The Screening Antifungal Exposure in Intensive Care Units (SAFE-ICU) study, published in Intensive Care Medicine, provides important evidence on the adequacy of antifungal drug exposure in critically ill patients, an area where dosing guidance remains limited.
Resistance Optimised Antibiotic Dosing (The ROAD Study): Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? A pilot study.
Antimicrobial stability is an important consideration for treatment planning and service delivery in outpatient parenteral antimicrobial therapy (OPAT) programmes. Regulation of stability assessment varies by region, and conflicting guidance and standards exist. This leads to disparity of equity in access and limits availability of certain antimicrobials for managing infections in the outpatient setting.