 99-110. doi: 10.2165/11539220-000000000-00000

Roberts, Jason, Kirkpatrick, Carl M.J. and Lipman, Jeffrey (2011). Monte Carlo simulations: Maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients. Journal of Antimicrobial Chemotherapy, 66 (2) dkq449, 227-231. doi: 10.1093/jac/dkq449

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin H., Brown, Anthony F. T., Paterson, David and Lipman, Jeffrey (2011). A prospective registry of emergency department patients admitted with infection. BMC Infectious Diseases, 11 (1) 27, 27-1-27-7. doi: 10.1186/1471-2334-11-27

Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 (1) 5, 5.1-5.5. doi: 10.1186/1471-2253-11-5

McGloughlin, Steven, Roberts, Jason A., O'Donoghue, Steven, Martin, Jennifer, Briscoe, Scott and Lipman, Jeffrey (2011). Ganciclovir pharmacokinetics and suggested dosing in continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 37 (1), 90-92. doi: 10.1016/j.ijantimicag.2010.10.003

Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy, Banks, Merrilyn, Dulhunty, Joel, Roberts, Jason A. and Lipman, Jeffrey (2011). Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial. BMJ Open, 1 (2) e000334, 1-8. doi: 10.1136/bmjopen-2011-000334

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2011). Antimicrobial Pharmacokinetic and Pharmacodynamic Issues in the Critically Ill with Severe Sepsis and Septic Shock. Critical Care Clinics, 27 (1), 19-34. doi: 10.1016/j.ccc.2010.09.006

Udy, A, Boots, R, Senthuran, S, Stuart, J, Deans, R, Lassig-Smith, M and Lipman, J (2010). Augmented creatinine clearance in traumatic brain injury. Anesthesia And Analgesia, 111 (6), 1505-1510. doi: 10.1213/ANE.0b013e3181f7107d

Dhanani, Jayesh, Roberts, Jason A., Chew, Michelle, Lipman, Jeffrey, Boots, Robert J., Paterson, David L. and Fraser, John F. (2010). Antimicrobial chemotherapy and lung microdialysis: a review. International Journal of Antimicrobial Agents, 36 (6), 491-500. doi: 10.1016/j.ijantimicag.2010.08.013

Roberts, Jason, Boots, Robert J. and Lipman, Jeffrey (2010). Optimal antibiotic therapy in the management of the lung of the critically ill. Current Reviews in Respiratory Medicine, 6 (4), 253-263. doi: 10.2174/157339810793563749

Douglas, A. E., Holley, A., Udy, A., Lipman, J., Gomersall, C. D., Joynt, G, Freebairn, R. C. and Boots, R. J. (2010). Can learning to sustain life be BASIC? Teaching for the initial management of the critically ill in Australia and New Zealand. Anaesthesia and Intensive Care, 38 (6), 1043-1051. doi: 10.1177/0310057x1003800614

Boots, Robert J., Dulhunty, Joel M., Paratz, Jennifer and Lipman, Jeffrey (2010). Respiratory burns: A clinical review. Current Respiratory Medicine Reviews, 6 (4), 285-291. doi: 10.2174/157339810793563730

Choi, G, Gomersall, CD, Tian, Q, Joynt, GM, Li, AMMY and Lipman, J (2010). Principles of antibacterial dosing in continuous renal replacement therapy. Blood Purification, 30 (3), 195-212. doi: 10.1159/000321488

Boots, Robert J., Udy, Andrew, Holley, Anthony and Lipman, Jeffrey (2010). Preventive strategies for ventilator associated pneumonia. Current Respiratory Medicine Reviews, 6 (4), 238-252. doi: 10.2174/157339810793563758

Playford, EG, Lipman, J and Sorrell, TC (2010). Prophylaxis, empirical and preemptive treatment of invasive candidiasis. Current Opinion in Critical Care, 16 (5), 470-474. doi: 10.1097/MCC.0b013e32833e10e8

Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 (4), 332-339. doi: 10.1016/j.ijantimicag.2010.06.008

Clifford, Michaela E., Banks, Merrilyn D., Ross, Lynda J., Obersky, Natalie A., Forbes, Sharon A., Hegde, Rajeev and Lipman, Jeffrey (2010). A detailed feeding algorithm improves delivery of nutrition support in an intensive care unit. Critical Care and Resuscitation, 12 (3), 149-155. doi: 10.1016/s1441-2772(23)01497-7

Dulhunty, Joel, Webb, Steven, Paterson, David, Bellomo, Rinaldo, Myburgh, John, Roberts, Jason and Lipman, Jeffrey (2010). A survey of antibiotic prescribing practices in Australian and New Zealand intensive care units. Critical Care and Resuscitation, 12 (3), 162-170.

Roberts, Jason A., Field, Jonathan, Visser, Adam, Whitbread, Rosemary, Tallot, Mandy, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2010). Using population pharmacokinetics to determine Gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Antimicrobial Agents and Chemotherapy, 54 (9), 3635-3640. doi: 10.1128/AAC.00222-10

Hayashi, Yoshiro, Roberts, Jason A., Paterson, David L. and Lipman, Jeffrey (2010). Pharmacokinetic evaluation of piperacillin-tazobactam. Expert Opinion on Drug Metabolism and Toxicology, 6 (8), 1017-1031. doi: 10.1517/17425255.2010.506187

Ulldemolins, Marta, Roberts, Jason A., Wallis, Steven C., Rello, Jordi and Lipman, Jeffrey (2010). Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: Special emphasis on unbound pharmacokinetics. Journal of Antimicrobial Chemotherapy, 65 (8) dkq184, 1771-1778. doi: 10.1093/jac/dkq184

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2010). Pharmacokinetics and pharmacodynamics in critically ill patients. Current Opinion in Anesthesiology, 23 (4), 472-478. doi: 10.1097/ACO.0b013e328339ef0a

Bilgrami, I., Roberts, J. A., Wallis, S. C., Thomas, J., Davis, J., Fowler, S., Goldrick, P. B. and Lipman, J. (2010). Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration. Antimicrobial Agents and Chemotherapy, 54 (7), 2974-2978. doi: 10.1128/AAC.01582-09

Ulldemolins, Marta, Roberts, Jason A. and Lipman, Jeffrey (2010). Optimizing antibiotic use in the intensive care unit. Clinical Pulmonary Medicine, 17 (4), 162-169. doi: 10.1097/CPM.0b013e3181e47953

McWhinney, Brett C., Wallis, Steven C., Hillister, Tara, Roberts, Jason A., Lipman, Jeffrey and Ungerer, Jacobus P.J. (2010). Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 (22), 2039-2043. doi: 10.1016/j.jchromb.2010.05.027

Patil, Vikram, Dulhunty, Joel M., Udy, Andrew, Thomas, Peter, Kucharski, Geraldine and Lipman, Jeffrey (2010). Do burn patients cost more?: The intensive care unit costs of burn patients compared with controls matched for length of stay and acuity. Journal of Burn Care and Research, 31 (4), 598-602. doi: 10.1097/BCR.0b013e3181e4d6a4

Corona, A, Bertolini, G, Lipman, J, Wilson, AP and Singer, M (2010). Antibiotic use and impact on outcome from bacteraemic critical illness: The BActeraemia study in intensive care (BASIC). Journal of Antimicrobial Chemotherapy, 65 (6) dkq088, 1276-1285. doi: 10.1093/jac/dkq088

Udy, Andrew A., Putt, Michael T., Shanmugathasan, Sulochana, Roberts, Jason A. and Lipman, Jeffrey (2010). Augmented renal clearance in the Intensive Care Unit: An illustrative case series. International Journal of Antimicrobial Agents, 35 (6), 606-608. doi: 10.1016/j.ijantimicag.2010.02.013

Roberts, Jason A., Ulldemolins, Marta and Lipman, Jeffrey (2010). Meropenem: Focus on its use in serious bacterial infections. Clinical Medicine Reviews in Therapeutics, 2, 1-14. doi: 10.4137/CMRT.S4598

Playford, E. Geoffrey, Lipman, Jeff and Sorrell, Tania C. (2010). Management of invasive candidiasis in the intensive care unit. Drugs, 70 (7), 823-839. doi: 10.2165/10898550-000000000-00000

Roberts, Jason A., Hope, William W. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?. International Journal of Antimicrobial Agents, 35 (5), 419-420. doi: 10.1016/j.ijantimicag.2010.01.022

Gowardman, J. R., Lipman, J. and Rickard, C. M. (2010). Assessment of peripheral arterial catheters as a source of sepsis in the critically ill: A narrative review. Journal of Hospital Infection, 75 (1), 12-18. doi: 10.1016/j.jhin.2010.01.005

Doidge, Michelle, Allworth, Anthony M., Woods, Marion, Marshall, Penelope, Terry, Marshall, O'Brien, Kathryn, Goh, Hwee Mian, George, Narelle, Nimmo, Graeme R., Schembri, Mark A., Lipman, Jeffery and Paterson, David L. (2010). Control of an outbreak of carbapenem-resistant Acinetobacter baumannii in Australia after introduction of environmental cleaning with a commercial oxidizing disinfectant. Infection Control and Hospital Epidemiology, 31 (4), 418-420. doi: 10.1086/651312

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008

Udy, Andrew A., Roberts, Jason A., Boots, Robert J., Paterson, David L. and Lipman, Jeffrey (2010). Augmented renal clearance: Implications for antibacterial dosing in the critically Ill. Clinical Pharmacokinetics, 49 (1), 1-16. doi: 10.2165/11318140-000000000-00000

McNeill, G, Holley, A and Lipman, J (2009). Emphysematous pyelonephritis: an unusual complication of blunt abdominal trauma. Critical Care and Resuscitation, 11 (4), 269-271.

Lipman, Jeffrey and Boots, Rob (2009). A new paradigm for treating infections: "go hard and go home". Critical Care and Resuscitation, 11 (4), 276-281.

Vincent, Jean-Louis, Rello, Jordi, Marshall, John, Silva, Eliezer, Anzueto, Antonio, Martin, Claude D., Moreno, Rui, Lipman, Jeffrey, Gomersall, Charles, Sakr, Yasser and Reinhart, Konrad (2009). International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. Journal of the American Medical Association, 302 (21), 2323-2329. doi: 10.1001/jama.2009.1754

Playford, E. G., Lipman, J., Kabir, M., McBryde, E. S., Nimmo, Graeme R., Lau, A. and Sorrell, T. C. (2009). Assessment of clinical risk predictive rules for invasive candidiasis in a prospective multicentre cohort of ICU patients. Intensive Care Medicine, 35 (12), 2141-2145. doi: 10.1007/s00134-009-1619-9

Ranganathan, Dwarakanathan, Varghese, Julie M., Fassett, Robert G., Lipman, Jeffrey, D'Intini, Vincent, Healy, Helen and Roberts, Jason A. (2009). Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study. BMC Nephrology, 10 (1) 42, 1-6. doi: 10.1186/1471-2369-10-42

Chatterjee, I., Dulhunty, J.M., Iredell, J., Gallagher, J.E., Sud, A., Woods, M. and Lipman, J. (2009). Predictors and outcome associated with an Enterococcus positive isolate during intensive care unit admission. Anaesthesia and Intensive Care, 37 (6), 976-982. doi: 10.1177/0310057x0903700610

Li, A. M. M. Y., Gomersall, C. D., Choi, G., Tian, Q., Joynt, G. M. and Lipman, J. (2009). A systematic review of antibiotic dosing regimens for septic patients receiving continuous renal replacement therapy: do current studies supply sufficient data?. Journal of Antimicrobial Chemotherapy, 64 (5) dkp302, 929-937. doi: 10.1093/jac/dkp302

Thirlwell, J., Holley, A., Udy, A., Lipman, J. and Paratz, J. (2009). The microcirculation, regional blood flow and tissue oxygenation: Will new technologies drive new resuscitation goals?. Anaesthesia and Intensive Care, 37 (6), 891-891.

Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08

Roberts, Jason A., Udy, Andrew A., O'Donoghue, Stephen, Briscoe, Scott, Paterson, David L. and Lipman, Jeffrey (2009). Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis. International Journal of Antimicrobial Agents, 34 (4), 383-384. doi: 10.1016/j.ijantimicag.2009.05.005

Holley, A, Udy, A and Lipman, J (2009). The microcirculation, regional blood flow and tissue oxygenation: will new technologies drive new resuscitation goals?. Anaesthesia and Intensive Care, 37 (5), 700-702. doi: 10.1177/0310057X0903700524

Roberts, JA and Lipman, J (2009). Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing. Journal of Pharmacy Practice and Research, 39 (3), 219-222. doi: 10.1002/j.2055-2335.2009.tb00457.x

Roberts, Jason A., Coulthard, Mark G., Addison, Russell S., Foot, Carole and Lipman, Jeffrey (2009). Midazolam metabolism: Implications for individualised dosing?. Journal of Pharmacy Practice and Research, 39 (3), 198-201. doi: 10.1002/j.2055-2335.2009.tb00452.x

Roberts, Jason A. and Lipman, Jeffrey (2009). Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy. Critical Care Medicine, 37 (8), 2491-2492. doi: 10.1097/CCM.0b013e3181aee840

Choi, Gordon, Gomersall, Charles D., Tian, Qi, Joynt, Gavin M., Freebairn, Ross and Lipman, Jeffrey (2009). Principles of antibacterial dosing in continuous renal replacement therapy. Critical Care Medicine, 37 (7), 2268-2282. doi: 10.1097/CCM.0b013e3181aab3d0

Roberts, Jason A., Webb, Steven, Paterson, David, Ho, Kwok M. and Lipman, Jeffrey (2009). A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics. Critical Care Medicine, 37 (6), 2071-2078. doi: 10.1097/CCM.0b013e3181a0054d

Holley, Anthony, Dulhunty, Joel, Blot, Stijn, Lipman, Jeffrey, Lobo, Suzana, Dancer, Craig, Rello, Jordi and Dimopoulos, George (2009). Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units. International Journal of Antimicrobial Agents, 33 (6), 554.e1-554.e7. doi: 10.1016/j.ijantimicag.2008.10.035

Boots, RJ, Dulhunty, JM, Paratz, JD and Lipman, J (2009). Respiratory Complications in Burns: An Evolving Spectrum of Injury. Clinical Pulmonary Medicine, 16 (3), 132-138. doi: 10.1097/CPM.0b013e3181a39032

Baek-Nam, Kim, Peleg, Anton Y., Lodise, Thomas P., Lipman, Jeffrey, Li, Jian, Nation, Roger and Paterson, David L. (2009). Management of meningitis due to antibiotic-resistant Acinetobacter species. Lancet Infectious Diseases, 9 (4), 245-255. doi: 10.1016/S1473-3099(09)70055-6

Udy, A., O'Donoghue, S., D'Intini, V., Healy, H. and Lipman, J. (2009). Point of care measurement of plasma creatinine in critically ill patients with acute kidney injury. Anaesthesia, 64 (4), 403-407. doi: 10.1111/j.1365-2044.2008.05818.x

Udy, A., Senthuran, S. and Lipman, J. (2009). Airway obstruction due to a pre-vertebral haematoma following difficult central line insertion - implications for ultrasound guidance and review of the literature. Anaesthesia and Intensive Care, 37 (2), 309-313. doi: 10.1177/0310057x0903700219

Ho, KM and Lipman, J (2009). An update on C-reactive protein for intensivists.. Anaesthesia and Intensive Care, 37 (2), 234-241. doi: 10.1177/0310057x0903700217

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44

Roberts, Jason A. and Lipman, Jeffrey (2009). Pharmacokinetic issues for antibiotics in the critically ill patient. Critical Care Medicine, 37 (3), 840-851. doi: 10.1097/CCM.0b013e3181961bff

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08

Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6) R189, xx-xx. doi: 10.1186/cc8184

Udy, A., Roberts, J. A., Boots, R. J. and Lipman, J. (2009). You only find what you look for: The importance of high creatinine clearance in the critically ill. Anaesthesia and Intensive Care, 37 (1), 11-13. doi: 10.1177/0310057x0903700123

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

Joel M. Dulhunty, Robert J. Boots, Michael J. Rudd, Michael J. Muller and Jeffrey Lipman (2008). Increased fluid resuscitation can lead to adverse outcomes in major-burn injured patients, but low mortality is achievable. Burns, 34 (8), 1090-1097. doi: 10.1016/j.burns.2008.01.011

John A Myburgh, Alisa Higgins, Alina Jovanovska, Lipman, Jeffrey, Naresh Ramakrishnan and John Santamaria (2008). A comparison of epinephrine and norepinephrine in critically ill patients. Intensive Care Medicine, 34 (12), 2226-2234. doi: 10.1007/s00134-008-1219-0

Dulhunty, Joel M., Lipman, Jeffrey and Finfer, Simon (2008). Does severe non-infectious SIRS differ from severe sepsis? Results from a multi-centre Australian and New Zealand intensive care unit study. Intensive Care Medicine, 34 (9), 1654-1661. doi: 10.1007/s00134-008-1160-2

Roberts, Jason A, Lipman, Jeffrey, Blot, Stijn and Rello, Jordi (2008). Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?. Current Opinion in Critical Care, 14 (4), 390-396. doi: 10.1097/MCC.0b013e3283021b3a

Roberts, Jason A., Kruger, Peter, Paterson, David L. and Lipman, Jeffrey (2008). Antibiotic resistance - what's dosing got to do with it?. Critical Care Medicine, 36 (8), 2433-2440. doi: 10.1097/CCM.0b013e318180fe62

D. M. Roberts, J. A. Roberts, R. J. Boots, R. Mason and J. Lipman (2008). Lessons learnt in the pharmacokinetic analysis of the effect of haemoperfusion for acute overdose with sustained-release diltiazem. Anaesthesia, 63 (7), 714-718. doi: 10.1111/j.1365-2044.2008.05477.x

Jason A. Roberts, Jennifer D. Paratz and Jeffrey Lipman (2008). Continuous infusion of [beta]-lactams in the intensive care unit—Best way to hit the target?. Critical Care Medicine, 36 (5), 1663-1664. doi: 10.1097/CCM.0b013e3181704625

Roberts, Jason A., Paratz, Jennifer D., Paratz, Elizabeth D., Boots, Rob J. and Jeffrey Lipman (2008). Continuous infusion of time-dependent antibiotics: lung pharmacokinetics and pharmacodynamics. Clinical Pulmonary Medicine, 15 (3), 167-172. doi: 10.1097/CPM.0b013e3181729d3d

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013

Thomas, Peter J., Paratz, Jennifer D., Lipman, Jeffrey and Stanton, Warren R. (2007). Lateral positioning of ventilated intensive care patients: A study of oxygenation, respiratory mechanics, hemodynamics, and adverse events. Heart & Lung, 36 (4), 277-286. doi: 10.1016/j.hrtlng.2006.10.008

Dalley, Andrew J., Lipman, Jeffrey, Venkatesh, Bala, Rudds, Michael, Roberts, Michael S. and Cross, Sheree E. (2007). Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. Journal of Antimicrobial Chemotherapy, 60 (1), 166-169. doi: 10.1093/jac/dkm128

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007). Bedside prediction of central venous catheter insertion depth. British Journal of Anaesthesia, 98 (5), 695-695. doi: 10.1093/bja/aem080

Paterson, D. L. and Lipman, J. (2007). Editorial: Infections in the intensive care unit - important questions remain. Critical Care and Resuscitation, 9 (1), 3-4.

Marik, Paul E. and Lipman, Jeffrey (2007). The definition of septic shock: Implications for treatment. Critical Care and Resuscitation, 9 (1), 101-103.

Chatterjee, I., Iredell, J. R., Woods, M. and Lipman, J. (2007). The implications of enterococci for the intensive care unit. Critical Care and Resuscitation, 9 (1), 69-75.

Roberts, Jason A., Webb, Steven A. R. and Lipman, Jeffrey (2007). Cefepime versus ceftazidime: Considerations for empirical use in critically ill patients. International Journal of Antimicrobial Agents, 29 (2), 117-128. doi: 10.1016/j.ijantimicag.2006.08.031

Roberts, J. A., Boots, R., Rickard, C. M., Thomas, P., Quinn, J., Roberts, D. M., Richards, B. and Lipman, J. (2007). Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study. Journal of Antimicrobial Chemotherapy, 59 (2), 285-291. doi: 10.1093/jac/dkl478

Roberts, Jason A. and Lipman, Jeffrey (2007). Optimizing use of ß-lactum antibiotics in the critically ill. Seminars in Respiratory and Critical Care Medicine, 28 (6), 579-585. doi: 10.1055/s-2007-996404

Holley, A., Cartner, M. and Lipman, J. (2007). Acute respiratory distress in a bleomycin primed patient: a new use for nitric oxide. Anaesthesia and Intensive Care, 35 (1), 86-90. doi: 10.1177/0310057x0703500112

Freshwater-Turner, D., Udy, A., Lipman, J., Deans, R., Stuart, J., Boots, R., Hegde, R. and McWhinney, B.C. (2007). Autonomic dysfunction in tetanus - what lessons can be learnt with specific reference to alpha-2 agonists?. Anaesthesia, 62 (10), 1066-1070. doi: 10.1111/j.1365-2044.2007.05217.x

Roberts, Jason A., Paratz, Jennifer, Paratz, Elizabeth, Krueger, Wolfgang A. and Lipman, Jeffrey (2007). Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role. International Journal of Antimicrobial Agents, 30 (1), 11-18. doi: 10.1016/j.ijantimicag.2007.02.002

Paterson, David and Lipman, Jeffery (2007). Returning to the pre-antibiotic era in the critically ill: The XDR problem. Critical Care Medicine, 35 (7), 1789-1791. doi: 10.1097/01.CCM.0000269352.39174.A4

Roos, J. F., Lipman, J. and Kirkpatrick, C. M. J. (2007). Population pharmacokinetics and pharmacodynamics of cefpirome in critically ill patients against Gram-negative bacteria. Intensive Care Medicine, 33 (5), 781-788. doi: 10.1007/s00134-007-0573-7

Shorr, A. F. and Lipman, J. (2007). Resistance in the intensive care unit: Whose problem is it and how can intensivists help?. Critical Care Medicine, 35 (1), 299-301. doi: 10.1097/01.CCM.0000251292.74846.00

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007). The Entrapped Central Venous Catheter. British Journal of Anaesthesia, 98 (1), 89-92. doi: 10.1093/bja/ael286

Eisen, Damon P., Dean, Melinda M., Thomas, Peter, Marshall, Penny, Gerns, Natalie, Heatley, Sue, Quinn, Josephine, Minchinton, Robyn M. and Lipman, Jeff (2006). Low mannose-binding lectin function is associated with sepsis in adult patients. FEMS Immunology and Medical Microbiology, 48 (2), 274-282. doi: 10.1111/j.1574-695X.2006.00144.x

Thomas, Peter J., Paratz, Jennifer D., Stanton, Warren R., Deans, Renae and Lipman, Jeffrey (2006). Positioning practices for ventilated intensive care patients: Current practice, indications and contraindications. Australian Critical Care, 19 (4), 122-132. doi: 10.1016/S1036-7314(06)80025-1

Shorr, Andrew F., Jackson, William L. and Lipman, Jeffrey (2006). Making the wrong choice: Consequences for patients with infections due to methicillin-resistant Staphylococcus aureus. Critical Care Medicine, 34 (8), 2239-2241. doi: 10.1097/01.CCM.0000229635.52805.50

Paratz, Jennifer and Lipman, Jeffrey (2006). Manual hyperinflation causes norepinephrine release. Heart & Lung, 35 (4), 262-268. doi: 10.1016/j.hrtlng.2005.12.002

Roberts, J. A. and Lipman, J. (2006). Antibacterial dosing in intensive care: Pharmacokinetics, degree of disease and pharmacodynamics of sepsis. Clinical Pharmacokinetics, 45 (8), 755-773. doi: 10.2165/00003088-200645080-00001

Roos, Juliana F., Bulitta, Jurgen, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2006). Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units. Journal of Antimicrobial Chemotherapy, 58 (5), 987-993. doi: 10.1093/jac/dkl349

Finfer, S., Felton, T., Blundell, A. and Lipman, J. (2006). Estimate of the number of patients eligible for treatment with drotrecogin alfa (activated) based on differing international indications: Post-hoc analysis of an inception cohort study in Australia and New Zealand. Anaesthesia And Intensive Care, 34 (2), 184-190. doi: 10.1177/0310057x0603400217

Tian, Qi, Gomersall, Charles D., Wong, April, Leung, Patricia, Choi, Gordon, Joynt, Gavin M., Tan, Perpetua and Lipman, Jeff (2006). Effect of drug concentration on adsorption of levofloxacin by polyacrylonitrile haemofilters. International Journal of Antimicrobial Agents, 28 (2), 147-150. doi: 10.1016/j.ijantimicag.2006.03.025

Li, J., Rayner, C. R., Nation, R. L., Deans, R., Boots, R., Widdecombe, N., Douglas, A. and Lipman, J. (2005). Pharmacokinetics of colistin methanesulfonate and colistin in a critically ill patient receiving continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 49 (11), 4814-4815. doi: 10.1128/AAC.49.11.4814-4815.2005

Ho, K. M., Lipman, J., Dobb, G. J. and Webb, S. A. R. (2005). The use of prophylactic fluconazole in immunocompetent high-risk surgical patients: A meta-analysis. Critical Care, 9 (6) R710, R710-R717. doi: 10.1186/cc3883

Lipman, Jeffrey (2005). Is the end-game penetration (of the airway)?. Critical Care Medicine, 33 (7), 1654-1655. doi: 10.1097/01.CCM.0000170183.83774.F6

Thomas, Peter J., Williams, Marie and Lipman, Jeffrey (2005). Influence of academic qualifications, place of employment and prior research experience on physiotherapy research practice. The Internet Journal of Allied Health Sciences and Practices, 3 (3).

Iredell, J. and Lipman, J. (2005). Antibiotic resistance in the intensive care unit: A primer in bacteriology. Anaesthesia and Intensive Care, 33 (2), 188-195. doi: 10.1177/0310057x0503300206

Rechner, I. J. and Lipman, J. (2005). The costs of caring for patients in a tertiary referral Australian intensive care unit. Anaesthesia and Intensive Care, 33 (4), 477-482. doi: 10.1177/0310057x0503300409

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. E. (2005). Australian and New Zealand practice in intensive care (ANZPIC II: The spectrum of practice in the diagnosis and management of pneumonia in patients requiring mechanical ventilation. Anaesthesia and Intensive Care, 33 (1), 87-100. doi: 10.1177/0310057X0503300115

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. E. (2005). Disease risk and mortality prediction in intensive care patients with pneumonia. Australian and New Zealand practice in intensive care (ANZPIC II). Anaesthesia And Intensive Care, 33 (1), 101-111. doi: 10.1177/0310057X0503300116

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. F. (2005). Australian and New Zealand practice in intensive care (ANZPIC II): Predictors of physician confidence to diagnose pneumonia and determine illness severity in ventilated patients. Anaesthesia and Intensive Care, 33 (1), 112-119. doi: 10.1177/0310057X0503300117

Gous, Andries, Lipman, Jeffrey, Scribante, Juan, Tshukutsoane, Shephelia, Hon, Hubert, Pinder, Mary, Mathivha, Rudo, Verhoef, Lia and Stass, Heino (2005). Fluid shifts have no influence on ciprofloxacin pharmacokinetics in intensive care patients with intra-abdominal sepsis. International Journal of Antimicrobial Agents, 26 (1), 50-55. doi: 10.1016/j.ijantimicag.2005.04.005

Choi, Gordon, Gomersall, Charles D., Lipman, Jeff, Wong, April, Joynt, Gavin M., Leung, Patricia, Ramsay, Sarah J. and Ho, Oi Man (2004). The effect of adsorption, filter material and point of dilution on antibiotic elimination by haemofiltration - An in vitro study of levofloxacin. International Journal of Antimicrobial Agents, 24 (5), 468-472. doi: 10.1016/j.ijantimicag.2004.06.005

DelDot, Megan E., Lipman, Jeffrey and Tett, Susan E. (2004). Vancomycin pharmacokinetics in critically ill patients receiving continuous venovenous haemodiafiltration. British Journal of Clinical Pharmacology, 58 (3), 259-268. doi: 10.1111/j.1365-2125.2004.02143.x

Rickard, Claire M., Lipman, Jeff, Courtney, Mary, Siversen, Rosemary and Daley, Peter (2004). Routine changing of intravenous administration sets does not reduce colonization or infection in central venous catheters. Infection Control And Hospital Epidemiology, 25 (8), 650-655. doi: 10.1086/502456

O'Connor, E., Venkatesh, B., Mashongonyika, C., Lipman, J., Hall, J. and Thomas, P. (2004). Serum procalcitonin and C-reactive protein as markers of sepsis and outcome in patients with neurotrauma and subarachnoid haemorrhage. Anaesthesia And Intensive Care, 32 (4), 465-470. doi: 10.1177/0310057x0403200402

Koroloff, Natasha, Boots, Robert, Lipman, Jeff, Thomas, Peter, Rickard, Claire and Coyer, Fiona (2004). A randomised controlled study of the efficacy of hypromellose and Lacri-Lube combination versus polyethylene/Cling wrap to prevent corneal epithelial breakdown in the semiconscious intensive care patient. Intensive Care Medicine, 30 (6), 1122-1126. doi: 10.1007/s00134-004-2203-y

Finfer, Simon, Bellomo, Rinaldo, Lipman, Jeffrey, French, Craig, Dobb, Geoffrey and Myburgh, John (2004). Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Medicine, 30 (4), 589-596. doi: 10.1007/s00134-004-2157-0

Lipman, Jeffrey, Wallis, Steven C. and Boots, Robert J. (2003). Cefepime versus cefpirome: The importance of creatinine clearance. Anesthesia And Analgesia, 97 (4), 1149-1154. doi: 10.1213/01.ANE.0000077077.54084.B0

French, Craig J., Bellomo, Rinaldo, Finfer, Simon R., Lipman, Jeffery, Chapman, Marianne, Boyce, Neil W. and ANZICS Clinical Trials Group (2002). Appropriateness of red blood cell transfusion in Australasian intensive care practice. Medical Journal Australia, 177 (10), 548-551.

Pinder, M., Bellomo, R. and Lipman, Jeffrey (2002). Pharmacological principles of antibiotic prescription in the critically ill. Anaesth Intensive Care, 30 (2), 134-144.

Venkatesh, Bala, Shen, Qiaomei and Lipman, Jeffrey (2002). Continuous measurement of cerebral blood flow velocity using transcranial Doppler reveals significant moment-to-moment variability of data in healthy volunteers and in patients with subarachnoid hemorrhage. Critical Care Medicine, 30 (3), 563-569. doi: 10.1097/00003246-200203000-00011

Paratz, Jennifer, Lipman, Jeffrey and McAuliffe, Mary (2002). Effect of manual hyperinflation on hemodynamics, gas exchange, and respiratory mechanics in ventilated patients. Journal of Intensive Care Medicine, 17 (6), 317-324. doi: 10.1177/0885066602238034

Boots, R. and Lipman, J. (2002). High dependency units: Issues to consider in their planning. Anaesthesia And Intensive Care, 30 (3), 348-354.

Lipman, J., Gous, A., Mathivha, L., Tshukutsoane, S., Scribante, J., Hon, H., Pinder, M., Riera-Fanego, J., Verhoef, L. and Stass, H. (2002). Ciprofloxacin pharmacokinetic profiles in paediatric sepsis: how much ciprofloxacin is enough?. Intensive Care Medicine, 28 (4), 493-500. doi: 10.1007/s00134-002-1212-y

Rickard, Claire M., Wallis, Steven C., Courtney, Mary, Lipman, Jeff and Daley, Peter J. P. (2002). Intravascular administration sets are accurate and in appropriate condition after 7 days of continuous use: an in vitro study. Journal of Advanced Nursing, 37 (4), 330-337. doi: 10.1046/j.1365-2648.2002.02099.x

Joynt, G. M., Lipman, J., Gomersall, C. D., Young, R. J., Wong, E. L. Y. and Gin, T. (2001). The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients. Journal of Antimicrobial Chemotherapy, 47 (4), 421-429. doi: 10.1093/jac/47.4.421

Wallis, Steven C., Mullany, Dan V., Lipman, Jeffrey, Rickard, Claire M. and Daley, Peter J. (2001). Pharmacokinetics of ciprofloxacin in ICU patients on continuous veno-venous haemodiafiltration. Intensive Care Medicine, 27 (4), 665-672. doi: 10.1007/s001340100857

Lipman, Jeffrey, Wallis, Steven C., Rickard, Claire M. and Fraenkel, David (2001). Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing. Intensive Care Medicine, 27 (2), 363-370. doi: 10.1007/s001340000741

Lipman, J, Allworth, A and Wallis, SC (2000). Cerebrospinal fluid penetration of high doses of intravenous ciprofloxacin in meningitis. Clinical Infectious Diseases, 31 (5), 1131-1133. doi: 10.1086/317462

Fraenkel, D. J., Rickard, C. and Lipman, J. (2000). Can we achieve consensus on central venous catheter-related infections?. Anaesthesia and Intensive Care, 28 (5), 475-490. doi: 10.1177/0310057X0002800501

Boots, RJ, Lipman, J, O'Callaghan, J, Scott, P and Fraser, J (2000). The treatment of tetanus with intrathecal baclofen. Anaesthesia and Intensive Care, 28 (4), 438-442.

Venkatesh, B, Morgan, TJ and Lipman, J (2000). Subcutaneous oxygen tensions provide similar information to ileal luminal CO2 tensions in an animal model of haemorrhage shock. Intensive Care Medicine, 26 (5), 592-600. doi: 10.1007/s001340051209

Meacher, R., Venkatesh, B. and Lipman, J. (1999). Acute respiratory distress syndrome precipitated by transjugular intrahepatic porto-systemic shunting for severe hepatic veno-occlusive disease. Is it due to pulmonary leucostasis? [2]. Intensive Care Medicine, 25 (11), 1332-1333. doi: 10.1007/s001340051070

Lipman, J, Wallis, SC and Rickard, C (1999). Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modelling indicates improved troughs with revised dosing. Antimicrobial Agents and Chemotherapy, 43 (10), 2559-2561.

Lipman, J., Wallis, S. C. and Rickard, C. (1999). Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modeling indicates improved troughs with revised dosing. Antimicrobial Agents and Chemotherapy, 43 (10), 2559-2561. doi: 10.1128/AAC.43.10.2559

Boots, RJ, Lipman, J and Weitzman, L (1999). Keeping relatives informed by the internet. Lancet, 354 (9177), 517-518. doi: 10.1016/S0140-6736(05)75556-2

Jones, A. R.R., Venkatesh, B. and Lipman, J. (1999). Vancomycin resistance in gram-positive cocci - Old bugs, new tricks, confusing terminology. Anaesthesia and Intensive Care, 27 (4), 396-399. doi: 10.1177/0310057X9902700412

Shen, Quaomei, Stuart, Janine, Venkatesh, Balasubramanian, Wallace, Jenny and Lipman, Jeffrey (1999). Inter observer variability of the transcranial doppler ultrasound technique: Impact of lack of practice on the accuracy of measurement. Journal of Clinical Monitoring and Computing, 15 (3-4), 179-184. doi: 10.1023/A:1009925811965

Piccolo, R., Lipman, J., Hon, H. and Burrows, R. (1999). Analgesia and sedation in the critically ill - a practical approach. South Africal Journal of Surgery, 37 (1), 15-20.

Lipman, J, Gomersall, CD, Gin, T, Joynt, GM and Young, RJ (1999). Continuous infusion ceftazidime in intensive care: a randomized controlled trial. Journal of Antimicrobial Chemotherapy, 43 (2), 309-311. doi: 10.1093/jac/43.2.309

Liebenberg, C. S., Raw, R., Lipman, J., Moyes, D. G. and Cleaton-Jones, P. E. (1999). Small tidal volume ventilation using a zero deadspace tracheal tube. British Journl of Anaesthesia, 82 (2), 213-216. doi: 10.1093/bja/82.2.213

Jones, A. R., Venkatesh, B. and Lipman, J. (1999). Vancomycin resistance in gram-positive cocci-- old bugs, new tricks, confusing terminology. Anaesthesia & Intensive Care, 27 (4), 396-399.

Lipman, J. and Piccolo, R. (1998). The inflammatory conundrum - where exactly do we stand?. South African Medical Journal, 88 (11), 1441-1442. doi: 10.1186/s13071-016-1799-4

Scribante, J, Lipman, J and Saadia, R (1998). Good clinical research practice: What is it and is it possible in the intensive care unit?. Anaesthesia and Intensive Care, 26 (5), 568-574. doi: 10.1177/0310057x9802600515

Lipman, J, Scribante, J, Gous, AGS, Hon, H and Tshukutsoane, S (1998). Pharmacokinetic profiles of high-dose intravenous ciprofloxacin in severe sepsis. Antimicrobial Agents and Chemotherapy, 42 (9), 2235-2239. doi: 10.1128/aac.42.9.2235

Pinder, M. and Lipman, J. (1998). Interpretation of lactate levels in critical illness. South African Journal of Surgery, 36 (3), 93-96.

Pinder, M., Tshukutsoane, S., Scribante, J., Piccolo, R. and Lipman, J. (1998). Critical care research and pre-emptive informed consent: A practical approach used in Chris Hani Baragwanath ICU. Intensive Care Medicine, 24 (4), 353-357. doi: 10.1007/s001340050579

Wolff, M., Shafran, S. D., Potgieter, P. D., Laloo, V. G., Irusen, E. M., Cassim, I. M., Garber, G. E., Louie, T. J., San Juan, J. A., Nogueras, C., Street, M., Bleichner, G., Sollet, J. P., Gibert, C., Calvat, S., Giunta, F., Corsini, V., Lipman, J., Hedström, S. Å, Juhlin-Dannfelt, M., Borulf, B., Edbrooke, D., Holmdahl, T., Grossman, R. F., Laaban, J. P., Rabbat, A., Lindblom, A., Ahlgren, I., Clara, L. ... Wilson, W. R. (1998). Comparison of strategies using cefpirome and ceftazidime for empiric treatment of pneumonia in intensive care patients. Antimicrobial Agents and Chemotherapy, 42 (1), 28-36.

Burrows, R. C., Lipman, J., Piccolo, R. and Hon, H. (1997). Sedation and analgesia in the ICU - What evidence-based medicine is there?. South African Medical Journal, 87 (8)

Lipman, J. and Saadia, R. (1997). Fungal infections in critically ill patients. Rates are rising but diagnosis and treatment remain difficult. British Medical Journal, 315 (7103), 266-267.

Young, Robert J., Lipman, Jeffrey, Gin, Tony, Gomersall, Charles D., Joynt, Gavin M. and Oh, Teik E. (1997). Intermittent bolus dosing of ceftazidime in critically ill patients. Journal of Antimicrobial Chemotherapy, 40 (2), 269-273. doi: 10.1093/jac/40.2.269

Morgan, T. J., Venkatesh, B. and Lipman, J. (1997). Gastric tonometry: quo vadis?. South African Journal of Surgery, 35 (2), 51-52.

Lipman, J. and Pinder, M. (1997). What is feasible and what is affordable in intensive care?. South African Medical Journal, 87 (2), 127-128.

Wells, M. and Lipman, J. (1997). Measurements of glomerular filtration in the intensive care unit are only a rough guide to renal function. South African Journal of Surgery, 35 (1), 20-23.

Wells, M. and Lipman, J. (1997). Pitfalls in the prediction of renal function in the intensive care unit. South African Journal of Surgery, 35 (1), 16-19.

Lipman, J. and Lichtman, A. R. (1997). Critical care in Africa: North to South and the future with special reference to Southern Africa. Critical Care Clinics, 13 (2), 255-265. doi: 10.1016/S0749-0704(05)70308-0

Joynt, G. M., Lipman, J., Gomersall, C. D., Tan, I. and Scribante, J. (1997). Gastric intramucosal pH and blood lactate in severe sepsis. Anaesthesia, 52 (8), 726-732. doi: 10.1111/j.1365-2044.1997.173-az0307.x

Martinot, A., Grandbastien, B., Leclerc, F., Riera-Fanego, J. F. and Lipman, J. (1997). Performance of the pediatric risk of mortality score [2]. Critical Care Medicine, 25 (4), 716-717. doi: 10.1097/00003246-199704000-00028

Leong, W. C., Lipman, J., Hon, H. and Brouckaert, N. T. (1997). Severe soft-tissue infections - A diagnostic challenge: The need for early recognition and aggressive therapy. South African Medical Journal, 87 (5 SUPPL. 1), 648-654.

Lipman, Jeffrey and Cumpston, Philip H. V. (1997). Does intensive care always have to be expensive care?. Clinical Pulmonary Medicine, 4 (6), 334-338. doi: 10.1097/00045413-199711000-00005

Saadia, R. and Lipman, J. (1996). Duration of antibiotic treatment in surgical infections of the abdomen. Antibiotics and the gut. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement (576), 39-41.

Lipman, J., Crewe-Brown, H. H., Saunders, G. L. and Gous, A. G.S. (1996). Subtleties of antibiotic dosages -- do doses and intervals make a difference in the critically ill?. South African Journal of Surgery, 34 (4), 160-162.

Saadia, R. and Lipman, J. (1996). Multiple organ failure after trauma. British Medical Journal, 313 (7057), 573-574.

Scribante, J., Muller, M. E. and Lipman, J. (1996). Development and validation of a critical care patient classification system. American Journal of Critical Care, 5 (4), 282-288.

Scribante, J., Muller, M. E. and Lipman, J. (1996). A guideline for competency of the critical care nurse. American Journal of Critical Care, 5 (3), 217-226.

Bothma, P. A., Joynt, G. M., Lipman, J., Hon, H., Mathala, B., Scribante, J. and Kromberg, J. (1996). Accuracy of pulse oximetry in pigmented patients. South African Medical Journal, 86 (5 SUPPL.), 594-596.

Joynt, G., Doedens, L., Lipman, J. and Bothma, P. (1996). High-dose adrenaline with low systemic vascular resistance and symmetrical peripheral gangrene. South African Journal of Surgery, 34 (2), 99-101.

Blumberg, L., Lee, R. R., Lipman, J. and Beards, S. (1996). Predictors of mortality in severe malaria: A two-year experience in a non-endemic area. Anaesthesia and Intensive Care, 24 (2), 217-223.

Strauss, A., Finder, M., Lipman, J. and Conidaris, M. (1996). Acute stridor as a presentation of bilateral abductor vocal cord paralysis. Anaesthesia, 51 (11), 1046-1048. doi: 10.1111/j.1365-2044.1996.tb15002.x

Wells, Mike, Riera-Fanego, Jacinto F., Luyt, David K., Dance, Melanie and Lipman, Jeffrey (1996). Poor discriminatory performance of the Pediatric Risk of Mortality (PRISM) score in a South African intensive care unit. Critical Care Medicine, 24 (9), 1507-1513. doi: 10.1097/00003246-199609000-00013

Gous, A. G S, Dance, M. D., Lipman, J., Luyt, D. K., Mathivha, R. and Scribante, J. (1995). Changes in vancomycin pharmacokinetics in critically ill infants. Anaesthesia and Intensive Care, 23 (6), 678-682.

Pinder, M., Armon, K., Lipman, J. and Schein, M. (1995). Systemic response to Gram-positive and Gram-negative infections - Comparison and contrast. South African Journal of Surgery, 33 (3), 121-125.

Young, R. J., Lipman, J. and Freebairn, R. C. (1995). Accidental intra-arterial adrenaline administration. Anaesthesia and Intensive Care, 23 (4), 488-489.

Litmanovitch, M., Joynt, G. M., Skoularigis, J. and Lipman, J. (1995). Emergency percutaneous balloon mitral valvotomy in a patient with septic shock. Chest, 108 (2), 570-572. doi: 10.1378/chest.108.2.570

Pinder, M., Hon, H., Irmay, F. and Lipman, J. (1995). Failed nasogastric intubation in undiagnosed carcinoma of the oesophagus. Anaesthesia and Intensive Care, 23 (3), 370-372.

Saunders, G. L., Lipman, J. and Klugman, K. (1994). Invasive candidiasis in the ICU - Pathogenesis and management strategy. South African Journal of Surgery, 32 (4), 154-156.

Freebairn, R., Joynt, G. M., Lipman, J. and Bothma, P. A. (1994). A double-blind comparison of vecuronium administered by the Springfusor® infusion device to vecuronium by intermittent bolus injection in critically ill adult patients. Anaesthesia and Intensive Care, 22 (5), 580-585.

Lipman, J. and Bothma, P. A. (1994). Sepsis and inflammation - A move towards clarity but still a bleak future. South African Medical Journal, 84 (2), 58-59.

BEARDS, S. C., DOEDENS, L., JACKSON, A. and LIPMAN, J. (1994). A comparison of arterial lines and insertion techniques in critically ill patients. Anaesthesia, 49 (11), 968-973. doi: 10.1111/j.1365-2044.1994.tb04316.x

Freebairn, R. C. and Lipman, J. (1994). Continuous venovenous haemodiafiltration - An audit demonstrating control of electrolytes with haemodynamic stability in the critically ill. South African Journal of Surgery, 32 (2), 77-82.

BEARDS, S. C. and LIPMAN, J. (1994). Decreased cardiac index as an indicator of tension pneumothorax in the ventilated patient. Anaesthesia, 49 (2), 137-141. doi: 10.1111/j.1365-2044.1994.tb03371.x

Beards, S. C., Lipman, J., Bothma, P. A. and Joynt, G. M. (1994). Esmolol in a case of severe tetanus. Adequate haemodynamic control achieved despite markedly elevated catecholamine levels. South African Journal of Surgery, 32 (1), 33-35.

Beards, S. C., Joynt, G. M. and Lipman, J. (1994). Haemodynamic and oxygen transport response during exchange transfusion for severe falciparum malaria. Postgraduate Medical Journal, 70 (829), 801-804. doi: 10.1136/pgmj.70.829.801

Joynt, G. M. and Lipman, J. (1994). Humidification in intensive care. South African Journal of Surgery, 32 (1), 23-30.

Shelly, M. P., Mosoane, R., Mathivha, L. R. and Lipman, J. (1994). Informed consent in the Baragwanath Intensive Care Unit. Clinical Intensive Care, 5 (2), 80-82.

Beards, S. C., Robertson, L. J., Jackson, A. and Lipman, J. (1994). Malignant astrocytoma of the cervico-medullary junction masquerading as Guillain - Barré syndrome. Postgraduate Medical Journal, 70 (825), 499-502. doi: 10.1136/pgmj.70.825.499

BEARDS, S. C., KRAUS, P. and LIPMAN, J. (1994). Paralytic ileus as a complication of atropine therapy following severe organophosphate poisoning. Anaesthesia, 49 (9), 791-793. doi: 10.1111/j.1365-2044.1994.tb04454.x

Bothma, P. A., Lipman, J., Moyes, D. G. and Joynt, G. M. (1994). Tension pneumoperitoneum aggravating respiratory failure. A case report. South African Journal of Surgery, 32 (1), 31-32.

Joynt, G. M. and Lipman, J. (1994). The use of heat and moisture exchangers in critically ill patients. Care of the Critically Ill, 10 (6), 271-275.

Freebairn, R. C. and Lipman, J. (1993). Renal replacement therapy for the critically ill - Precarious progress. Part II. Technical aspects and clinical application. South African Journal of Surgery, 31 (4), 147-151.

Kraus, P. A., Lipman, J., Lee, C. C.J., Wilson, W. E., Scribante, J., Barr, J., Mathivha, L. R. and Brown, J. M. (1993). Acute lung injury at Baragwanath ICU: An eight-month audit and call for consensus for other organ failure in the adult respiratory distress syndrome. Chest, 103 (6), 1832-1836. doi: 10.1378/chest.103.6.1832

Marik, P. E., Scribante, J. and Lipman, J. (1993). Candidiasis in an intensive care unit. South African Journal of Surgery, 31 (1), 24-27.

Lipman, J., Wilson, W., Kobilski, S., Scribante, J., Lee, C., Kraus, P., Cooper, J., Barr, J. and Moyes, D. (1993). High-dose adrenaline in adult in-hospital asystolic cardiopulmonary resuscitation: A double-blind randomised trial. Anaesthesia and Intensive Care, 21 (2), 192-196.

Marik, P., Kraus, P., Sribante, J., Havlik, I., Lipman, J. and Johnson, D. W. (1993). Hydrocortisone and tumor necrosis factor in severe community-acquired pneumonia: A randomized controlled study. Chest, 104 (2), 389-392. doi: 10.1378/chest.104.2.389

Marik, P. E., Kraus, P. and Lipman, J. (1993). Intensive care utilisation: The Baragwanath experience. Anaesthesia and Intensive Care, 21 (4), 396-399.

Marshall, P. and Lipman, J. (1993). Mechanical ventilatory support. A brief overview with a simple practical approach. South African Journal of Surgery, 31 (1), 19-23.

Freebairn, R. C. and Lipman, J. (1993). Renal replacement therapy for the critically ill - Precarious progress: Part I. Definitions and physiological aspects. South African Journal of Surgery, 31 (3), 114-120.

BEARDS, S. C., FREEBAIRN, R. C. and Lipman, J. (1993). Successful use of continuous veno‐venous haemofiltration to treat profound fluid retention in severe peripartum cardiomyopathy. Anaesthesia, 48 (12), 1065-1067. doi: 10.1111/j.1365-2044.1993.tb07528.x

Kraus, P. and Lipman, J. (1992). Erythropoietin in a patient following multiple trauma. Anaesthesia, 47 (11), 962-964. doi: 10.1111/j.1365-2044.1992.tb03199.x

Wilson, W., Lipman, J., Scribante, J., Kobilski, S., Lee, C., Krause, P., Cooper, J. and Barr, J. (1992). Septic shock: Does adrenaline have a role as a first-line inotropic agent?. Anaesthesia and Intensive Care, 20 (4), 470-474.

Marik, Paul Ellis, Lipman, Jeffrey, Kobilski, Sacha and Scribante, Juan (1991). A prospective randomized study comparing once- versos twice-daily amikadn dosing in critically ill adult and paediatric patients. Journal of Antimicrobial Chemotherapy, 28 (5), 753-764. doi: 10.1093/jac/28.5.753

Marik, P. E., Kussman, B. D., Lipman, J. and Kraus, P. (1991). Acetazolamide in the treatment of metabolic alkalosis in critically ill patients. Heart and Lung: Journal of Critical Care, 20 (5 I), 455-458.

Arregui, L. M., Moyes, D. G., Lipman, J. and Fatti, L. P. (1991). Comparison of disease severity scoring systems in septic shock. Critical Care Medicine, 19 (9), 1165-1171. doi: 10.1097/00003246-199109000-00012

Marik, P. E. and Lipman, J. (1991). Failure of early electrocardiogram to predict successful thrombolysis. Effect of stunned myocardium?. Heart and Lung: Journal of Critical Care, 20 (3), 224-227.

Lipman, J., Cornwell, J., Kraus, P. and Raw, K. (1991). Typhoid fever: A undescribed cause of adult respiratory distress syndrome. Anaesthesia and Intensive Care, 19 (1), 124-126.

Lipman, J., Roux, A. and Kraus, P. (1991). Vasoconstrictor effects of adrenaline in human septic shock. Anaesthesia and Intensive Care, 19 (1), 61-65.

Marik, P. E., Lipman, J., Eidelman, I. J. and Erskine, P. J. (1990). Clinical predictors of early death in acute myocardial infarction. A prospective study of 233 patients. South African Medical Journal, 77 (4), 179-182.

Kraus, P. A. and Lipman, J. (1990). Coronary embolism causing myocardial infarction. Intensive Care Medicine, 16 (3), 215-216. doi: 10.1007/BF01724807

Kraus, P. A., Lipman, J. and Becker, P. J. (1990). Acute preload effects of furosemide. Chest, 98 (1), 124-128. doi: 10.1378/chest.98.1.124

Routier, R. J., Lipman, J. and Brown, K. (1989). Difficulty in weaning from respiratory support in a patient with the intermediate syndrome of organophosphate poisoning. Critical Care Medicine, 17 (10), 1075-1076. doi: 10.1097/00003246-198910000-00023

Plit, M. L., Lipman, J., Eidelman, J. and Gavaudan, J. (1988). Catheter related infection. A plea for consensus with review and guidelines. Intensive Care Medicine, 14 (5), 503-509. doi: 10.1007/BF00263521

Lawrenson, J. B., Klugman, K. P., Eidelman, J. I., Wasas, A., Miller, S. D. and Lipman, J. (1988). Fatal infection caused by a multiply resistant type 3 pneumococcus. Journal of Clinical Microbiology, 26 (8), 1590-1591. doi: 10.1128/JCM.26.8.1590-1591.1988

Plit, M. L., Rumbak, M. J., Lipman, J. and Eidelman, J. (1987). Invasive vascular catheterisation in the critically ill. South African Medical Journal, 72 (4), 245-248.

Lipman, J., James, M. F.M., Erskine, J., Plit, M. L., Eidelman, J. and Esser, J. D. (1987). Autonomic dysfunction in severe tetanus: Magnesium sulfate as an adjunct to deep sedation. Critical Care Medicine, 15 (10), 987-988. doi: 10.1097/00003246-198710000-00022

Parks, P., Lipman, J. and Eidelman, J. (1987). Carbamate toxicity. A case report. South African Medical Journal, 72 (3), 222-222.

Marik, P. E., Angel, M. E., Eidelman, J. and Lipman, J. (1987). Subarachnoid haemorrhage. A report of 2 cases. South African Medical Journal, 71 (6), 389-390.

Lipman, J., Roos, C. P., Eidelman, J. and Plit, M. (1986). A comparison between right atrial and pulmonary arterial oxygen tensions. South African Medical Journal, 70 (6), 351-353.

Lipman, J. (1985). Pitfalls in the interpretation of pulmonary capillary wedge pressure. South African Medical Journal, 67 (5), 174-177.

Plit, M., Lipman, J., Roos, C. P., Clausen, L., Decker, G. A., Josselsohn, E., Katz, T. and Bester, R. (1984). The principles, structure and function of the J.G. Strijdom Hospital pre-operative assessment clinic. South African Journal of Surgery, 22 (3), 203-209.

Lipman, J. and Plit, M. (1984). A guide to the rational use of dopamine, dobutamine and isoprenaline in patients who need inotropic support. South African Medical Journal, 65 (13), 506-509.

Lipman, J., Hesdorffer, C. and Fernandes Costa, F. (1984). Vitamin B12 levels in the prolonged use of sodium nitroprusside. Critical Care Medicine, 12 (3), 161-163. doi: 10.1097/00003246-198403000-00002

Roos, C. P., Plit, M., Lipman, J., Eidelman, J. and Marshall, P. R. (1982). Persistent left superior vena cava complicating haemodynamic monitoring. A case report. South African Medical Journal, 62 (18), 661-663.

Lipman, J., Roos, C. P., Plit, M., Bukofser, S., Rumbak, M., Kobrin, S. M., Griffiths, R. F. and Marshall, P. R. (1982). The correlation between cardiac output and mixed venous oxygen tension. South African Medical Journal, 62 (17), 611-613.

Lipman, J., Jardine, I., Roos, C. and Dreosti, L. (1982). Intravenous calcium chloride as an antidote to verapamil-induced hypotension. Intensive Care Medicine, 8 (1), 55-57. doi: 10.1007/BF01686855

Lipman, J. and Wing, J. (1981). The adult respiratory distress syndrome. A review, some thoughts and a few new ideas. South African Medical Journal, 59 (22), 779-782.

Ho, Kwok M., Honeybul, Stephen, Rao, Sudhakar, Zellweger, Rene, Misur, Philip, Corcoran, Tomas B., Wibrow, Bradley, Geelhoed, Elizabeth, Baker, Ross, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Rogers, Frederick B. and Edibam, Cyrus (2018). BENEFITS AND HARMS OF EARLY PROPHYLACTIC INFERIOR VENA CAVA FILTER IN MAJOR TRAUMA PATIENTS: A MULTICENTER RANDOMIZED-CONTROLLED-TRIAL (RCT). 41st Annual Conference on Shock, Scottsdale Az, Jun 09-12, 2018. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Christensen, R., Eley, V. A., Smith, M., Jackson, D., Ryan, R., van Zundert, A., Wallis, S., Lipman, J. and Roberts, J. (2018). Does Cefazolin Prophylaxis During Elective Bariatric Caesarean Section Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?. The National Scientific Congress of the Australian Society of Anaesthetists, Perth Convention and Exhibition Centre, Perth, Western Australia, 7-10th October 2017. New South Wales, Australia: Australian Society of Anaesthetists.

Ryan, R., Jackson, D. , Eley, V. A., Christensen, R., van Zundert, A ., Wallis, S., Lipman, J. and Roberts, J. (2018). Does Cefazolin Prophylaxis During Elective Bariatric Surgery Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?. The National Scientific Congress of the Australian Society of Anaesthetists, Perth Convention and Exhibition Centre, Perth, Western Australia, 7-10th October. New South Wales, Australia: The Australian Society of Anaesthetists.

Eley, Victoria , Callaway, Leonie , van Zundert, Andre , Lipman, Jeffrey and Gallois, Cindy (2016). “Early epidural analgesia”: Practice guidelines are interpreted variably by specialist anaesthetists caring for obese parturients. Australian and New Zealand College of Anaesthetists Annual Scientific Meeting, Auckland, New Zealand, April 30- May 4th 2016.

Adnan, Syamhanin, Li, Janice X., Lipman, Jeffrey, Wallis, Steve C. and Roberts, Jason A. (2012). Pharmacokinetics of meropenem in critically ill patients with indwelling surgical drains. 13th Annual Scientific Meeting Antimicrobials 2012, Brisbane Convention and Exhibition Centre, Brisbane, 23 - 25 February 2012. Brisbane QLD, Australia: Australian Society of Antimicrobial.

Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew, Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2010). Vancomycin Dosing in Critically Ill Patients Using Population Pharmacokinetics to Develop Personalised Dosing Regimens to Achieve Target Concentrations by Continuous Infusion. 40th Critical Care Congress, San Diego Ca, Jan 15-19, 2011. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x

Putt, M. T., Roberts, J. A., Udy, A. A., Martin, J. H., Jarrett, P., Salmon, N. and Lipman, J. (2010). Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics. 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-2001-7

Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x

DE Waele, J, Moreno, R, Anzueto, A and Lipman, J (2010). INFECTIONS AND USE OF ANTIBIOTICS IN PATIENTS ADMITTED FOR SEVERE ACUTE PANCREATITIS: DATA FROM THE EPIC2 STUDY. 23rd Annual Meeting of the European-Society-of-Intensive-Care-Medicine, Barcelona SPAIN, OCT 09-13, 2010. NEW YORK: SPRINGER.

Roberts, J. A., Field, J., Visser, A., Whitbread, R., Lipman, J. and Kirkpatrick, C. (2009). Using Population Pharmacokinetics To Determine Gentamicin Dosing during Extended Daily Diafiltration in Critically Ill Patients with Acute Kidney Injury. 22nd Annual Congress of the European Society of Intensive Care Medicine, Vienna, Austria, 11-14 October 2009. NEW YORK: SPRINGER.

Cross, Sheree, Dalley, Andrew, Kanchanamala, Ranasinghe, Lipman, Jeffery, Roberts, Michael, Robertson, Thomas and Venkatesh, Bala (2008). The effect of thermal injury on interstitial tissue antibiotic distribution and the choice of resuscitation fluid. Australian Health and Medical Research Congress (AHMRC) 2008, Brisbane, Australia, 16-21 November 2008.

Cross, Sheree, Dalley, Andrew, Lipman, Jeffery, Ranasinghe, Kanchanamala, Roberts, Michael, Robertson, Thomas and Venkatesh, Bala (2008). The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats. 14th Congress of the International Society for Burn Injuries, Montreal, Canada, 7-11 September 2008.

Saadia, R. and Lipman, J. (1996). Antibiotics and the gut.

Churchyard, G. J., Wilson, W. E., Lipman, J. and Kalk, W. J. (1992). The relationship between circulating thyroxin level and changes in clinical status of critically ill, septic and non-septic patients.

Marik, P. E., Havlik, I., Monteagudo, F. S.E. and Lipman, J. (1991). The pharmacokinetics of amikacin in critically ill adult and paediatric patients: Comparison of once- versus twice-daily dosing regimens.

Professor Jeffrey Lipman

Researcher biography

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Conference Papers